Results 61 to 70 of about 109,441 (301)

Magnetic ordering above room temperature in the sigma-phase of Fe66V34 [PDF]

open access: yes, 2008
Magnetic properties of four sigma-phase Fe_(100-x)V_x samples with 34 ...
Benilde F.O. Costa   +29 more
core   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Effect of Mn on σ Phase and Toughness of 22%Cr Duplex Stainless Steel by Aging Treatment at 700℃

open access: yesCailiao gongcheng, 2017
The effect of different Mn contents on the σ phase and toughness of 22%Cr (mass fraction, the same below) low-nickel DSS by means of OM, XRD, SEM, TEM, precipitation kinetics and Charpy impact tests was studied.
BAI Yu-liang   +4 more
doaj   +1 more source

How Do Quasicrystals Grow?

open access: yes, 2010
Using molecular simulations, we show that the aperiodic growth of quasicrystals is controlled by the ability of the growing quasicrystal `nucleus' to incorporate kinetically trapped atoms into the solid phase with minimal rearrangement.
Aaron S. Keys   +3 more
core   +1 more source

The role of interstitial binding in radiation induced segregation in W-Re alloys [PDF]

open access: yes, 2016
Due to their high strength and advantageous high-temperature properties, tungsten-based alloys are being considered as plasma-facing candidate materials in fusion devices.
Jaime Marian   +4 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Self-Assembly of Monatomic Complex Crystals and Quasicrystals with a Double-Well Interaction Potential

open access: yes, 2007
For the study of crystal formation and dynamics we introduce a simple two-dimensional monatomic model system with a parametrized interaction potential.
C. Janot   +5 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Creep-coordinated behaviors of the σ phase with stacking disordering defects in a Ni-based single crystal superalloy

open access: yesMaterials & Design
Ni-based single crystal superalloys (Ni-SXs) generally precipitate unfavorable topologically close-packed (TCP) phases at elevated temperatures. Conventional design strategies primarily aim to suppress TCP phase formation; however, this approach often ...
Tianyu Zhang   +11 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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