Results 61 to 70 of about 14,135 (164)
Research progress of m6A methylation modification in regulating tumor immunity [PDF]
N6-methyladenosine (m6A) is the most prevalent modification that regulates gene expression in eukaryotes. It regulates splicing, degradation, stability, and translation of RNA.
ZHANG Jing, ZHOU Haixia
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Pharmacology of drugs used in autoimmune dermatopathies in cats and dogs: A narrative review
Veterinary Dermatology, Volume 35, Issue 4, Page 453-476, August 2024.Immunosuppressive drugs are the mainstay of treatment for many feline and canine autoimmune skin diseases, either as monotherapy or in combination with other drugs. Treatment with these drugs is often lifelong and may have long‐term consequences on the affected animal's overall quality of life.
Heng L. Tham, Jennifer L. Davis
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Preliminary study of radioiodinated anti-ICAM-1 monoclonal antibody for the diagnosis and treatment of triple negative breast cancer [PDF]
, 2017 癌症已经成为全世界人类的最大致死原因，乳腺癌是目前女性最常见的恶性肿瘤之一，发生于上皮组织，发病率位居女性恶性肿瘤之首，全世界数百万妇女遭受着乳腺癌的折磨。乳腺癌是高度异质性的疾病，不同分子亚型的乳腺癌，其临床表现、预后和治疗效果都不尽相同。三阴性乳腺癌（TNBC）是一类特殊的乳腺癌，其雌激素受体（ER），孕激素受体（PR）和人表皮生长因子受体2（HER-2）的表达阴性，同样也是一种分子异质性疾病。TNBC恶性程度高、易转移，加上缺乏针对性的治疗方案和特定的分子靶点 ...
尤林怡
core
Progress of Targeted Therapy and Immunotherapy for Gastric Cancer [PDF]
Gastric cancer (GC) is a common malignant tumor of the digestive tract in China. It is characterized by high morbidity, mortality, and proportion of patients in advanced stages.
PAN Hongming, ZHENG Yu
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特异性免疫治疗对变应性鼻炎外周血ＣＤ４＋ ＣＤ２５＋Ｔ调节细胞的影响及远期疗效的观察
Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 通过检测变应性鼻炎患者皮下特异性免疫治疗前后外周血ＣＤ４＋Ｔ淋巴细胞表面ＣＤ２５表达情况的变化及观察相关指标，探讨皮下特异性免疫治疗的机制，评价其远期疗效。【方法】 将９０例确诊变应性鼻炎患者随机分为免疫治疗组和药物治疗组，每组４５例。通过症状评分、使用药物评分和鼻结膜炎相关生活质量调查问卷等评价临床疗效，同时通过流式细胞仪检测外周血ＣＤ４＋Ｔ淋巴细胞表面ＣＤ２５表达情况。【结果】 随着特异性免疫治疗的进行，免疫治疗组与药物治疗组症状评分无统计学差异；而免疫治疗组药物评分要明显低于药物治疗组 ...
doaj
Zhongguo aizheng zazhi, 2021 <正>溶瘤病毒是一类能选择性地感染并杀死肿瘤细胞而不损伤正常细胞的天然或重组病毒[1]。与传统免疫治疗相比,溶瘤病毒治疗具有靶向性好、不良反应小、杀伤肿瘤途径多、不易产生耐药性等优势。多项临床研究[2-3]显示,溶瘤病毒可为不同类型、不同进展阶段,甚至转移性和无法治愈的肿瘤患者带来临床获益。更重要的是,其与化疗、放疗、免疫治疗等联合应用时,
许 青 +12 more
doaj
Current status and prospects of immunotherapy for locally advanced nasopharyngeal carcinoma [PDF]
Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma arising from the nasopharyngeal epithelium, which is associated with Epstein-Barr virus (EBV) infection and is most common in southern China.
LIU Xixi, SUN Yajie, YANG Kunyu
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Linchuang shenzangbing zazhi, 2016 狼疮性肾炎(lupus nephritis,LN)是系统性红斑狼疮(systemic lupus erythematosus,SLE)累及肾脏的常见且严重的并发症之一,若治疗不当,最终会进展为终末期肾脏疾病,需行肾脏替代治疗。因此,早期发现、早期诊断LN,并积极进行药物干预,从而延缓其进展是治疗的关键。LN的治疗包括药物治疗、非药物治疗,前者包括糖皮质激素(glucocorticoids,GC)、免疫抑制剂、生物制剂和中药治疗,后者包括手术、肾脏替代治疗 ...
娄美玉, 陈文莉
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Zhongguo shiyan zhenduanxue, 2011 胃癌是我国常见的恶性肿瘤,全世界35%胃癌发生在中国,年发病30多万,年胃癌死亡超过26万。免疫治疗可通过直接抑制肿瘤细胞及增强机体免疫功能等作用治疗肿瘤 ...
冯燕, 全吉钟, 王冬旭, 吕晓鹏
doaj
Immunotherapy for Advanced Non-small Cell Lung Cancer: Research Progress and Perspectives [PDF]
Immunotherapy has changed the treatment landscape of advanced non-small cell lung cancer (NSCLC), showing great potential in the treatment of untreated and relapsed or refractory (R/R) patients.
Jingyi WANG, Lin WU, Yuling ZHONG
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