Results 71 to 80 of about 19,726 (227)

Unresolved conflict in workers' compensation: The impact of legal representation on workers' compensation benefits

open access: yesJournal of Risk and Insurance, EarlyView.
Abstract We estimate the causal effect of attorney involvement on the indemnity benefits workers receive after their injuries. To address the fundamental challenge that claims and injuries may differ on unmeasured dimensions that affect both attorney involvement and benefits received, we propose and use two instruments.
Bogdan Savych, David Neumark
wiley   +1 more source

Evaluation of buprenorphine as optimisation of postoperative analgesia in feral cats undergoing ovariohysterectomy under field conditions

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives The objective of this prospective, randomised, blinded, observational clinical study was to investigate the effect of subcutaneously administered buprenorphine on postoperative pain in female feral cats undergoing ovariohysterectomy as part of a trap‐neuter‐return programme.
V. Heitzmann   +3 more
wiley   +1 more source

The Influence of Gene Polymorphism OPRM1 118A/G on the Perception of Pain and Pharmacodynamics of Narcotic Analgesics

open access: yesОбщая реаниматология, 2014
The polymorphism of μ-opioid receptor is one of the most studied polymorphisms that affect the activity of narcotic analgesics. Despite that there are a large number of publications dealing with the problem, the obtained results are not being currently ...
V. M. Zhenilo, O. A. Makharin
doaj   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Consensus on the Management of Anesthetic Agents During Digestive Motility Measurements and Proposal of a Standardized Protocol for Anesthesia (French Neuro Gastroenterology Group GFNG and Committee of Anesthetic French Experts)

open access: yesNeurogastroenterology &Motility, EarlyView.
Anesthesia can alter measurements during digestive endoscopies, yet no standardized protocol currently exists. Two expert groups—the French Neuro‐Gastroenterology Group (GFNG) and anesthesiologists—used the Delphi method to reach a consensus on which drugs have an influence (91 amendments), ultimately resulting in a proposed anesthesia protocol (28 ...
Domitille Renard   +29 more
wiley   +1 more source

μ Opioid Modulation of Sensorimotor Functional Connectivity in Autism: Insights From a Pharmacological Neuroimaging Investigation Using Tianeptine

open access: yesBiological Psychiatry Global Open Science
Background: Reproducible patterns of atypical functional connectivity (FC) of sensorimotor and higher-order networks have previously been identified in the autistic brain. However, the neurosignaling pathways underpinning these differences remain unclear.
Mihail Dimitrov   +18 more
doaj   +1 more source

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

open access: yesNeurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao   +6 more
wiley   +1 more source

Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom‐Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres

open access: yesAngewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Strained spirocyclic spiro[2.3]hexane and its heteroatom‐containing derivatives, including previously underrepresented 5‐oxa‐1‐azaspiro[2.3]hexanes and 1,5‐diazaspiro[2.3]hexanes, were synthesized via a modular approach of insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into alkenes, carbonyls and imines.
Philipp Natho   +10 more
wiley   +2 more sources

Cervical epidural catheter for administration of detomidine and morphine in a model of carpal synovitis in the horse

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To determine the analgesic effects of detomidine and morphine administered by cervical epidural catheter (CEC) on a model of thoracic limb pain. Study design Prospective, randomized, blinded crossover study. Animals Five adult horses.
Veronica L. Edwards   +3 more
wiley   +1 more source

Efficacy of D,L-methadone in the treatment of glioblastoma in vitro

open access: yesCNS Oncology, 2018
Aim: Recently, D,L-methadone has been put forward as adjuvant treatment in glioblastoma (GBM). Methods: We analyzed the μ-opioid receptor expression in a set of GBM cell lines and investigated the efficacy of D,L-methadone alone and in combination with ...
Konstantin Brawanski   +9 more
doaj   +1 more source

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