Results 11 to 20 of about 25,254 (214)

血管紧张素转换酶、内皮型一氧化氮合酶和载脂蛋白E基因多态性与冠心病的相关性 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2006
[目的]研究血管紧张素转换酶(ACE)基因插入/缺失多态性、内皮型一氧化氮合酶(eNOS)基因G894T多态性和载脂蛋白E(ApoE)基因多态性与冠状动脉粥样硬化性心脏病(冠心病)的关系.[方法]应用基因芯片技术分析133例冠心病患者和122例对照者ACE、eNOS和ApoE基因多态性,对比两组基因型及等位基因频率.[结果]冠心病组ACE DD基因型频率比对照组显著升高,28.6% vs 13.1%,P<0.01,ACE基因多态性与冠心病危险性相关.两组eNOS和ApoE基因型频率差异无统计学意义(P ...
梁茜   +4 more
doaj   +2 more sources

肾素-血管紧张素系统基因多态性与慢性心力衰竭的关系 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2006
[目的]探讨中国南方汉族人群中,血管紧张素转换酶(ACE)及血管紧张素原(AGT)双基因多态性与慢性心力衰竭发病的关系.[方法]用聚合酶链反应及限制性片段长度多态性技术检测111例慢性心力衰竭患者和110例健康者的ACE基因I/D及AGT基因M235T的多态性.[结果]①慢性心力衰竭组DD基因型与D等位基因的频率均高于对照组.DD基因型0.468比0.227,P<0.01;D等位基因0.667比0.436,P<0.01.②AGT基因M235T多态性在慢性心力衰竭组及对照组的分布无统计学差异 ...
doaj   +2 more sources

Association of adipocytokine pathway gene polymorphisms with NAFLD in obese children. [PDF]

open access: greenZhong Nan Da Xue Xue Bao Yi Xue Ban
Wang J   +8 more
europepmc   +3 more sources

Association of MTHFR C677T polymorphism with male infertile in Xiamen area [PDF]

open access: yes, 2017
目的探讨亚甲基四氢叶酸还原酶(MTHFR)C677T基因多态性与男性不育的相关性。方法选取少、弱精症患者66例和无精症患者74例为实验组,精液正常且有正常孕育史的男性96例为对照组,分析MTHFR C677T基因多态性在三组中分布的差异。结果与对照组相比,少、弱精组中MTHFR C677T各基因型的频率差异没有显著性意义(P〉0.05);与对照组相比,无精组中MTHFR C677T各基因型的频率差异没有显著性意义(P〉0.05)。结论在少、弱精症患者、无精症患者和健康人中,基因多态性分布无显著差异 ...
王厚照, 谭振军, 马芳芳
core   +1 more source

Correlation between the Polymorphism of Coagulation-Related Genes and Lower Extremity Deep Venous Thrombosis [PDF]

open access: yes, 2021
Objective To investigate the correlation between the polymorphism of 4 coagulation-related genes, rs1799963 (coagulation factor V gene Leiden), rs6025 (prothrombin gene G20210A), rs1042579 (thrombomodulin protein gene c.1418C>T) and rs1801131 ...
JIANG Yao-ru, NIU Lei-lei, FENG Na, et al.
core   +1 more source

Research Progress on the Relationship between Genetic Polymorphism and Violent Behavior of Patients with Schizophrenia [PDF]

open access: yes, 2020
Schizophrenia is a common disease characterized by thinking obstructions and accompanied by cognitive, emotional and behavioral disorders. Under the control of psychiatric symptoms, patients with schizophrenia may self-injure or impulsively wound others,
XU Shuo, LIANG Yi-ying, HONG Bin-xue,et al
core   +1 more source

The effect of PNPLA3 ploymorphism in the intervention of non-alcoholic fatty liver disease [PDF]

open access: yes, 2015
研究目的 运动是治疗非酒精性脂肪性肝疾病的一个重要方法,而脂肪滋养蛋白基因(PNPLA3)是非酒精性脂肪性肝疾病的一个重要的基因遗传因子。本研究的目的是为了探讨脂肪滋养蛋白基因的多态性表达是否影响到运动干预非酒精性脂肪性肝疾病的过程。 研究方法 本研究共招募40-65岁中心性肥胖受试者1059人,进行常规体检,并运用彩超检测脂肪肝。并随机抽取476名肥胖受试者进行1H-MRS对其肝内甘油三酯进行定量测定。在这476名肥胖受试者中,随机抽取220人分为三组,强化运动组(先进行6个月的强化运动期 ...
黄竹锋
core  

Flexible parental care in a songbird correlates with sex‐specific responses to seasonal phenology, mating opportunity and reproductive success

open access: yesJournal of Animal Ecology, EarlyView.
This population‐comparative study reveals that male and female parents respond differently to social and ecological conditions. This sex‐specific responsive strategy is related to the incongruent parental care systems across populations in Chinese penduline tits.
Jia Zheng   +5 more
wiley   +1 more source

Association between Polymorphisms of ERCC1 and Response in Patients with Advanced Non-small Cell Lung Cancer Receiving Cisplatin-based Chemotherapy [PDF]

open access: yes, 2010
Background and objective Results of studies on genetic polymorphisms of ERCC1 gene in DNA repair pathway which may affect response to platinum-based chemotherapy and survival in patients with non-small cell lung cancer are conflicting.
Hui ZHANG   +6 more
core  

Rapid construction of insect–plant interaction networks via multiplexed long‐fragment DNA metabarcoding and NGS

open access: yesMethods in Ecology and Evolution, EarlyView.
Abstract Molecular identification of insect food webs can accurately reveal complex trophic interactions and serve as a foundation for understanding ecosystem functioning and advancing biodiversity conservation. This process typically involves DNA library construction, high‐throughput sequencing and subsequent steps, including data assembly, annotation,
Xiao‐man Zhang   +9 more
wiley   +1 more source

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