Results 41 to 50 of about 26,143 (169)

Effect of multi-devascularization combined with Curcumin perfusion in the treatment of hepatic VX2 carcinoma in rabbit and on the residual carcinoma angiogenesis [PDF]

open access: yes, 2015
目的:研究姜黄素和肝脏周围防粘连隔离膜包裹对经肝动脉、门静脉栓塞治疗VX2肝癌兔的肝功能和生存期的影响;碘化油栓塞肿瘤血管后的残癌组织内血管新生旺盛,本实验探讨姜黄素和肝周防粘连隔离膜包裹对栓塞后残癌组织血管新生的影响。 方法:40只新西兰大白兔随机分成4组,开腹接种法建立VX2肝癌模型。两周后开腹行肝动脉、门静脉置管术,其中B组、D组手术置管同时行肝周防粘连隔离膜包裹隔离术。手术一周后通过留置化疗泵给药,A组、B组:单纯碘化油栓塞剂,C组、D组:姜黄素和栓塞剂混合乳剂。即A组:肝动脉、门静脉置管 ...
徐政
core  

Injectable Biomimetic Composite Hydrogel Scaffold With Tissue‐Engineered Cartilage Matrix for Articular Cartilage Regeneration

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu   +13 more
wiley   +1 more source

Endogenous/Exogenous Dual‐Responsive Bimetallic Hollow Nanozyme for Photothermal/Nanocatalysis/Immune Synergistic Tumor Therapy

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley   +1 more source

热疗联合ADM诱导肝癌细胞BEL-7402/ADM凋亡的实验研究

open access: yesZhongguo shiyan zhenduanxue, 2005
目的 研究热化疗诱导多药耐药肝癌细胞BEL 74 0 2 /ADM凋亡的效果 ,为热化疗在治疗已产生多药耐药性的原发性肝癌方面的应用提供理论依据。方法 将BEL 74 0 2 /ADM分为对照组、单纯热疗组、热化疗 3组 ,应用热疗联合阿霉素诱导BEL 74 0 2 /ADM细胞凋亡 ,以流式细胞仪、TUNEL染色法检测其凋亡率。结果 对照组、单纯化疗组细胞凋亡率分别为 3 2 4± 1 5 6 %、4 12± 1 77% ;而BEL 74 0 2 /DM +ADM +热疗 (热化疗组 )凋亡率为 ...
王宁, 杨海山, 刘洁, 李玉
doaj  

A Prospective Randomized Study of the Radiotherapy Volume for Limited-stage Small Cell Lung Cancer: A Preliminary Report [PDF]

open access: yes, 2010
Background and objective Controversies exists with regard to target volumes as far as thoracic radiotherapy (TRT) is concerned in the multimodality treatment for limited-stage small cell lung cancer (LSCLC).
Fenghua WANG   +16 more
core  

Boron Difluoride Chelated Aminoanthraquinone Photosensitizer for Type I Photodynamic Therapy

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Type I photosensitizers capable of generating cytotoxic reactive oxygen species (ROS), with reduced oxygen dependence under photoirradiation, are regarded as a promising phototherapeutic approach for hypoxic solid tumors. Herein, based on the electron donor of 9‐phenyl‐carbazole (Cz) and the electron acceptor of anthraquinone (AQ ...
Tian Zhang   +8 more
wiley   +1 more source

A Prospective Randomized Study of Adjuvant Chemotherapy in Resected Stage IIIA-N2 Non-small Cell Lung Cancer [PDF]

open access: yes, 2009
Background and objective Lung cancer is one of the leading cause of cancer-related death around the world. Surgery is the primary treatment for patients with stage I, II, or IIIA non-small cell lung cancer (NSCLC).
Binbin ZHANG   +6 more
core  

Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu   +12 more
wiley   +1 more source

乳腺癌根治术后辅助治疗的作用

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1988
本文将我院自1964.4~1982.12月收治的女性单侧Ⅱ、Ⅲ期乳腺癌554例,根据不同治疗方法的组合分为四组:根治术组(160例),根治术+化疗组(182例),根治术+放疗组(137例),根治术+化疗+放疗组(75例),并分析比较了各组的疗效,局部复发率及远处转移率,以探讨各种辅助治疗在Ⅱ、Ⅲ期乳腺癌根治术后的价值。本文资料表明:化学治疗是乳腺癌根治术后一种较好的辅助治疗。术后预防性放射治疗不能提高乳腺癌根治术的疗效,亦不能减少局部复发及远处转移。术后同时并用化疗及放疗 ...
戎铁华
doaj  

化疗药与维拉帕米、利多卡因和法莫替丁联用对肝癌细胞系的影响

open access: yesZhongguo shiyan zhenduanxue, 2012
原发性肝癌是常见恶性肿瘤之一,临床对于多数中晚期恶性肿瘤患者往往缺少有效的治疗手段;介入治疗近年来以其可靠的疗效及较低的并发症逐渐成为中晚期原发性肝癌的首选治疗方法;我科近年来行肝动脉留管持续化疗,取得满意效果;据文献报告,维拉帕米[1]可以逆转癌细胞对多种化疗药的耐药性,利多卡因、H2受体阻断剂[2]与化疗药有协同作用 ...
朱林忠, 朱旭, 杨仁杰, 宁涛
doaj  

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