Results 41 to 50 of about 110,583 (215)

In-situ study of σ phase evolution in 25Cr-7Ni duplex stainless steel (DSS): Unrevealing critical insight

open access: yesMaterials & Design
The current understanding of the formation mechanism and kinetics of the σ phase in DSS remains ambiguous. This study investigates the in-situ evolution of the σ phase in DSS through a multi-faceted approach.
Raj Narayan Hajra   +6 more
doaj   +1 more source

Improved creep resistance of 20Cr25NiNb heat resistant steels through grain boundary intermetallic precipitation strengthening

open access: yesJournal of Materials Research and Technology, 2023
The creep performance of 20Cr25NiNb austenitic steel through the addition of W, Mo, and B elements was investigated. W and Mo enhanced high temperature creep resistance primarily through solid solution strengthening σss and precipitation strengthening σp
Ming Shu   +7 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Effect of Mn on σ Phase and Toughness of 22%Cr Duplex Stainless Steel by Aging Treatment at 700℃

open access: yesCailiao gongcheng, 2017
The effect of different Mn contents on the σ phase and toughness of 22%Cr (mass fraction, the same below) low-nickel DSS by means of OM, XRD, SEM, TEM, precipitation kinetics and Charpy impact tests was studied.
BAI Yu-liang   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Σ-Δ modulation analysis and optimization in fractional-N frequency synthesizer

open access: yesDianzi Jishu Yingyong, 2018
Analyzed the impaction of Σ-Δ modulation on Σ-Δ frequency synthesizer′s phase noise and spurs, and optimized Σ-Δ modulator to improve the performance of Σ-Δ frequency synthesizer.
Yang Jianming
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Creep-coordinated behaviors of the σ phase with stacking disordering defects in a Ni-based single crystal superalloy

open access: yesMaterials & Design
Ni-based single crystal superalloys (Ni-SXs) generally precipitate unfavorable topologically close-packed (TCP) phases at elevated temperatures. Conventional design strategies primarily aim to suppress TCP phase formation; however, this approach often ...
Tianyu Zhang   +11 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The Effect of Yttrium Addition on the Solidification Microstructure and Sigma Phase Precipitation Behavior of S32654 Super Austenitic Stainless Steel

open access: yesMetals
This study focuses on S32654 super austenitic stainless steel (SASS) and systematically characterizes the morphology of the sigma (σ) phase and the segregation behavior of alloying elements in its as-cast microstructure.
Jun Xiao   +6 more
doaj   +1 more source

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