Results 81 to 90 of about 741,455 (295)
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
Plato's concept of ἀνάμνησις in the Phaidon
Dieser Aufsatz betrachtet einige zentrale Aspekte der Charakterisierung der ἀνάμνησις im Phaedo 72e‘ 77a. Er analysiert die innerlich hervorrufende Natur der ἀνάμνησις und die diese Hervorrufung beeinträchtigenden Faktoren von λήθη. Der Phaedo zeigt, 1.
openaire +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Εικονογραφημένη - Έτος Δ' τευχ. 37-48 (Νοέμβριος 1907 - Οκτώβριος 1908)
Στο έτος Δ' περιλαμβάνονται 12 ...
core
Effect of tsa2Δ deletion on the lethality of tsa1Δ rad51Δ trr1Δ.
Tetrad analysis of meiotic products of diploid strain tsa1Δ/TSA1 tsa2Δ/TSA2 rad51Δ/RAD51 trr1Δ/TRR1. These four loci are unlinked. 220 tetrads were dissected. 55 segregants of each genotype were expected.Effect of tsa2Δ deletion on the lethality of tsa1Δ
Roland Chanet (374699) +11 more
core +1 more source
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Hemoglobin-δ-gluconolactone assay.
Results are mean ±SD and were compared with untreated blood (A = control blood; B = blood+δ-glu; C = blood+δ-glu+10 mM AG; D = blood+δ-glu+10 µM MF; E = blood+δ-glu+100 µM MF; F = blood+δ-glu+500 µM MF; G = blood+ δ-glu+1 mM MF; H = blood+ δ-glu+1 mM PM;
Uzma Shahab (285629) +7 more
core +1 more source
Pancuronium sensitivity of nAChR chimeras, δ/ε/δ and ε/δ/ε.
(A1), (B1), Pancuronium dependent inhibition of nAChRs. Data for the δ- and the ε-types are identical to those shown in Fig 1C. Data points are shown as mean ± sem. (A2), (B2), IC50s of chimeric subunits.
Souhei Sakata (17138188) +1 more
core +1 more source
Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket +14 more
wiley +1 more source
Observation of the Ïð3686ß decays into Σ+ Σ - Ï and Σ+ Σ - Ï
Based on (2712.4 +/- 14.3) x 106 events recorded at the psi(3686) nominal mass collected with the BESIII detector operating at the BEPCII collider, the psi(3686) -> E +/- E over bar -omega and E +/- E over bar -phi decays are observed for the first time with statistical significances of 13.8 sigma and 7.6 sigma, respectively.
Ablikim, M. +7 more
openaire +1 more source

