Results 21 to 30 of about 1,323,588 (158)
ABSTRACT Biomass‐based hydrogels are widely regarded as ideal substrates for self‐powered wearable sensors. However, the practical applications of hydrogels are commonly limited by their inherent low strength and toughness, which restrict their capacity to withstand repeated stretching, bending and other mechanical loads arising from human motion in ...
Boyu Du +9 more
wiley +1 more source
Behavioral interventions to reduce demand for threatened freshwater turtles as pets
Abstract Growing demand for freshwater turtles as pets has fueled illegal trade and accelerated wild population declines, underscoring the need for theory‐based demand‐reduction interventions. We conducted a three‐part randomized controlled trial with active turtle keepers (n = 1800) in China to test conservation‐ and legality‐framed messages by ...
Wuji Zheng +9 more
wiley +1 more source
ABSTRACT Epidermal bioelectronics is a transformative technology for continuous health monitoring and human‐computer interaction. However, the mechanical and physiological mismatch at the skin–device interface limits its long‐term application. Electrospun nanofiber membranes (ENMs), with their unique three‐dimensional hierarchical porous network and ...
Jiahua Ni +7 more
wiley +1 more source
ABSTRACT The regeneration of osteoporotic bone defects is severely hampered by compromised endogenous healing capacity, demanding advanced strategies that actively orchestrate pro‐osteogenic microenvironments. Here, we report an integrated, self‐powered osteo‐regenerative system that uniquely leverages a dual ultrasound‐responsive piezoelectric ...
Bing Tan +6 more
wiley +1 more source
ABSTRACT The healing of diabetic chronic wounds is hindered by multiple pathological barriers, including oxidative stress imbalance induced by hyperglycemia, persistent bacterial infection, and impaired neovascular function. This study developed an F127–HA–BiOCl@CeO2 (FHBC) hydrogel dressing with acoustic responsiveness, achieving tissue repair through
Ran Zhao +8 more
wiley +1 more source
ABSTRACT In conventional photoconductive detectors, the shared collection path for dark current and photocurrent imposes a fundamental compromise between noise suppression and signal responsivity. To break this trade‐off, we introduce a device architecture featuring a strategically integrated third electrode within a MAPbI3/Nb2CTx heterostructure. This
Yan‐Wei Lv +7 more
wiley +1 more source
急性呼吸窘迫综合征(ARDS)是一种进行性缺氧性呼吸衰竭的危重症疾病。目前ARDS的发病机制在很大程度上仍然不明,但越来越多的证据表明多种信号通路及相关的蛋白可调节急性肺损伤的炎症反应。参与ARDS潜在的信号通路可能包括PI3K/Akt/mTOR信号通路、p38MAPK和ERK信号通路、TLR信号通路、STAT3信号通路、Wnt/
郭龙, 张春媚, 高勇, 赵忠岩
doaj
糖尿病肾病是常见的糖尿病微血管并发症,也是糖尿病患者死亡的主要原因之一。铁死亡是一种铁依赖性调节性细胞死亡,其在糖尿病肾病的发生发展中具有一定作用。腺苷一磷酸活化的蛋白质激酶(AMPK)介导的铁死亡相关信号通路可以延缓糖尿病肾病的进程,但AMPK信号过度激活可能会诱导细胞发生自噬性死亡;激活核转录因子红系2相关因子(Nrf)2和血红素加氧酶(HO)-1介导的信号通路能够抑制细胞铁死亡并改善糖尿病肾病,但HO-1在铁死亡中的调节作用是双向的,激活HIF-1α/HO-1信号通路可能导致细胞内铁过载 ...
刘 攀, 张 正东, 陈 秋
doaj +1 more source
ABSTRACT Bio‐inspired artificial vision systems have made significant progress, but most focus on photo‐receptors, neglecting the hardware implementation of the efficient downstream neural circuits for complex computations like motion detection. To overcome this bottleneck, we demonstrate a neuromorphic vision system that mimics Drosophila's motion ...
Xianyu Hu +4 more
wiley +1 more source
近年来的研究发现 ,Wnt β catenin信号通路与肿瘤侵袭转移的相关事件如癌细胞的迁移粘附、细胞外基质的降解及肿瘤的血管生成密切相关。Wnt信号还能激活Wnt Ca2 + 、Wnt JNK等非正规通路 ,与人类肿瘤的侵袭转移也有一定关系。另外 ,Wnt通路还可通过与细胞内其他信号通路如K ras、RTK及ILK介导的信号通路相互作用 ,在肿瘤侵袭转移过程中起重要作用国家自然科学基金资助项目 ( 3 0 170 463
蔡秋凤, 欧阳高亮
core

