Results 11 to 20 of about 20,056 (169)
肾素-血管紧张素系统基因多态性与慢性心力衰竭的关系 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 [目的]探讨中国南方汉族人群中,血管紧张素转换酶（ACE）及血管紧张素原（AGT）双基因多态性与慢性心力衰竭发病的关系.[方法]用聚合酶链反应及限制性片段长度多态性技术检测111例慢性心力衰竭患者和110例健康者的ACE基因I/D及AGT基因M235T的多态性.[结果]①慢性心力衰竭组DD基因型与D等位基因的频率均高于对照组.DD基因型0.468比0.227,P＜0.01;D等位基因0.667比0.436,P＜0.01.②AGT基因M235T多态性在慢性心力衰竭组及对照组的分布无统计学差异 ...
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血液透析者低密度脂蛋白受体基因多态性及其对血脂的影响 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2004 【目的】探讨血液透析患者低密度脂蛋白受体(LDLR)基因多态性及其对脂代谢的影响。【方法】生化方法检测112例血液透析血清脂质水平,多聚酶链反应-限制性片段长度法检测105例血液透析患者LDLR内含子4TaqⅠ位点与80例血液透析患者外显子13AvaⅡ位点基因多态性。【结果】血液透析患者脂代谢紊乱主要表现为血清甘油三酯、载脂蛋白B水平显著增高。血液透析组与对照组LDLR内含子4TaqⅠ位点与外显子13AvaII位点基因型及等位基因分布频率无显著差异(P>0.05 ...
王玉新
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Association of MTHFR C677T polymorphism with male infertile in Xiamen area [PDF]
, 2017 目的探讨亚甲基四氢叶酸还原酶（MTHFR）C677T基因多态性与男性不育的相关性。方法选取少、弱精症患者66例和无精症患者74例为实验组,精液正常且有正常孕育史的男性96例为对照组,分析MTHFR C677T基因多态性在三组中分布的差异。结果与对照组相比,少、弱精组中MTHFR C677T各基因型的频率差异没有显著性意义（P〉0.05）;与对照组相比,无精组中MTHFR C677T各基因型的频率差异没有显著性意义（P〉0.05）。结论在少、弱精症患者、无精症患者和健康人中,基因多态性分布无显著差异 ...
王厚照, 谭振军, 马芳芳
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Research Progress on the Relationship between Genetic Polymorphism and Violent Behavior of Patients with Schizophrenia [PDF]
, 2020 Schizophrenia is a common disease characterized by thinking obstructions and accompanied by cognitive, emotional and behavioral disorders. Under the control of psychiatric symptoms, patients with schizophrenia may self-injure or impulsively wound others,
XU Shuo, LIANG Yi-ying, HONG Bin-xue,et al
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Correlation between the Polymorphism of Coagulation-Related Genes and Lower Extremity Deep Venous Thrombosis [PDF]
, 2021 Objective To investigate the correlation between the polymorphism of 4 coagulation-related genes, rs1799963 （coagulation factor V gene Leiden）, rs6025 （prothrombin gene G20210A）, rs1042579 （thrombomodulin protein gene c.1418C>T） and rs1801131 ...
JIANG Yao-ru, NIU Lei-lei, FENG Na, et al.
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The effect of PNPLA3 ploymorphism in the intervention of non-alcoholic fatty liver disease [PDF]
, 2015 研究目的 运动是治疗非酒精性脂肪性肝疾病的一个重要方法，而脂肪滋养蛋白基因（PNPLA3）是非酒精性脂肪性肝疾病的一个重要的基因遗传因子。本研究的目的是为了探讨脂肪滋养蛋白基因的多态性表达是否影响到运动干预非酒精性脂肪性肝疾病的过程。 研究方法 本研究共招募40-65岁中心性肥胖受试者1059人，进行常规体检，并运用彩超检测脂肪肝。并随机抽取476名肥胖受试者进行1H-MRS对其肝内甘油三酯进行定量测定。在这476名肥胖受试者中，随机抽取220人分为三组，强化运动组（先进行6个月的强化运动期 ...
黄竹锋
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Integrative Conservation, EarlyView.Pometia pinnata demonstrated life‐stage‐specific genetic responses to landscape features, with asymmetric gene flow patterns and population recovery following historical bottlenecks, revealing complex topographic and demographic influences on forest genetic structure.
Madhuparna Chatterjee +5 more
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Association between Polymorphisms of ERCC1 and Response in Patients with Advanced Non-small Cell Lung Cancer Receiving Cisplatin-based Chemotherapy [PDF]
, 2010 Background and objective Results of studies on genetic polymorphisms of ERCC1 gene in DNA repair pathway which may affect response to platinum-based chemotherapy and survival in patients with non-small cell lung cancer are conflicting.
Hui ZHANG +6 more
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Integrative Conservation, EarlyView.We collated detections of the sun bear from new and previously published camera trap studies across its range. We then analysed these detections at two different spatial scales to assess the habitat associations and diel activity of this species. We found that the sun bear is tolerant to moderate habitat disturbances. ABSTRACT Degraded tropical forests,
Alexander Hendry +5 more
wiley +1 more source
Investigation of the association between adult intelligence and Apolipoprotein E genotype in the young Chinese Han population [PDF]
, 2015 载脂蛋白E（ApolipoproteinE）在脂质代谢及分布中具有重要作用。载脂蛋白E基因具有多态性，包含了APOEɛ2、APOEɛ3和APOEɛ4三种。其中，ɛ4等位基因是引起迟发型阿尔茨海默病（Late-onsetAlzheimer’sDisease）最重要的危险因素。尽管许多研究表明在老年人中APOE基因的多态性与认知功能密切相关，但其对青年人认知功能的影响研究非常少，并且有限的研究结果存在争议性。为了进一步探讨APOE基因多态性对青年人认知功能的影响 ...
魏孜辰
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