【目的】 探讨新辅助化疗对Ⅰb2 ~ Ⅲb期宫颈癌的近期临床疗效? 【方法】 选择我院2003年6月~2007年9月收治的经病理确诊的28例Ⅰb2 ~ Ⅲb期宫颈癌患者,动脉介入化疗18例,化疗方案:卡铂(300 mg/m2)+博来霉素(45 mg);静脉化疗10例,化疗方案:卡铂(AUC 6)+5*9鄄FU(4 000 mg/m2 > 96 h)?化疗10 ~ 14 d重新评估,化疗2 ~ 3周行广泛全子宫切除术+盆腔淋巴结清扫术,观察近期临床疗效?【结果】 化疗有效率82.1%(23/28 ...
温国群
doaj
A Prospective Randomized Study of the Radiotherapy Volume for Limited-stage Small Cell Lung Cancer: A Preliminary Report [PDF]
Background and objective Controversies exists with regard to target volumes as far as thoracic radiotherapy (TRT) is concerned in the multimodality treatment for limited-stage small cell lung cancer (LSCLC).
Fenghua WANG +16 more
core
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
Nursing care of a case with hypertension induced by paclitaxel chemotherapy
为探讨紫杉醇化疗毒副反应之一高血压的护理 ,对门诊接受紫杉醇化疗的病人在化疗期间加强心理护理和生命体征监测 ,去除焦虑因素 ,并对化疗过程中发生高血压的病人给予对症处理并严密观察 ,使病人顺利完成了化疗。
高瑞珍 +3 more
doaj
Effect of multi-devascularization combined with Curcumin perfusion in the treatment of hepatic VX2 carcinoma in rabbit and on the residual carcinoma angiogenesis [PDF]
目的:研究姜黄素和肝脏周围防粘连隔离膜包裹对经肝动脉、门静脉栓塞治疗VX2肝癌兔的肝功能和生存期的影响;碘化油栓塞肿瘤血管后的残癌组织内血管新生旺盛,本实验探讨姜黄素和肝周防粘连隔离膜包裹对栓塞后残癌组织血管新生的影响。 方法:40只新西兰大白兔随机分成4组,开腹接种法建立VX2肝癌模型。两周后开腹行肝动脉、门静脉置管术,其中B组、D组手术置管同时行肝周防粘连隔离膜包裹隔离术。手术一周后通过留置化疗泵给药,A组、B组:单纯碘化油栓塞剂,C组、D组:姜黄素和栓塞剂混合乳剂。即A组:肝动脉、门静脉置管 ...
徐政
core
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
ABSTRACT Psychedelic interventions are not publicly available through Canada's healthcare system. Despite growing scientific evidence, public interest, and efforts to expand access to psychedelic therapies for end‐of‐life psychological suffering, Canadian policies remain restrictive.
Sarah Kratina +4 more
wiley +1 more source
The role of hedgehog pathway and autophagy in the mechanism of acquired chemoresistance in multiple myeloma [PDF]
在多发性骨髓瘤的临床治疗中,化疗耐药现象仍然是治疗失败的主要原因之一。为了更好地了解多发性骨髓瘤的化疗耐药性及相关的机制,我们建立了阿霉素(doxorubicin,DOX)耐药的细胞系多发性骨髓瘤细胞系RPMI8226/R(doxorubicin-resistantcellline),DOX对8226/R的半数抑制率(IC50)是对DOX敏感的细胞系RPMI8226/S(chemosensitivecellline)的5~6倍。我们发现在多发性骨髓瘤耐药性的诱导过程中存在Hedgehog(Hh ...
黄潇
core
Negotiating Centralization: How Local Networks Reshaped Scotland's National Care Service Reform
ABSTRACT Centralizing reforms frequently diverge from their original designs, yet the processes through which this divergence occurs remain insufficiently understood. This article examines Scotland's National Care Service reform (2021–2025), a major recentralization that underwent significant modification following sustained engagement from local ...
Awais Mashkoor
wiley +1 more source
热疗联合ADM诱导肝癌细胞BEL-7402/ADM凋亡的实验研究
目的 研究热化疗诱导多药耐药肝癌细胞BEL 74 0 2 /ADM凋亡的效果 ,为热化疗在治疗已产生多药耐药性的原发性肝癌方面的应用提供理论依据。方法 将BEL 74 0 2 /ADM分为对照组、单纯热疗组、热化疗 3组 ,应用热疗联合阿霉素诱导BEL 74 0 2 /ADM细胞凋亡 ,以流式细胞仪、TUNEL染色法检测其凋亡率。结果 对照组、单纯化疗组细胞凋亡率分别为 3 2 4± 1 5 6 %、4 12± 1 77% ;而BEL 74 0 2 /DM +ADM +热疗 (热化疗组 )凋亡率为 ...
王宁, 杨海山, 刘洁, 李玉
doaj

