Results 51 to 60 of about 14,135 (164)
An exploratory study on the perioperative treatment of locally advanced gastric cancer with combination of penpulimab, anlotinib and chemotherapy [PDF]
Background and purpose: There is a consensus within the medical community regarding the perioperative treatment of locally advanced gastric cancer (LAGC), yet the selection of an efficient and safe treatment strategy remains a contentious issue. Previous
LIU Shuai, ZHANG Kai, ZHANG Xiaoqing, LUAN Wei
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Veterinary Dermatology, Volume 35, Issue 6, Page 652-661, December 2024.Background – Mycophenolate is an immunomodulating agent successfully used for the treatment of moderate‐to‐severe atopic dermatitis (AD) in people. Mycophenolate is an effective steroid‐sparing treatment option for use in dogs with inflammatory skin diseases.
Michael Klotsman +5 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2017 目的研究异体CIK联合血浆置换临床治疗肝癌的效应和机制。方法分离健康人外周血单个核细胞（PBMC）,加入细胞因子诱导成CIK细胞,体外培养扩增。病例均给予内科综合支持治疗情况下,随机分为异体CIK细胞治疗组和异体CIK+血浆置换治疗组。应用ELISA法比较二组治疗前后血浆中IFN-γ、IL-4、IL-10、TGF-β、VEGF的浓度变化;流式细胞术检测二组治疗前后患者外周血中CD3+和CD4+细胞比例、CD4+/CD8+比值、CD8+细胞比例;比较二组患者的生存质量、无进展生存期（PFS）、总生存期 ...
侯俊杰 +7 more
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Rare Metals, Volume 43, Issue 11, Page 6006-6022, November 2024.Graphical abstract AbstractCisplatin resistance is the main cause for the failure of cancer therapy. To solve the problem, we proposed to develop a novel human serum albumin (HSA) nanoplatform to integrate chemotherapy, photothermal therapy (PTT) and immunotherapy.
Xue‐Yu Man +7 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2019 中枢神经自身免疫病是自身免疫异常导致神经系统损害的疾病。这类疾病发病机制不明，临床表现多样，治疗手段单一，最终结局各异，目前诊治面临巨大挑战。随着大数据技术、基因、蛋白组学及影像学新技术的发展，对特定疾病寻找个体化生物标记，寻找治疗新靶点，最终实现精确诊断和个体化治疗逐渐成为可能。本文将结合课题组已开展的工作，探讨中枢神经自身免疫病的精确诊断和治疗。
邱伟
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浙江大学学报. 医学版由于缺乏有效的治疗手段，复发转移仍然是乳腺癌患者死亡的主要原因。在转移发生之前，远处器官内已经形成了适合乳腺癌细胞生长的微环境——转移前生态位（PMN）。髓源性抑制细胞（MDSC）是一类具有免疫抑制作用的异质性未成熟髓系细胞群，可在乳腺癌患者体内大量扩增，参与PMN的形成。MDSC不仅支持乳腺癌细胞免疫逃逸，而且还可通过重塑肺血管内皮细胞外基质、招募癌症干细胞来促进乳腺癌转移的发生。此外，MDSC还能通过削弱免疫疗法的抗肿瘤效率来降低药物的治疗效果。因此 ...
杜 楠楠 +4 more
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Recent Advances and Hot Spots of Neoadjuvant Immunotherapy Combined with Chemotherapy for Esophageal Carcinoma [PDF]
Surgery-based multidisciplinary comprehensive treatment is the preferred treatment strategy for local advanced esophageal cancer. Neoadjuvant chemotherapy and neoadjuvant chemoradiotherapy have been recommended by the Chinese Society of Clinical Oncology
Chunyue GAI +8 more
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Veterinary Dermatology, Volume 35, Issue 4, Page 375-385, August 2024.Background – Perianal fistulas are painful ulcers or sinus tracts that disproportionately affect German shepherd dogs and are proposed as a spontaneous animal model of fistulising Crohn's disease. Objectives – To characterise the rectal and cutaneous microbiota in German shepherd dogs with perianal fistulas and to investigate longitudinal shifts with ...
Christine L. Cain +6 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2000 肿瘤的免疫治疗是治疗肿瘤的新方法,它通过增强肿瘤抗原或肿瘤相关抗原的免疫原性, 诱导机体产生肿瘤特 异性的免疫应答反应而杀伤肿瘤细胞。本系列研究采用同源重组方法构建了表达人癌胚抗原( carcino embryonic antigen, CEA)的重组痘苗病毒, 经动物实验证明了其具有强免疫原性、安全性和防治 CEA 阳性肿瘤的可靠性。
罗超权 +5 more
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Detection of MTAP Protein and Gene Expression in Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective The abnormal expression of MTAP, a tumor suppressor gene, is found in a variety of tumor tissues. The aim of this study is to detect the expression of MTAP mRNA protein and the clinical significance for the therapy of non-small ...
Baoqing DING +3 more
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