Results 71 to 80 of about 14,254 (195)
Rare Metals, Volume 43, Issue 11, Page 6006-6022, November 2024.Graphical abstract AbstractCisplatin resistance is the main cause for the failure of cancer therapy. To solve the problem, we proposed to develop a novel human serum albumin (HSA) nanoplatform to integrate chemotherapy, photothermal therapy (PTT) and immunotherapy.
Xue‐Yu Man +7 more
wiley +1 more source
Veterinary Dermatology, Volume 35, Issue 4, Page 375-385, August 2024.Background – Perianal fistulas are painful ulcers or sinus tracts that disproportionately affect German shepherd dogs and are proposed as a spontaneous animal model of fistulising Crohn's disease. Objectives – To characterise the rectal and cutaneous microbiota in German shepherd dogs with perianal fistulas and to investigate longitudinal shifts with ...
Christine L. Cain +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2014 化疗是卵巢癌综合治疗的一个重要组成部分,是晚期和复发性卵巢癌的主要治疗手段,在控制腹水和预防复发的同时也会对机体产生一些不良反应,如骨髓及免疫功能抑制等,影响了患者治疗的依从性。本文通过观察43例卵巢上皮性癌患者首次化疗期间机体免疫功能的变化 ...
杨均
doaj
, 2016 中国科协生命科学学会联合体:免疫细胞在病原菌的清除中发挥关键作用。病原菌入侵免疫细胞后能引起免疫细胞的炎性坏死即细胞焦亡(pyroptosis),这是机体的重要免疫防御反应,在清除病原感染和内源危险信号中发挥重要作用。细胞焦亡由炎性蛋白酶caspase介导,但具体机制完全未知 ...
韩家淮
core
Current status and prospects of immunotherapy for locally advanced nasopharyngeal carcinoma [PDF]
Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma arising from the nasopharyngeal epithelium, which is associated with Epstein-Barr virus (EBV) infection and is most common in southern China.
LIU Xixi, SUN Yajie, YANG Kunyu
core +1 more source
Pharmacology of drugs used in autoimmune dermatopathies in cats and dogs: A narrative review
Veterinary Dermatology, Volume 35, Issue 4, Page 453-476, August 2024.Immunosuppressive drugs are the mainstay of treatment for many feline and canine autoimmune skin diseases, either as monotherapy or in combination with other drugs. Treatment with these drugs is often lifelong and may have long‐term consequences on the affected animal's overall quality of life.
Heng L. Tham, Jennifer L. Davis
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2017 目的研究异体CIK联合血浆置换临床治疗肝癌的效应和机制。方法分离健康人外周血单个核细胞（PBMC）,加入细胞因子诱导成CIK细胞,体外培养扩增。病例均给予内科综合支持治疗情况下,随机分为异体CIK细胞治疗组和异体CIK+血浆置换治疗组。应用ELISA法比较二组治疗前后血浆中IFN-γ、IL-4、IL-10、TGF-β、VEGF的浓度变化;流式细胞术检测二组治疗前后患者外周血中CD3+和CD4+细胞比例、CD4+/CD8+比值、CD8+细胞比例;比较二组患者的生存质量、无进展生存期（PFS）、总生存期 ...
侯俊杰 +7 more
doaj
Cost-effectiveness of PD-L1 testing to guide immunotherapy for patients with non-small cell lung cancer in China [PDF]
Background and purpose: According to the latest data from the National Cancer Center, the incidence rate and mortality of lung cancer in China rank first among all malignant tumors, and 85% are non-small cell lung cancer (NSCLC).
LI Yuan, GUO Lingchuan, YUAN Yong, ZHENG Qiang, JIN Yan, MING Jian
core +1 more source
Update on the role of cytokines and chemokines in canine atopic dermatitis
Veterinary Dermatology, Volume 35, Issue 1, Page 25-39, February 2024.Background – Cytokines and chemokines play central roles in the pathogenesis of canine atopic dermatitis (cAD). Numerous studies have been published and provide new insights into their roles in cAD. Objectives – To summarise the research updates on the role of cytokines and chemokines in the pathogenesis of cAD since the last review by the ...
Chie Tamamoto‐Mochizuki +6 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2019 中枢神经自身免疫病是自身免疫异常导致神经系统损害的疾病。这类疾病发病机制不明，临床表现多样，治疗手段单一，最终结局各异，目前诊治面临巨大挑战。随着大数据技术、基因、蛋白组学及影像学新技术的发展，对特定疾病寻找个体化生物标记，寻找治疗新靶点，最终实现精确诊断和个体化治疗逐渐成为可能。本文将结合课题组已开展的工作，探讨中枢神经自身免疫病的精确诊断和治疗。
邱伟
doaj