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Veterinary Dermatology, Volume 35, Issue 1, Page 5-14, February 2024.Background – Canine atopic dermatitis (AD) is a complex inflammatory skin disease associated with cutaneous microbiome, immunological and skin barrier alterations. This review summarises the current evidence on skin barrier defects and on cutaneous microbiome dysfunction in canine AD.
Domenico Santoro +13 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2000 肿瘤的免疫治疗是治疗肿瘤的新方法,它通过增强肿瘤抗原或肿瘤相关抗原的免疫原性, 诱导机体产生肿瘤特 异性的免疫应答反应而杀伤肿瘤细胞。本系列研究采用同源重组方法构建了表达人癌胚抗原( carcino embryonic antigen, CEA)的重组痘苗病毒, 经动物实验证明了其具有强免疫原性、安全性和防治 CEA 阳性肿瘤的可靠性。
罗超权 +5 more
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Cost-effectiveness of PD-L1 testing to guide immunotherapy for patients with non-small cell lung cancer in China [PDF]
Background and purpose: According to the latest data from the National Cancer Center, the incidence rate and mortality of lung cancer in China rank first among all malignant tumors, and 85% are non-small cell lung cancer (NSCLC).
LI Yuan, GUO Lingchuan, YUAN Yong, ZHENG Qiang, JIN Yan, MING Jian
core +1 more source
Strategy of Targeted T Cell Immunotherapy for Acute Myeloid Leukemia [PDF]
T cell dysfunction is a common feature in patients with acute myeloid leukemia (AML). The up-regulation of immune checkpoint (IC) proteins resulting in T cell exhaustion is a key reason for T cell dysfunction.
LI Yangqiu
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特异性免疫治疗对变应性鼻炎外周血ＣＤ４＋ ＣＤ２５＋Ｔ调节细胞的影响及远期疗效的观察
Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 通过检测变应性鼻炎患者皮下特异性免疫治疗前后外周血ＣＤ４＋Ｔ淋巴细胞表面ＣＤ２５表达情况的变化及观察相关指标，探讨皮下特异性免疫治疗的机制，评价其远期疗效。【方法】 将９０例确诊变应性鼻炎患者随机分为免疫治疗组和药物治疗组，每组４５例。通过症状评分、使用药物评分和鼻结膜炎相关生活质量调查问卷等评价临床疗效，同时通过流式细胞仪检测外周血ＣＤ４＋Ｔ淋巴细胞表面ＣＤ２５表达情况。【结果】 随着特异性免疫治疗的进行，免疫治疗组与药物治疗组症状评分无统计学差异；而免疫治疗组药物评分要明显低于药物治疗组 ...
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Current status and future prospects of clinical trials for radioiodine-refractory thyroid cancer [PDF]
Radioiodine-refractory thyroid cancer (RAIR-TC) refers to thyroid cancer that is unable to or difficult to benefit from 131I treatment. The type of RAIR-TC we commonly encounter is differentiated thyroid cancer (DTC), which is originally well ...
LI Ruping, YANG Hui
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Linchuang shenzangbing zazhi, 2016 狼疮性肾炎(lupus nephritis,LN)是系统性红斑狼疮(systemic lupus erythematosus,SLE)累及肾脏的常见且严重的并发症之一,若治疗不当,最终会进展为终末期肾脏疾病,需行肾脏替代治疗。因此,早期发现、早期诊断LN,并积极进行药物干预,从而延缓其进展是治疗的关键。LN的治疗包括药物治疗、非药物治疗,前者包括糖皮质激素(glucocorticoids,GC)、免疫抑制剂、生物制剂和中药治疗,后者包括手术、肾脏替代治疗 ...
娄美玉, 陈文莉
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Detection of PD-L1 protein in circulating tumor cells of Non Small Cell Lung Cancer [PDF]
, 2017 背景现状及研究的目的意义 目前，肺癌位居全世界死亡率和发病率很高的恶性肿瘤之一。按病理组织学，分为小细胞肺癌（smallcelllungcancer，SCLC）和非小细胞肺癌（nonsmallcelllungcancer，NSCLC），其中大约80%是NSCLC。由于NSCLC早期的临床症状和体征不明显，大概2/3的NSCLC患者在确诊时就已经失去手术根治的机会。由于传统的化疗药物和放疗治疗不能获得很好的疗效，NSCLC自诊断之后的5年生存率只有10%-15 ...
吴晓婷
core
Immunotherapy for Advanced Non-small Cell Lung Cancer: Research Progress and Perspectives [PDF]
Immunotherapy has changed the treatment landscape of advanced non-small cell lung cancer (NSCLC), showing great potential in the treatment of untreated and relapsed or refractory (R/R) patients.
Jingyi WANG, Lin WU, Yuling ZHONG
core +1 more source
Zhongguo shiyan zhenduanxue, 2011 胃癌是我国常见的恶性肿瘤,全世界35%胃癌发生在中国,年发病30多万,年胃癌死亡超过26万。免疫治疗可通过直接抑制肿瘤细胞及增强机体免疫功能等作用治疗肿瘤 ...
冯燕, 全吉钟, 王冬旭, 吕晓鹏
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