Results 21 to 30 of about 22,208 (188)
Rare Metals, EarlyView.ABSTRACT High‐power piezoelectric ceramics which have a wide operating temperature range are essential for sensor and actuator applications in extreme conditions. However, their development is fundamentally hindered by the inherent trade‐off among key parameters (TC, d33, Qm).
Rui Yan +10 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2003 目的 探讨儿童持续性蛋白尿与血管紧张素转换酶基因多态性的关系。方法 用PCR方法检测了 186例儿童持续性蛋白尿患儿ACE基因多态性及ACE基因多态性与尿蛋白量、血尿、高血压、氮脂血症的关系。结果 持续性蛋白尿患儿ACE -DD基因频率为 0 .2 0 ,II基因频率为 0 .5 2 ,DI基因频率为 0 .2 8;持续性蛋白尿患儿ACE基因多态性与正常对照组存在明显差异 ;尿蛋白量与ACE基因多态性有关 ,大量蛋白尿多为ACE -II型 ;在紫癜性肾炎组血尿的发生以II型为主 ...
李丽红 +5 more
doaj
Study on Multicolor Melting Curve Analysis-based Approaches for the Detection of Gene Polymorphisms Related to Pharmacogenomics [PDF]
, 2017 个体间药物响应的差异性长期困扰着临床，不同病人对同样剂量的同种药物所表现出的疗效和毒副作用往往不同。药物基因组学研究表明，基因多态性对个体药物响应差异起主导作用。伴随药物基因组学的深入研究，药物基因组生物标记物也不断被发现。基因检测是实现个体化用药的重要手段，通过检测相关基因多态性，可指导临床个体化用药，从而提高药物疗效和降低药物不良反应。本文将多色探针熔解曲线分析技术用于药物代谢酶基因CYP2D6、DPYD，药物转运体基因SLCO1B1，药物作用靶点基因ADRB1、APOE、ANKK1 ...
赖小芳
core
Wildlife Letters, EarlyView.This review summarizes the status of musk deer in China, highlighting severe population declines due to illegal hunting and habitat loss, and proposes integrated conservation strategies including habitat protection, captive breeding, and law enforcement to support the recovery and sustainable management of this ecologically and economically important ...
Feng Jiang +8 more
wiley +1 more source
E-选择素基因rs3917422A和rs5355C位点多态性与哈尼族原发性高血压相关性研究
Zhongguo shiyan zhenduanxue, 2009 目的探讨E-选择素基因rs3917422A\C和rs5355C\T位点多态性与哈尼族原发性高血压的关系。方法采用PCR测序技术,对云南哈尼族172例原发性高血压患者和133例正常对照的E-选择素基因rs3917422A\C和rs5355C\T的错义突变进行检测。结果在哈尼族中未发现有rs3917422A多态存在,发现rs5355C基因有多态存在。rs5355C等位基因频率在原发性高血压组中为10.5%,正常对照组中为13.2%,两组之间无显著性差异（P=0.311,P>0.05）。结论哈尼族中E ...
黎曼侬 +6 more
doaj
拟行PCI术冠心病患者CYP2C19、ApoE基因多态性分布研究
Zhongguo shiyan zhenduanxue, 2021 目的研究拟行PCI术(percutaneous transluminal coronary intervention,经皮冠状动脉介入治疗)冠心病患者的CYP2C19、ApoE基因多态性的分布特点,并探讨基因多态性与血小板聚集率水平、血脂水平的关系。方法收集2019年1月至2019年5月于川北医学院附属医院心内科就诊的拟行PCI术的初诊冠心病患者,用PCR-微阵列芯片法检测CYP2C19基因多态性、实时荧光PCR法检测ApoE基因多态性、血小板聚集实验(比浊法)(ADP诱导)检测血小板聚集率 ...
喻晓倩 +5 more
doaj
Relationship between NF-κB gene Polymorphisms and Inflammation injure of Hepatitis B [PDF]
, 2017 [目的] 探讨NF-κB基因多态性在乙型病毒性肝炎炎症损伤进展中的影响，为今后有效控制肝脏慢性炎性损伤提供理论依据。 [方法] 于2015年9月-2016年9月收集厦门市中医院肝病科乙肝病毒高载量慢性乙肝住院病例，对所有病例进行问卷调查，了解性别、年龄、HBV感染初次发现年龄、肝脏疾病家族史、吸烟饮酒史等基础资料及乙肝病毒载量、肝脏炎症等级等临床资料，其中慢性乙肝轻型肝炎患者作为对照组，中型及重型肝炎患者作为病例组；采集入组对象空腹外周血5ml，进行病毒载量确认及提取患者DNA样本 ...
王传鹏
core
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Forests worldwide are increasingly impacted by drought due to climate change, prompting plants to adapt through dehydration tolerance (DT) and avoidance (DA), two distinct physiological strategies.
Xingyun Liang +11 more
wiley +1 more source
血液透析者低密度脂蛋白受体基因多态性及其对血脂的影响 [PDF]
, 2004 【目的】探讨血液透析患者低密度脂蛋白受体(LDLR)基因多态性及其对脂代谢的影响。【方法】生化方法检测112例血液透析血清脂质水平,多聚酶链反应-限制性片段长度法检测105例血液透析患者LDLR内含子4TaqⅠ位点与80例血液透析患者外显子13AvaⅡ位点基因多态性。【结果】血液透析患者脂代谢紊乱主要表现为血清甘油三酯、载脂蛋白B水平显著增高。血液透析组与对照组LDLR内含子4TaqⅠ位点与外显子13AvaII位点基因型及等位基因分布频率无显著差异(P>0.05 ...
王玉新
core
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract The nested subset pattern (nestedness) has been widely used to explain species distributions in island and fragmented systems. Mountain sky islands serve as critical natural laboratories for understanding the evolutionary consequences of geographic isolation and climate
Caiwen Zhang +5 more
wiley +1 more source