Results 41 to 50 of about 14,135 (164)
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 【目的】探讨变应性鼻炎患者特异性免疫治疗(SIT)效果及其在防治支气管哮喘中的意义。【方法】对167 例螨过敏的持续性变应性鼻炎患者, 进行免疫治疗, 检测各治疗时期患者血清总免疫球蛋白 E (TIgE)、特异性免疫球蛋白 E (SIgE)和嗜酸性粒细胞阳离子蛋白(ECP)浓度, 并评估其过敏症状的变化。【结果】变应性鼻炎特异性免疫治疗后症状改善( P< 0.01) ; 儿童变应性鼻炎 SIT 效果较成人好( P< 0.01) 。此外, 观察期满 3 年的 49 例接受系统免疫治疗的患者与未系统治疗患者
瞿申红 +5 more
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Progress in the development of mRNA vaccine and its delivery systems for anti-tumor immunotherapy [PDF]
Due to the drawbacks of low specificity and high risk of side effects of traditional anti-tumor treatments in clinical practice, novel anti-tumor immunotherapy has received attention and has been gradually applied.
XIN Meiyi, LIN Yuhong, ZHAO Kai
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Veterinary Dermatology, Volume 36, Issue 4, Page 443-452, August 2025.Background – Allergen immunotherapy is used as aetiological treatment for canine atopic dermatitis (cAD). Objective – To assess the anti‐inflammatory agent‐sparing effect over 1 year of immunotherapy using pullulan‐conjugated recombinant Der f 2 (rDf2‐P). Conclusions and Clinical Relevance – Der f 2‐P immunotherapy can lead to a rapid reduction in anti‐
Masahiko Nagata +7 more
wiley +1 more source
Zhongguo shiyan zhenduanxue免疫治疗是小细胞肺癌（small cell lung cancer，SCLC）的重要治疗手段之一，极大改善患者的预后。但由于治疗期间出现迅速耐药，导致很大一部分患者无法从中受益。本文总结了针对SCLC免疫治疗中产生耐药性的关键分子机制的最新研究，包括PD-L1表达缺失、抗原呈递受损、T细胞本身缺乏和浸润受限、PI3K/AKT信号通路的激活、基因组损伤和克隆多样性爆发等。我们还探索了对免疫治疗耐药后进展的策略，包括免疫治疗再挑战的可能、联合放疗、联合抗血管生成药物及其他可能疗法 ...
李美, 翟旭杰, 范勃, 白元松
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Current status and future prospects of clinical trials for radioiodine-refractory thyroid cancer [PDF]
Radioiodine-refractory thyroid cancer (RAIR-TC) refers to thyroid cancer that is unable to or difficult to benefit from 131I treatment. The type of RAIR-TC we commonly encounter is differentiated thyroid cancer (DTC), which is originally well ...
LI Ruping, YANG Hui
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, 2018 近年来,随着肝细胞癌基础研究不断深入,分子靶向药物及免疫治疗药物的临床开发及应用为肝细胞癌的治疗带来了新的突破。肝细胞癌的靶向治疗药物具有较高的特异性,能够选择性地杀伤肿瘤细胞,尽可能减少对正常组织的损伤。目前,这些靶向治疗药物主要分为小分子靶向药物、肝细胞癌抗原特异性靶向药物和免疫检验点靶向药物3类 ...
邱盛萍, 黄承浩
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Veterinary Dermatology, Volume 36, Issue 4, Page 453-461, August 2025.Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Wendie Roldan Villalobos +5 more
wiley +1 more source
Cancer Innovation, Volume 3, Issue 6, December 2024.This study developed a NCC‐BC‐A scale with relatively high validity and reliability for breast cancer (BC) patients. NCC‐BC‐A scale fully considered the characteristics of systemic treatment status for BC and the realistic situation in China, which may help clinicians to pay more attention to QOL of BC patients and to optimize management system for BC.
Fei Ma +4 more
wiley +1 more source
Veterinary Dermatology, Volume 35, Issue 6, Page 736-744, December 2024.Background – Topical therapy is preferred for otitis externa (OE) in dogs, and otic products commonly contain glucocorticoids that can be systemically absorbed and possibly interfere with diagnostic tests such as intradermal testing (IDT). Hypothesis/Objectives – To determine the effect of a long‐lasting otic solution containing mometasone furoate (MF)
Jennifer L. Clegg +2 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2014 化疗是卵巢癌综合治疗的一个重要组成部分,是晚期和复发性卵巢癌的主要治疗手段,在控制腹水和预防复发的同时也会对机体产生一些不良反应,如骨髓及免疫功能抑制等,影响了患者治疗的依从性。本文通过观察43例卵巢上皮性癌患者首次化疗期间机体免疫功能的变化 ...
杨均
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