Results 31 to 40 of about 14,135 (164)
Evaluation of short⁃term efficacy of precision immunotherapy in prostate cancer patients and construction of a personalized prediction model based on PD⁃L1/TMB [PDF]
Objective To evaluate the short⁃term efficacy of programmed death⁃ligand 1（PD⁃L1）inhibitors in patients with prostate cancer and to construct an individualized predictive model based on PD⁃L1 expression levels and tumor mutational burden（TMB）to predict ...
HUANG Yiming，CHEN Zhibin，LYU Tianbing，LI Xiaorong
core +2 more sources
New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu +8 more
wiley +1 more source
中西医结合护理, 2022 Objective To observe the effect of Tonifying deficiency and Zhengqi porridge on immune function reconstruction of HIV/AIDS patients with Qi deficiency.
WEI Yan (魏艳) +5 more
doaj +1 more source
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】探讨免疫抑制剂在肾移植术后巨细胞病毒( cytomegalovirus, CMV)病治疗中的应用情况。【方法】对 47 例肾移植术后 CM V 病患者治疗中免疫抑制剂的应用进行总结和分析。【结果】CMV 病治疗有效率 72%, 治愈率 66%。34 例( 72%)患者停用了皮质激素, 16 例( 34%)患者环孢素减量, 4 例( 9%)停用全部免疫抑制剂。【结论】肾移植术后CMV 病治疗中免疫抑制剂的调整应作为治疗的辅助措施 之一,适当减少甚至停用部分或全部免疫抑制剂并不增加排斥反应的发生率。
洪良庆
doaj
Zhongguo shiyan zhenduanxue, 2020 目的探讨自身免疫病病人外周血NK(CD3-CD16+CD56+)细胞在自身免疫病发病机制中的作用。方法用流式细胞术检测29例自身免疫病病人和18例健康对照者外周血NK(CD3-CD16+CD56+)细胞数,同时检测NK细胞的胞膜活化性受体NKG2D(CD314)和抑制性受体NKG2A(CD159)以及穿孔素、颗粒酶-β的表达。结果自身免疫病病人外周血NK细胞数与健康对照组无明显差别。自身免疫病病人NK细胞膜活化性受体NKG2D和颗粒酶-β的表达在治疗前和治疗后均低于正常对照组 ...
陈琳 +7 more
doaj
, 2016 中国科协生命科学学会联合体:免疫细胞在病原菌的清除中发挥关键作用。病原菌入侵免疫细胞后能引起免疫细胞的炎性坏死即细胞焦亡(pyroptosis),这是机体的重要免疫防御反应,在清除病原感染和内源危险信号中发挥重要作用。细胞焦亡由炎性蛋白酶caspase介导,但具体机制完全未知 ...
韩家淮
core
Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis +9 more
wiley +1 more source
Treatment Strategy and Research Progress of Immune Microenvironment for Liver Metastasis of Non-small Cell Lung Cancer [PDF]
Liver is the common site for metastasis and spread of non-small cell lung cancer (NSCLC). Lung cancer patients with liver metastasis have poor prognosis, which may be related to liver-specific microenvironment composition.
SUN Jiaqi, WANG Yudong
core +1 more source
Updated insights into the molecular pathogenesis of canine atopic dermatitis
Veterinary Dermatology, Volume 36, Issue 4, Page 375-384, August 2025.Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley +1 more source