Results 11 to 20 of about 3,696 (153)
Journal of Diabetes, Volume 15, Issue 11, Page 987-993, November 2023., 2023 Highlights We used data from the genome‐wide association studies database and two‐sample mendelian randomization method, we found that genetic evidence supporting that knee osteoarthritis is a potential risk factor for type 2 diabetes. Abstract Background Physical inactivity is an independent risk factor for type 2 diabetes (T2D).
Xing Xing +3 more
wiley +1 more source
Evaluation and redesign of the primers for detecting nitrogen cycling genes in environments
Methods in Ecology and Evolution, Volume 13, Issue 9, Page 1976-1989, September 2022., 2022 Abstract A better understanding of how nitrogen (N) cycling genes are involved in ecological processes is one of the crucial areas of microbial ecology. Currently, most molecular biological techniques investigating N cycling genes in the environment heavily rely on the accuracy of the polymerase chain reaction (PCR) primers; however, their specificity ...
Zhujun Wang +12 more
wiley +1 more source
Journal of Diabetes, Volume 13, Issue 2, Page 143-153, February 2021., 2021 Highlights A machine learning model can significantly predict imminent development of islet autoimmunity based on environmental, genetic, and metabolic features. The machine learning algorithm feature selection identified type 1 diabetes‐associated single nucleotide polymorphisms from The Environmental Determinants of the Diabetes in the Young (TEDDY ...
Bobbie‐Jo M. Webb‐Robertson +10 more
wiley +1 more source
Journal of Diabetes, Volume 11, Issue 11, Page 857-868, November 2019., 2019 Highlights Ten single nucleotide polymorphisms were found to be associated with diabetes risk. There were significant associations of diabetes genetic risk scores and weighted diabetes genetic risk scores with fasting plasma glucose and diabetes. Abstract Background Genome‐wide association studies have identified loci that significantly increase ...
Chao Song +11 more
wiley +1 more source
Integrative Conservation, Volume 4, Issue 3, Page 405-415, September 2025.Assessing the genetic diversity of edible insects harvested from the wild is a pre‐requisite for designing conservation and management policies. The caterpillars of Gynanisa maja (Saturniidae) are harvested in large numbers in mopane woodlands in southern Africa, where they represent a seasonal source of income and nutrition to many rural communities ...
Zwannda Nethavhani +3 more
wiley +1 more source
Integrative Conservation, Volume 4, Issue 3, Page 277-286, September 2025.This study provides an innovation to address the challenge in accessibility to samples and genetic markers in Snow leopard conservation genetic studies. We performed next‐generation sequencing (NGS) on 19 fecal samples obtained from the eastern Qinghai‐Tibet Plateau, and successfully assembled 17 complete mitogenome sequences (~16,720 bp) and ...
Chen Cheng +7 more
wiley +1 more source
The association study between the polymorphisms in P53 and MDM2 and the genetic susceptibility of primary hepatocellular carcinoma among Xiamen population [PDF]
, 2015 目的 探讨厦门市P53基因rs1042522位点、MDM2基因rs2279744位点的单核苷酸多态性（SNP）与原发性肝细胞癌（HCC）遗传易感性的关系，为筛检肝癌高危人群，以及进行肝癌一、二级预防提供参考依据。 方法 采用病例-对照研究设计，抽样调查在2011年1月至2014年10月间厦门市综合性三甲医院就诊的肝癌患者和健康对照者。病例组纳入标准：根据HCC诊断依据在调查期间被首次确诊为HCC、年龄≥18岁、现住址与调查地属同一区（县）级范围、无任何其他肿瘤史的患者。排除标准：患有HCC以外的肿瘤 ...
潘欢欢
core
Molecular cloning, expression of heat shock protein 60 (HSP60) gene in Marsupenaeus japonicus and the association of its polymorphisms with thermal tolerance [PDF]
, 2015 日本囊对虾(Marsupenaeusjaponicus)是我国重要经济养殖虾类，但其在南方地区存在着高温度夏死亡率较高的养殖难题。因此，急需了解日本囊对虾的耐热性状及耐温的分子机制，为此，我们开展了日本囊对虾MjHSP60基因的克隆、表达分析及其多态性与耐热性状相关性的研究，获得了如下主要结果： 1.MjHSP60基因克隆 在日本囊对虾MjHSP60cDNA序列基础上克隆到了该基因DNA全序列。日本囊对虾MjHSP60基因全长4055bp，结构与拟穴青蟹一致，均由8个外显子及7个内含子构成 ...
李丽君
core
Screening of SNP Loci of Growth-related Candidate Gene and Genetic Diversity of Five Populations Based On Microsatellite Markers in Fujian Oyster, Crassostrea angulata [PDF]
, 2015 福建牡蛎(Crassostreaangulata，C.angulata)又名葡萄牙牡蛎，具有重要的经济价值和生态价值，但由于长期未经选育以及人工育苗的应用，导致牡蛎养殖出现经济性状衰退及死亡率逐年增高等现象，亟需加强种质资源保护，开展遗传改良研究。本研究利用单核苷酸多态性分子标记（singlenucleotidepolymorphism，SNP）对福建牡蛎生长相关的5个候选基因，即胰岛素相关多肽（insulinrelatedpeptides，IRPs）、ɑ-淀粉酶（ɑ-Amylase，ɑ-AMY ...
楚瑞敏
core
Zhongguo shiyan zhenduanxue, 2012 目的采用高分辨熔解曲线（high-resolution melting,HRM）方法检测7个2型糖尿病（T2DM）患者相关易感单核苷酸多态性,并分析该多态性与2型糖尿病的相关性。方法选取202名T2DM患者和200名健康志愿者,提取外周血DNA,采用HRM技术分析其多态性,并用测序法证实。结果成功地检测T2DM患者相关易感单核苷酸多态性。HRM技术检测能准确区分各种基因型,其结果与测序法一致;研究还显示rs10811661和rs10923931位点在本研究人群中与T2DM无相关 ...
左玲, 左磊
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