Results 1 to 10 of about 56,023 (262)

The characteristics and the multiple functions of integrin β1 in human cancers. [PDF]

J Transl Med, 2023
Integrins, which consist of two non-covalently linked α and β subunits, play a crucial role in cell–cell adhesion and cell-extracellular matrix (ECM) interactions.
Sun L, Guo S, Xie Y, Yao Y.
europepmc   +2 more sources

Prognostic value of β1 integrin expression in colorectal liver metastases

, 2015
Integrins are cell surface adhesion molecules (CAM) that regulate via intercellular and cell-matrix signaling various cellular processes including wound healing, cell differentiation, division, growth, migration and metastatic dissemination.
Vassos, Nikolaos, Merkel, Susanne, Feiersinger, Fabian, Geppert, Carol, Croner, Roland S., Rau, Tilman, Stürzl, Michael, Hohenberger, Werner   +7 more
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Die Rolle von Notch und Integrin-β1 in der Muskelentwicklung

, 2014
Craniofacial muscles are small skeletal muscles involved in mastication, swallowing, vocalization and facial expression. In contrast to trunk and limb muscles, the majority of craniofacial muscles originate from head mesoderm.
Czajkowski, Maciej
core   +1 more source

Decreased integrin β1 impairs the motility of CRC cells.

, 2014
A, Western blot analyses assessed the protein level of integrin β1 in SW480 cells transfected with a siRNA against integrin β1 (β1 siRNA) or negative control siRNA (Scramble) at 20 nM and 50 nM respectively.
Yao Li (154923), Ruomei Qi (323213), Tomoya Isaji (519295), Yanyang Zhao (459902), Jian Li (41607), Jianguo Gu (198655), Gang Miao (519294)   +6 more
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Endothelial Cells Regulate Cardiac Myocyte Reorganisation Through β1-Integrin Signalling

, 2015
Background: In normal hearts, capillaries are densely distributed throughout the myocardial tissue, and the cross-talk between myocytes and capillary endothelial cells plays a pivotal role in regulating cardiac development, maturation and function ...
Zhengxing Lian, Renyue Wei, Yu Zhang, Hai Li, Zhonghua Liu, Yanhua Zhao, Jing Ma   +6 more
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USP40 protects podocytes by deubiquitylating integrin β1. [PDF]

Biochem Biophys Res Commun
Mikami N, Fukushima T, Takematsu H, Kiuchi Z, Fukuhara D, Tanaka E, Kimura T, Suehiro J, Fukutomi T, Kobayashi K, Pastan I, Nagata M, Takano T, Matsusaka T, Akimoto Y, Kawanishi K, Yan K.   +16 more
europepmc   +1 more source

Integrin β1 Demarks Precursors of Brain-Residing Antibody-Secreting Cells in Multiple Sclerosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Kuiper KL, Bogers L, Rip J, van Hasselt Y, Melief MJ, Wierenga-Wolf AF, Klein Kranenbarg RAM, Bindels E, van de Werken HJG, de Beukelaar J, Smets I, Wokke B, Smolders J, van Luijn MM.   +13 more
europepmc   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17-Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC. [PDF]

Adv Sci (Weinh)
Cui L, Si S, Ye M, Lin P, Zou M, Lin Y, Chen X, Guo B, Sun W, Zhao X.   +9 more
europepmc   +1 more source

PACSIN2 regulates platelet integrin β1 hemostatic function. [PDF]

J Thromb Haemost, 2023
Biswas R, Boyd EK, Eaton N, Steenackers A, Schulte ML, Reusswig F, Yu H, Drew C, Kahr WHA, Shi Q, Plomann M, Hoffmeister KM, Falet H.   +12 more
europepmc   +1 more source

Structural and Functional Aspects of β1 Integrin Signalling

, 2006
Integrins are transmembrane glycoproteins primarily mediating interactions of cells with the extracellular matrix. Each receptor is a complex of one α- and one β-subunit with affinity for a diverse set of ligands.
Nilsson, Stina
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