Results 101 to 110 of about 26,551 (120)

Untangling Alzheimer's disease with β-secretase inhibitors

Drug Discovery Today, 2000
openaire   +2 more sources

The substrate repertoire of γ-secretase/presenilin

Seminars in Cell and Developmental Biology, 2020
Gokhan Guner, Stefan F Lichtenthaler
exaly  

Alzheimer’s-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions

Cell, 2017
Maria Szaruga, Bogdan Munteanu, Katrien Horre   +2 more
exaly  

Cholesterol-Dependent γ-Secretase Activity in Buoyant Cholesterol-Rich Membrane Microdomains

Neurobiology of Disease, 2002
Andrew C Nyborg, Mikio Shoji, Takeshi Kawarabayashi   +2 more
exaly  

γ‐Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct

EMBO Molecular Medicine, 2017
Yong Ran, Fokhrul Hossain, Antonio Pannuti   +2 more
exaly  

Evidence that γ-secretase mediates oxidative stress-induced β-secretase expression in Alzheimer's disease

Neurobiology of Aging, 2010
Dong-Gyu Jo, Thiruma V Arumugam, Ha-Na Woo   +2 more
exaly  

γ-Secretase: proteasome of the membrane?

Nature Reviews Molecular Cell Biology, 2004
Raphaël Kopan, Ma Xenia G Ilagan, Kopan Raphaël   +2 more
exaly  

GSAP modulates γ-secretase specificity by inducing conformational change in PS1

Proceedings of the National Academy of Sciences of the United States of America, 2019
Eitan Wong, George P Liao, Peng Xu
exaly  

γ-Secretase inhibitors and modulators

Biochimica Et Biophysica Acta - Biomembranes, 2013
Todd E Golde, Edward H Koo, Kevin M Felsenstein   +2 more
exaly  

α- and β-secretase: profound changes in Alzheimer’s disease

Biochemical and Biophysical Research Communications, 2002
David Dawbarn, Shelley J Allen
exaly