GSK3β抑制在异氟醚后处理减轻SH-SY5Y细胞缺血再灌注损伤中的作用
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 摘 要: 【目的】 研究糖原合成酶激酶3β(GSK3β)抑制在异氟醚后处理减轻SH-SY5Y细胞缺血再灌注损伤的神经保护中所起的作用?【方法】 将SH-SY5Y细胞进行分成3组(n = 24):Control组?OGD组及OGD + Isoflurane组?Control组细胞常规培养;OGD组进行1 h氧糖剥夺(OGD)及20 h模拟再灌注;OGD + Isoflurane组进行1 h的OGD及20 h模拟再灌注,OGD开始时立即暴露于2%异氟醚1 h?检测各组模拟再灌注1 ...
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[Colchicine alleviates myocardial ischemia-reperfusion injury in mice by activating AMPK]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoChen G, Luo S.
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[Eye acupuncture improves neural function in rats with cerebral ischemia-reperfusion injury by promoting angiogenesis via upregulating METTL3-mediated m6A methylation]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoPu Y, Wang Z, Chu H.
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Buyang Huanwu decoction promotes angiogenesis of rat brain microvascular endothelial cells after oxygen-glucose deprivation reperfusion injury via activation of PI3K-AKT signaling pathway. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue Ban, 2022 Hu X +6 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 评估ＵＷ液动脉预灌洗对缺血肢体Ｉ／Ｒ损伤程度的影响，寻找减轻缺血组织Ｉ／Ｒ损伤的有效方式。【方法】 建立大鼠后肢缺血模型，预灌洗组于肢体恢复血供前，应用ＵＷ液预灌洗３０ｍｉｎ，然后恢复血供；缺血再灌注组不进行预灌洗直接恢复肢体血供，每组８只。通过监测骨骼肌再灌注血流量变化，测定血清ＣＰＫ、ＬＤＨ含量及骨骼肌水含量、ＭＤＡ含量、ＳＯＤ活性、骨骼肌细胞凋亡情况以及骨骼肌的超微结构改变，来评估骨骼肌的Ｉ／Ｒ损伤程度。【结果】 恢复血供后，Ｉ／Ｒ组中骨骼肌血流过度灌注明显，峰值为健侧（２１６ ± ２２）
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Mechanism by which hyperglycemia regulates precursor of brain<b>-</b>derived neurotrophic factor expression to exacerbate neurological injury and inflammation in a mouse model of spinal cord ischemia<b>-</b>reperfusion injury. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanLuo W +5 more
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[Melatonin alleviates myocardial ischemia-reperfusion injury in mice by inhibiting inflammatory response via activating Nrf2 signaling]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2021 Kong L +5 more
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[PI3K/Akt/Erk signaling pathway mediates neuroprotection of CaMKⅡγ and CaMKⅡδ against ischemic reperfusion injury in mice]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLiu H, Lin Z, Ye J.
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[Xenon post-conditioning protects against spinal cord ischemia-reperfusion injury in rats by downregulating mTOR pathway and inhibiting endoplasmic reticulum stress-induced neuronal apoptosis]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2022 Luo L, Tong J, Li L, Jin M.
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[High STING expression exacerbates renal ischemia-reperfusion injury in mice by regulating the TLR4/NF-κB/NLRP3 pathway and promoting inflammation and apoptosis]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoTao H +7 more
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