ß1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli [PDF]
, 2005 Integrins are cell adhesion receptors which mediate interactions between the extracellular matrix and the actin cytoskeleton. They are heterodimers composed of α and β subunits. As adhesion receptors, integrins are important for cell-cell and cell-matrix
Li, Na
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Decreased integrin β1 in lipid raft inhibits proliferation and migration of HPS rat serum-induced PMVECs [PDF]
Jichu yixue yu linchuang, 2021 Objective To investigate the effects of integrin β1 within lipid raft on PMVECs. Methods PMVECs were divided into four groups: control group; HPS group: HPS; group and MβCD group: the cells were pretreated with 0.01 mol/L MβCD for 1 hour, and
GAO Jing, ZHOU Jia-qi
doaj
Human Parechovirus 1 Infection Occurs via αVβ1 Integrin. [PDF]
PLoS ONE, 2016 Human parechovirus 1 (HPeV-1) (family Picornaviridae) is a global cause of pediatric respiratory and CNS infections for which there is no treatment.
Pirjo Merilahti +2 more
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NADPH oxidase (NOX) in the heart : the interplay of NOX-derived ROS in β1-integrin-induced survival signalling [PDF]
, 2011 Moderate levels of reactive oxygen species (ROS) act as mediators in cellular signalling processes. An important source of cardiac ROS is the highly expressed NADPH oxidase (NOX) family isoform NOX2. However, little is known about whether NOX-derived ROS
Rosc-Schlüter, Berit Ines
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Integrin-mediated cell-matrix interaction in physiological and pathological blood vessel formation [PDF]
, 2011 Physiological as well as pathological blood vessel formation are fundamentally dependent on cell-matrix interaction. Integrins, a family of major cell adhesion receptors, play a pivotal role in development, maintenance, and remodeling of the vasculature.
Stephan Niland +3 more
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Integrin β1 regulates the invasion and radioresistance of laryngeal cancer cells by targeting CD147
Cancer Cell International, 2018 Background Increased expression of integrin β1 has been reported to correlate with progression and therapy resistance in many types of cancers. The aim of this study was to investigate the effects of integrin β1 on the invasion and radioresistance of ...
Li Li, Xiaoxia Dong, Feng Peng, Li Shen
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European Journal of Cell Biology, 2023 The expression of the angiotensin-converting enzyme 2 (ACE2) is altered in multiple chronic kidney diseases like hypertension and renal fibrosis, where the signaling from the basal membrane proteins is critical for the development and progression of the ...
Md Saimon Mia +8 more
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Galectin-3 induces clustering of CD147 and integrin-β1 transmembrane glycoprotein receptors on the RPE cell surface. [PDF]
PLoS ONE, 2013 Proliferative vitreoretinopathy (PVR) is a blinding disease frequently occurring after retinal detachment surgery. Adhesion, migration and matrix remodeling of dedifferentiated retinal pigment epithelial (RPE) cells characterize the onset of the disease.
Claudia S Priglinger +11 more
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The role of NCAM signaling and its effector protein, [beta]1-integrin, in tumor progression [PDF]
, 2007 Neural Cell Adhesion Molecule (NCAM) is a member of the large family of Ca2+independent, immunoglobulin (Ig)-like cell adhesion molecules. So far, its function in homophilic and heterophilic interactions has been mainly studied in neuronal cells, where ...
Kren, Angelika
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Regulation of opticin on bioactivity of retinal vascular endothelial cells cultured in collagen [PDF]
International Journal of Ophthalmology, 2020 AIM: To investigate the effects of collagen and opticin on the bioactivity of human retinal vascular endothelial cells (hRVECs), and explore its regulations by integrins and RhoA/ROCK1 signal pathway.
Yue Xing, Xue-Ke Li, Si-Duo Lu, Jin Ma
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