Results 21 to 30 of about 1,334,557 (181)
Zhongguo shiyan zhenduanxue, 2023 目的 基于微阵列数据分析筛选中国人冠心病(CHD)的关键基因和信号通路，以期为临床探究潜在的发病机制与治疗靶点。方法 以CHD为检索关键词从基因表达图谱(GEO)数据库下载GSE71226微阵列芯片数据进行进一步分析，利用R Studio软件中“limma”包筛选冠心病患者与正常健康人群的差异基因并对其进行可视化处理，利用R Studio软件中“clusterProfiler”包和“org.Hs.eg.db”包对差异基因进行基因本体(GO)功能富集分析和京都基因与基因组百科全书(KEGG)通路富集分析 ...
王星 +5 more
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肿瘤免疫微环境中cGAS-STING信号通路的细胞间信号传递
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences环鸟苷酸-腺苷酸合成酶（cGAS）-干扰素基因刺激因子（STING）信号通路是肿瘤免疫治疗中备受关注的靶点。模式识别受体cGAS识别胞质双链DNA（dsDNA），生成第二信使2´3´-环鸟苷酸-腺苷酸（cGAMP），活化接头蛋白STING，介导干扰素和促炎性细胞因子的产生，从而促进肿瘤免疫。肿瘤免疫微环境中cGAS-STING通路的细胞间信号传递维持并增强天然免疫应答，推动适应性免疫的发展。基于膜系统的细胞外囊泡运输、吞噬作用和细胞膜融合传递dsDNA、cGAMP以及活化的STING蛋白 ...
Meng-Qiu Wang, Ping-Long Xu, Qi-Rou Wu
semanticscholar +1 more source
電力線搬送通信信号が誘導によりVDSL通信に与える影響の研究 [PDF]
, 2006 電力線搬送通信(PLC)は家庭内の配電線を通信線としても利用するため,新たに通信線を配線する必要がないといった利点があるが,通信目的として設計されていない電力線を使用するため,他の通信-の影響を検討する必要がある.通信に影響を及ぼす経路としては放射,伝導,誘導によるものが考えられるが,本論文では,通信線に誘導したPLC信号が同じ周波数帯域を使用するVDSL通信へ与える影響について検討を行った.まず,電力線から通信線に誘導する電圧を ...
クワバラ, ノブオ +13 more
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Rare Metals, Volume 45, Issue 10, October 2026.ABSTRACT Biomass‐based hydrogels are widely regarded as ideal substrates for self‐powered wearable sensors. However, the practical applications of hydrogels are commonly limited by their inherent low strength and toughness, which restrict their capacity to withstand repeated stretching, bending and other mechanical loads arising from human motion in ...
Boyu Du +9 more
wiley +1 more source
Behavioral interventions to reduce demand for threatened freshwater turtles as pets
Conservation Biology, Volume 40, Issue 5, October 2026.Abstract Growing demand for freshwater turtles as pets has fueled illegal trade and accelerated wild population declines, underscoring the need for theory‐based demand‐reduction interventions. We conducted a three‐part randomized controlled trial with active turtle keepers (n = 1800) in China to test conservation‐ and legality‐framed messages by ...
Wuji Zheng +9 more
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Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Epidermal bioelectronics is a transformative technology for continuous health monitoring and human‐computer interaction. However, the mechanical and physiological mismatch at the skin–device interface limits its long‐term application. Electrospun nanofiber membranes (ENMs), with their unique three‐dimensional hierarchical porous network and ...
Jiahua Ni +7 more
wiley +1 more source
Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT The regeneration of osteoporotic bone defects is severely hampered by compromised endogenous healing capacity, demanding advanced strategies that actively orchestrate pro‐osteogenic microenvironments. Here, we report an integrated, self‐powered osteo‐regenerative system that uniquely leverages a dual ultrasound‐responsive piezoelectric ...
Bing Tan +6 more
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Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT The healing of diabetic chronic wounds is hindered by multiple pathological barriers, including oxidative stress imbalance induced by hyperglycemia, persistent bacterial infection, and impaired neovascular function. This study developed an F127–HA–BiOCl@CeO2 (FHBC) hydrogel dressing with acoustic responsiveness, achieving tissue repair through
Ran Zhao +8 more
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Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT In conventional photoconductive detectors, the shared collection path for dark current and photocurrent imposes a fundamental compromise between noise suppression and signal responsivity. To break this trade‐off, we introduce a device architecture featuring a strategically integrated third electrode within a MAPbI3/Nb2CTx heterostructure. This
Yan‐Wei Lv +7 more
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Zhongguo shiyan zhenduanxue, 2017 急性呼吸窘迫综合征（ARDS）是一种进行性缺氧性呼吸衰竭的危重症疾病。目前ARDS的发病机制在很大程度上仍然不明,但越来越多的证据表明多种信号通路及相关的蛋白可调节急性肺损伤的炎症反应。参与ARDS潜在的信号通路可能包括PI3K/Akt/mTOR信号通路、p38MAPK和ERK信号通路、TLR信号通路、STAT3信号通路、Wnt/
郭龙, 张春媚, 高勇, 赵忠岩
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