Results 61 to 70 of about 2,098 (100)

Fas RNA抑制前后缺血再灌注神经细胞凋亡相关指标的检测

Zhongguo shiyan zhenduanxue, 2005
目的探讨针对Fas基因的RNA抑制前后缺血再灌注损伤神经细胞凋亡相关指标的变化。方法NGF诱导PC12细胞为类神经细胞。细胞随机分为对照组、模型组、GFP siRNA组;Fas siRNA组。对照组用完全培养液培养,其他三组细胞制作体外缺血再灌注模型。于制作模型前24小时进行转染。于造模后6h进行Fas、Caspase-3表达检测。24 h进行细胞凋亡相关检测。结果1.凋亡率:模型组细胞（39.13±10.63）明显高于对照组（2.85±0.43）,差异有显著性 ...
宋冬晶, 李颖, 邬英全
doaj  

[Resveratrol protects barrier function of mouse brain microvascular endothelial cell monolayers with oxygen/glucose deprivation and PM_2.5 exposure by maintaining mitochondrial dynamics balance]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Qin M, Sun S, Liu J, Gao Y, Wang H, Wang Y, Sun A, Yan J, Wang J, Yu Y.   +9 more
europepmc   +1 more source

MiRNA调控脑缺血/再灌注诱导的自噬信号通路研究进展

Zhongshan Daxue xuebao. Yixue kexue ban
脑卒中时缺血缺氧致脑组织功能损伤，且缺血后脑组织再恢复血液供应时，大量自由基、钙超载等引起脑缺血/再灌注损伤，进一步加重病情。自噬是一种维持细胞内环境稳态的自我保护机制，但过度自噬引起脑组织损伤。MiRNA为小的内源性非编码RNA分子，通过与其靶基因mRNA的3’ -UTR中的互补序列结合，导致翻译抑制或mRNA降解，从基因水平上调控多种生理活动。MiRNA不仅直接作用于自噬相关蛋白，还可通过多种信号通路，参与缺血/再灌注诱导的自噬调控。但关于miRNA调控脑缺血 ...
刘筱蔼, 罗友根
doaj  

[Electroacupuncture improves learning and memory function and promotes hippocampal synaptic regeneration in rats with cerebral ischemia-reperfusion injury]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Lin R, Xia J, Ma X, Li Z.
europepmc   +1 more source

[Asiaticoside alleviates myocardial ischemia-reperfusion injury in rats by inhibiting NLRP3 inflammasome-mediated pyroptosis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Bian F, Ni S, Zhao P, Qi M, Tang B, Wang H, Kang P, Liu J.   +7 more
europepmc   +1 more source

[<i>In vitro</i> cultured calculus bovis alleviates cerebral ischemia/reperfusion injury through regulating microglial polarization and inhibiting NLRP3]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Chu T, Zhang W, Chen J, Pan Z, Wang L, Zhong X, Qiu F, Huang Z.   +7 more
europepmc   +1 more source

Pharmacological inhibition of ENaC or NCX can attenuate hepatic ischemia-reperfusion injury exacerbated by hypernatremia. [PDF]

J Zhejiang Univ Sci B
Chen Y, Li H, Wen P, Zhang J, Wang Z, Cao S, Guo W.   +6 more
europepmc   +1 more source

[Electroacupuncture pretreatment alleviates cerebral ischemia-reperfusion injury in rats by inhibiting ferroptosis through the gut-brain axis and the Nrf2/HO-1 signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhang A, Sun X, Pang B, Wu Y, Shi J, Zhang N, Ye T.   +6 more
europepmc   +1 more source

LncRNA AK154753 mediates the development of acute kidney ischemia reperfusion injury via the miR<b>-</b>345<b>-</b>3p/Bak and miR<b>-</b>708<b>-</b>5p/Bim pathways. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Wen Y, He Y, Deng Y, Zhuang K, Xi J, Li S, Tang C, Chen J.   +7 more
europepmc   +1 more source

[Protective effect of ulinastatin combined with dexmedetomidine against hepatic ischemia-reperfusion injury in laparoscopic hepatectomy for liver cancer and cirrhosis: a randomized controlled trial]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2022
Ou Y, Liu G, Yin F, Yang Y, Zhang F.
europepmc   +1 more source