Results 41 to 50 of about 1,323,588 (158)
RAS/ERK和PI3K/Akt串线信号网络的敏感性分析研究
四川大学学报. 自然科学版, 2012 建立了一个包含RAS/ERK(extracellular signal-regulated kinase)和PI3K/Akt信号通路的生化反应网络,采用基于LHS(Latin Hypercube sampling)抽样的多参数敏感性分析方法计算了网络参数变化对于ERK活化的影响,分析了PI3K/Akt信号通路的引入对RAS/ERK信号通路敏感性分布的影响.研究结果表明,K14,K17,K21,Km23,V26,Km27,K29',K31,K33',K37',K42',Kcat43,K46'Km52 ...
董珂, 文艳君
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Rare Metals, Volume 45, Issue 5, May 2026.ABSTRACT The efficacy of immunotherapy in triple‐negative breast cancer (TNBC) is often limited, whereas the immunotherapeutic potential of pyroptosis is frequently undermined by a compensatory surge in mitophagy. To address this challenge, this study developed a reactive oxygen species (ROS)‐responsive and mitochondria‐targeted nanomicelle (POM@CTT ...
Qingqing Dou +6 more
wiley +1 more source
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
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部分協調可能な符号器を有する一般多重アクセス通信路の通信路容量域 [PDF]
, 2015 電気通信大学2014スマートフォンやタブレット型PC の流行によって，遅延が少なく高い処理能力を持つ無線デバイスへの要求が急速に増加している．この要求を達成するために遅延を抑制する高効率の符号化法が必要である．高効率の符号化法を実現するために，複数の送信ノード間で協調して情報伝送を行う方法がある．送信ノード間で協調を行うことによって，理論上は伝送レートが向上することが知られている．無線技術の発展によって，このようなノード間協調が可能となりつつある．各携帯端末から共通の基地局への通信のように ...
ムラコシ, アヤト, 村越, 礼門
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International Journal of Applied Linguistics, Volume 36, Issue 1, Page 714-724, February 2026.ABSTRACT Interlingual translation, as defined by Roman Jakobson, refers to the transfer of meaning between languages. However, this concept has often been conflated with linguistic shifts between distinct cultures and nation‐states. To challenge this misconception, I propose the concept of self‐consumption translation (SCT), a subfield of interlingual ...
Bilin (Belen) Liu
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2016 目的研究过表达miRNA-291b-3p对诱导H9C2细胞胰岛素抵抗的影响。方法 1用10ng/ml TNF-α处理心肌细胞系H9C2细胞24h,通过Real time PCR检测miR-291b-3p表达水平,Western blot分析AKT/GSK信号通路活性,用蒽酮法检测细胞糖原水平;2构建miR-291b-3p mimics腺病毒载体,感染H9C2细胞48h,分析miR-291b-3p水平、AKT/GSK信号通路活性和糖原水平的变化。结果 1TNF-α处理H9C2细胞24h,miR-291b ...
隋小芳 +6 more
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SWEET1‐mediated glucose transport is crucial for energy availability in Arabidopsis
New Phytologist, Volume 249, Issue 4, Page 1816-1830, February 2026.Summary The stress‐responsive hormone abscisic acid (ABA) is known for its inhibitory effects on various physiological processes, including seed germination, often resulting in energy deprivation. Interestingly, ABA‐induced germination inhibition can be alleviated by exogenous glucose (Glc), mimicking a functional interplay between ABA and sugar ...
Xueyi Xue +3 more
wiley +1 more source
, 2011 目的:对非洲爪蟾BAFF和BAFF信号通路相关基因进行了分析。方法:采用生物信息学方法对两栖类重要的模式生物-非洲爪蟾的基因组和EST数据库进行分析。结果:非洲爪蟾BAFF cDNA全长为557 bp,编码218个氨基酸。与人BAFF序列相似性为37.5%。该文一共得到了14个BAFF信号通路相关基因。通过与人BAFF信号通路进行比较,对非洲爪蟾这14个BAFF信号通路相关基因进行了分析。结论:BAFF和BAFF信号通路在进化过程中较为保守 ...
王爱民 +7 more
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International Journal of Urban and Regional Research, Volume 50, Issue 1, Page 191-220, January 2026.Abstract Henry George advocated for capturing land value increases for public ends. The active approach of public authorities organizing and financing land development can help capture higher land value increases, as Hartman and Spit indicate. However, this approach hardly happens in developing countries, where the coalition of private developers and ...
Nannan Xu
wiley +1 more source
Gaoya dianqi, 2003 介绍了以计算机为核心的绝缘在线监测系统的程控多路选通装置的基本原理、设计方法、试验结果和实际应用实例。该装置与计算机并行通讯,由计算机发出程序控制信号来选通所需要的任何输入通道,可实现256路信号选4路的功能,能够满足大中型变电站中对所有高压电气设备的绝缘状况进行在线巡回监测的需要。这种多路选通装置还可应用于其他多信号的巡回监测系统中。
蒋玉红 +3 more
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