Results 21 to 30 of about 25,949 (219)
Association of matrix metalloproteinase-9 C1562T polymorphism and coronary artery disease: a meta-analysis [PDF]
, 2014 Objective: Many investigations have studied the associations between matrix metalloproteinase-9 (MMP-9) C1562T polymorphisms and coronary artery disease (CAD). However, the conclusions of these studies were inconsistent.
Lei-zhi Shi, Xiao Wang
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People and Nature, EarlyView.Abstract Water‐related ecosystem services (WES) provided by urban rivers are influenced by complex interactions between social and ecological systems. Understanding the public perception of WES is crucial for sustainable planning and management of urban rivers in the future. Although studies on public perception on WES have been growing in recent years,
Qianzi Jiang +6 more
wiley +1 more source
Study on Multicolor Melting Curve Analysis-based Approaches for the Detection of Gene Polymorphisms Related to Pharmacogenomics [PDF]
, 2017 个体间药物响应的差异性长期困扰着临床，不同病人对同样剂量的同种药物所表现出的疗效和毒副作用往往不同。药物基因组学研究表明，基因多态性对个体药物响应差异起主导作用。伴随药物基因组学的深入研究，药物基因组生物标记物也不断被发现。基因检测是实现个体化用药的重要手段，通过检测相关基因多态性，可指导临床个体化用药，从而提高药物疗效和降低药物不良反应。本文将多色探针熔解曲线分析技术用于药物代谢酶基因CYP2D6、DPYD，药物转运体基因SLCO1B1，药物作用靶点基因ADRB1、APOE、ANKK1 ...
赖小芳
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Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Grazing by large herbivores is a critical factor shaping grassland biodiversity and ecosystem functioning worldwide, yet its consequences for soil communities remain poorly understood.
Quanhui Ma +12 more
wiley +1 more source
The association study between the polymorphisms in P53 and MDM2 and the genetic susceptibility of primary hepatocellular carcinoma among Xiamen population [PDF]
, 2015 目的 探讨厦门市P53基因rs1042522位点、MDM2基因rs2279744位点的单核苷酸多态性（SNP）与原发性肝细胞癌（HCC）遗传易感性的关系，为筛检肝癌高危人群，以及进行肝癌一、二级预防提供参考依据。 方法 采用病例-对照研究设计，抽样调查在2011年1月至2014年10月间厦门市综合性三甲医院就诊的肝癌患者和健康对照者。病例组纳入标准：根据HCC诊断依据在调查期间被首次确诊为HCC、年龄≥18岁、现住址与调查地属同一区（县）级范围、无任何其他肿瘤史的患者。排除标准：患有HCC以外的肿瘤 ...
潘欢欢
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High nitrogen enrichment buffers plant photosynthesis against herbivory damage
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Herbivorous insects and nitrogen deposition are key drivers of ecosystem productivity under global change. However, their combined effects on plant photosynthesis, particularly during insect outbreaks, remain poorly understood in natural ecosystems.
Yongqiang Zhang +6 more
wiley +1 more source
Robust metrics for quantifying and comparing resistance and recovery in experimental studies
Methods in Ecology and Evolution, EarlyView.Abstract Various indices have been developed to experimentally quantify resistance and recovery (two components of engineering resilience) in response to anthropogenic and natural disturbances. This diversity complicates the selection of appropriate metrics for comparing resilience across ecosystems and studies.
Zewei Zhuang +2 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2004 【目的】为了探讨tau基因多态性与帕金森病的关系。【方法】本实验用PCR-片段长度多态性分析法检测了123例中国散发性帕金森病病人和114个正常对照的微管相关蛋白(tau)基因A0等位基因多态性。【结果】我们发现tau基因A0等位基因和A0/A0基因型在帕金森病组的出现率略高于对照组,分别为77.6%:74.1%和61%:57%,但无统计学意义。【结论】A0多态性与我国散发性帕金森病发病无关。
陶恩祥
doaj
Relationship between NF-κB gene Polymorphisms and Inflammation injure of Hepatitis B [PDF]
, 2017 [目的] 探讨NF-κB基因多态性在乙型病毒性肝炎炎症损伤进展中的影响，为今后有效控制肝脏慢性炎性损伤提供理论依据。 [方法] 于2015年9月-2016年9月收集厦门市中医院肝病科乙肝病毒高载量慢性乙肝住院病例，对所有病例进行问卷调查，了解性别、年龄、HBV感染初次发现年龄、肝脏疾病家族史、吸烟饮酒史等基础资料及乙肝病毒载量、肝脏炎症等级等临床资料，其中慢性乙肝轻型肝炎患者作为对照组，中型及重型肝炎患者作为病例组；采集入组对象空腹外周血5ml，进行病毒载量确认及提取患者DNA样本 ...
王传鹏
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