Results 141 to 150 of about 197,418 (252)

PECULIARITIES OF THERAPY WITH LONG ACTING β2-ADRENERGIC AGONISTFORMOTEROL FOR ASTHMA IN CHILDREN

Педиатрическая фармакология, 2006
Information on clinical use of long acting β2-adrenergic agonist formoterol in children with asthma is presented. Pharmacokinetics and pharmacodymanics are scrutinized in detail.
Yu.G. Levina, L.S. Namazova, V.V. Botvin'eva, N.I. Voznesenskaya, R.M. Torshkhoeva, K.E. Efendieva   +5 more
doaj  

Revisiting Platelet‐Activating Factor in Asthma: An Exploratory Metabolomics Analysis of PAF C‐18:1 and Type 2 Inflammation

Allergy, EarlyView.
Noeul Kang, Young Jin Pyung, Deog Kyeom Kim, Cheol‐Heui Yun, Hyun Woo Lee   +4 more
wiley   +1 more source

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

British Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan, Rwdah Mohamed Alameri, Yasir S. Raouf, Damien Maurel, Naiem Ahmad Wani, Anatoliy Shmygol, Irfa Anwar, Heng B. See, Elizabeth K. M. Johnstone, Elodie Dupuis, Eric Trinquet, Kevin D. G. Pfleger, Emilia Oueis, Mohammed Akli Ayoub   +13 more
wiley   +1 more source

A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes. [PDF]

Biofactors, 2022
Melis M, Tang XH, Attarwala N, Chen Q, Prishker C, Qin L, Gross SS, Gudas LJ, Trasino SE.   +8 more
europepmc   +1 more source

Kininase I drives angiotensin II‐induced hypertension through activation of the bradykinin B1 receptor

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kininase I, comprising carboxypeptidase N (CPN) and carboxypeptidase M, regulates kinin activity and is up‐regulated during injury, inflammation and immune activation. Under these conditions, kininase I converts bradykinin and kallidin into des‐Arg kinins, primary endogenous agonists of the bradykinin B1 receptor (R ...
Acacia White, Drew Theobald, Alexandra Johnston, David A. Tulis, Johanna Hannan, Srinivas Sriramula   +5 more
wiley   +1 more source

A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease. [PDF]

J Biol Chem, 2021
Tang XH, Melis M, Lu C, Rappa A, Zhang T, Jessurun J, Gross SS, Gudas LJ.   +7 more
europepmc   +1 more source

Psychological Stress Promotes Tumor Growth in Hepatocellular Carcinoma Models Through Myeloid Signaling

Cancer Science, EarlyView.
Psychological stress promotes hepatocellular carcinoma progression through coordinated regulation of macrophages and neutrophils. Noradrenaline activates ADRB2 signaling in intratumoral macrophages, leading to CXCL2 production and neutrophil recruitment.
Keita Ogawa, Takahiro Aoki, Tatsuya Kaneko, Hongxuan Wang, Daiki Shimizu, Daisuke Katsumi, Iori Kojima, Hidekazu Tanaka, Kiwamu Motoyoshi, Ko Ozaki, Katsuhiro Nishimura, Tomohisa Iinuma, Mariko Takami, Shinichiro Motohashi   +13 more
wiley   +1 more source

Successful treatment with inhaled corticosteroid/long-acting β₂-agonist in a case of allergic bronchopulmonary mycosis caused by Schizophyllumcommune. [PDF]

Respir Med Case Rep, 2023
Sekiya M, Sakamoto S, Sekiguchi R, Sadamoto S, Sasaki M, Kamei K, Shibuya K, Kishi K.   +7 more
europepmc   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

Cancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren, Jing Jia, Tingting Li, Yiwei Li, Nanxiang Shen, Yun Shi, Zhe Wang, Hao Fan, Guangli Sun, Guanying Xiong, Gang Li, Rui Peng   +11 more
wiley   +1 more source

Prolonged β2-agonist treatment enhances muscle-specific glucose uptake in individuals with overweight and obesity: a randomized placebo-controlled trial. [PDF]

Nat Commun
Van Lier PMG, van de Weijer T, Vanweert F, Brouwers K, Nijssen KMR, Schaart G, Moonen-Kornips E, van Beek SMM, Springer S, Wierts R, Joris PJ, Schrauwen-Hinderling VB, Phielix E, Bengtsson T, Schrauwen P, Hoeks J.   +15 more
europepmc   +1 more source