Results 71 to 80 of about 1,168,224 (184)
Zhongguo shiyan zhenduanxue, 2013 目的探讨拉米夫定耐药感染者HBV基因型与YMDD变异的相关性。方法采用PCR扩增后测序的方法,对162例拉米夫定耐药感染者进HBV基因型的分析。实时荧光定量PCR法检测HBV YMDD变异及HBV DNA载量。率的比较采用χ2检验法,两组均数间的比较采用t检验法。结果 162例拉米夫定耐药感染者中,B基因型102例（63.0%）,C基因型60例（37.0%）。YMDD变异111例（68.5%）,其中YIDD变异30例（18.5%）,YVDD变异32例（19.7%）,YIDD/YVDD混合型变异49例 ...
张志珊 +6 more
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[Phenotype and genotype characteristics of children with cardiomyopathy associated with MYH7 gene mutation: a retrospective analysis]. [PDF]
Zhongguo Dang Dai Er Ke Za Zhi, 2023 Liu L, Zheng K, Zhang YQ.
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Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Photocatalysis has emerged as a promising approach for solar energy conversion and environmental remediation. However, its practical implementation is still hindered by limited charge‐separation efficiency, slow surface reaction kinetics, and insufficient catalyst stability.
Mengting Zhang +5 more
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, 2012 针对全氟化合物这类新型的有机污染物,在环境中具有持久性,生物累积性和毒性的问题,以全氟辛酸为模型化合物,以真核生物酵母以及4基因缺失型酵母突变体和5基因缺失型酵母突变体为模式生物,开发便捷、灵敏的毒理学评价方法,探究全氟辛酸对不同基因缺失型酵母的毒性效应,以期建立以酵母为平台的环境污染物快速筛选系统.研究结果表明,5基因缺失型酵母突变体对全氟辛酸较为敏感 ...
程巧红, 戴和平, 金士威
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Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Magnesium hydride (MgH2) is a promising solid‐state hydrogen storage material due to its high gravimetric capacity and excellent reversibility. However, its practical application is hindered by high thermodynamic stability and sluggish reaction kinetics.
Xingyang Chen +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2019 目的建立成骨细胞条件性FKBP8基因敲除小鼠模型、为研究FKBP8基因在骨质疏松症中的作用机制提供动物模型。方法设计基因敲除策略,获得纯合子小鼠和野生型对照小鼠。提取鼠尾DNA,PCR扩增之后琼脂糖凝胶电泳鉴定小鼠基因型。提取小鼠原代成骨细胞蛋白质,利用Western blot技术检验FKBP8基因的表达。结果成功构建成骨细胞条件性FKBP8小鼠敲除模型,PCR结果显示基因型为BGLAP-Cre/FKBP8flox/flox,Western blot结果显示FKBP8基因蛋白表达敲除效果明显 ...
王红 +4 more
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Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Developing electrode materials with high capacity and outstanding activity is essential for energy storage and conversion technologies. However, integrating multiple functions into a single material remains challenging. Herein, we synthesized a novel CoP@NiCo layered double hydroxide (CoP@NiCo‐LDH) nano‐electrode using hydrothermal and ...
Ruiyu Li +9 more
wiley +1 more source
人工鲤鲫多倍体谱系各生物型的基因组组成、基因表达及生殖模式研究
, 2001 本论文分为三章，第一章为文献综述，第二章为人工鲤鲫多倍体谱系各种生物型的基因组组成、基因表达特点及鲤鲫杂种二倍体和四倍体的生殖模式研究，第三章为鲤鲫杂种四倍体天然雌核发育的分子证据。第一章：概述了鱼类天然雌和发育的遗传、演化、和起源等方面的研究现状及进展，以及DNA标记技术和蛋白及同工酶标记在鱼类遗传育种等领域的应用，并指出了鲤鲫人工多倍体谱系在鱼类雌核发育研究中的意义及价值。第二章：采用聚丙烯酰胺梯度电泳技术对人工鲤鲫多倍体谱系不同生物型的同工酶及蛋白基因的表达进行了系统的研究 ...
王小虎
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HBV-DNA高水平孕妇的HBV 前S和S区基因突变及基因分型
Zhongshan Daxue xuebao. Yixue kexue ban, 2012 【目的】 研究HBV-DNA高水平孕妇的HBV前S(前S1和前S2)及S区的基因突变模式和基因分型,为从病毒因素探讨HBV母婴传播免疫阻断失败提供实验基础【方法】 选取血清HBsAg阳性且HBV-DNA≥105 IU/ mL的孕妇41 例,提取血清HBV-DNA,靶向设计HBV各基因型的前S及S区通用引物, 经PCR 扩增测序进行序列分析, 检测和分析前S及S区基因的突变情况,并进行基因分型【结果】 ①在 41 例样本中, 共有29例( 70.73%)样本存在前S1前S2及S区基因突变 ...
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