Results 81 to 90 of about 6,127 (166)

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source

Inflammatory Bowel Disease in Children and Young People Living With Overweight or Obesity: A Critical Narrative Review

Obesity Reviews, EarlyView.
ABSTRACT Inflammatory bowel disease is a chronic inflammatory disorder affecting the gastrointestinal tract. It mainly comprises of Crohn's disease and ulcerative colitis. Its global prevalence has risen simultaneously with overweight and obesity among children and young people over the last decades.
Razan Algarni, Efstathia Papada, Adrian Brown   +2 more
wiley   +1 more source

A Single-Center, Randomized Double-Blind Placebo-Controlled Study Evaluating the Effects of Poly-Gamma-Glutamate on Human NK Cell Activity after an 8-Week Oral Administration in Healthy Volunteers [PDF]

, 2013
A randomized double-blind placebo-controlled immunity study involving 99 healthy volunteers was performed to investigate the effect of poly-γ-glutamate (γ-PGA) on human natural killer (NK) cell activity in peripheral blood.
Ahrom Kim, Haryoung Poo, Jai-Chul Choi, Jang-Hee Hong, Kyung-Soo Kim, Moon-Hee Sung, Sung-Jin Kim, Tae-Young Lee   +7 more
core   +2 more sources

Hypoxic‐hypocapnic red blood cells in PAGGSM additive solution before and after gamma irradiation show improved metabolism

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Hypoxic/hypocapnic (HH) treatment and storage conditions have been shown to reduce oxidative stress and improve red blood cell (RBC) quality. This study aimed to validate a good manufacturing practice HH RBC product for obtaining the licence for routine use in patients, by comparison with normoxic RBCs both without ...
Soroth Chey, Jacqueline Maier, Samuel Sowemimo‐Coker, Reinhard Henschler   +3 more
wiley   +1 more source

Metabolic engineering of Bacillus amyloliquefaciens LL3 for enhanced poly‐γ‐glutamic acid synthesis

Microbial Biotechnology, 2019
Summary Poly‐γ‐glutamic acid (γ‐PGA) is a biocompatible and biodegradable polypeptide with wide‐ranging applications in foods, cosmetics, medicine, agriculture and wastewater treatment.
Weixia Gao, Yulian He, Fang Zhang, Fengjie Zhao, Chao Huang, Yiting Zhang, Qiang Zhao, Shufang Wang, Chao Yang   +8 more
doaj   +1 more source

Identification of the Role of swrA in Copper Induced Poly-gamma-glutamic Acid Production in Bacillus subtilis [PDF]

, 2022
Each year over 2.8 million Americans are infected by an antibiotic resistant strain of bacteria with over 35, 000 dying as a result (CDC). The lack of development of new antibiotics has renewed interest in the antimicrobial properties of copper.
Addison, Maya
core   +1 more source

Scour‐Conditioned Seismic Fragility Analysis of Monopile‐Supported Offshore Wind Turbines

Earthquake Engineering &Structural Dynamics, Volume 55, Issue 4, Page 947-967, 10 April 2026.
ABSTRACT Monopile‐supported offshore wind turbines (MS‐OWTs) are increasingly deployed in seismic coastal regions, where they face compound risks from earthquake loading and seabed scour. While past studies have addressed these hazards separately, seismic fragility under evolving scour conditions remains insufficiently understood. This study introduces
Francisco Pinto, Rodrigo Astroza, Felipe Vicencio, Raffaele De Risi   +3 more
wiley   +1 more source

Genomic characterization and related functional genes of γ- poly glutamic acid producing Bacillus subtilis

BMC Microbiology
γ- poly glutamic acid (γ-PGA), a high molecular weight polymer, is synthesized by microorganisms and secreted into the extracellular space. Due to its excellent performance, γ-PGA has been widely used in various fields, including food, biomedical and ...
Jiayue Zhu, Xue Wang, Jianan Zhao, Fang Ji, Jun Zeng, Yanwen Wei, LiLi Xu, Guoying Dong, Xingyuan Ma, Chengmin Wang   +9 more
doaj   +1 more source

Nanoparticulate adjuvants and delivery systems for allergen immunotherapy [PDF]

, 2012
In the last decades, significant progress in research and clinics has been made to offer possible innovative therapeutics for the management of allergic diseases. However, current allergen immunotherapy shows limitations concerning the long-term efficacy
Esparza, I. (Irene), Ferrer, M. (Marta), Gamazo, C. (Carlos), Irache, J.M. (Juan Manuel), Sanz, M.L. (María Luisa), Souza, J. (Juliana) de   +5 more
core   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source