Results 61 to 70 of about 22,208 (188)

MDR1基因多态性与肝癌易感性的关系 [PDF]

open access: yes, 2009
目的:探讨MDR1基因位点单核苷酸多态性与肝癌易感性的关系。方法:采用病例对照研究,应用聚合酶链反应限制性片段长度多态性(PCR-RFLP)基因型分析技术测定原发性肝癌组及正常健康对照组各100例MDR1基因G2677T/A位点。以χ2检验比较MDR1多态基因型及相关危险在病例与对照之间分布的差异,采用非条件Logistic回归分析多态基因型与肝癌发生危险度的关系。结果:肝癌组MDR1基因2677A携带型低于健康对照组 ...
冯水土, 张永兴, 杨芳, 陈毅德
core  

The Inclusion Trade‐Off: Comparing the Design and Functionality of Collaborative Governance Forums

open access: yesPolicy Studies Journal, EarlyView.
ABSTRACT Environmental challenges require collaboration across jurisdictions, often through forums or intermediary spaces for repeated interaction. A persistent forum design question concerns inclusion criteria, or which actors should be included.
Adam Wiechman   +3 more
wiley   +1 more source

血管紧张素原基因M235T多态性与结直肠癌易感性关系的研究

open access: yesZhongguo shiyan zhenduanxue, 2012
目的探讨血管紧张素原(AGT)基因M235T多态性与中国人群结直肠癌易感性的关系。方法采用聚合酶链反应-限制性片段长度多态性方法检测结直肠癌组151例患者和健康对照组202例AGT基因M235T多态性。结果结直肠癌组与对照组AGT20M235T基因型和等位基因分布差异无统计学意义(P>0.05)。根据临床病理特征进行分层分析,发现携带TT基因型个体患低分化结直肠癌的风险比携带MT/MM基因型高2.50倍(P=0.008,OR=2.50;95%CI,1.26-4.97 ...
侯波
doaj  

[Research advances in genetic polymorphisms in Kawasaki disease]. [PDF]

open access: yesZhongguo Dang Dai Er Ke Za Zhi, 2023
Dong MX, Wang XX, Jiao FY, Zhang WH.
europepmc   +1 more source

降钙素受体基因多态性与老年男性骨密度关系 [PDF]

open access: yes, 2006
[目的]探讨降钙素受体基因(CTR)C1377T基因多态性与老年男性人群骨密度相互关系.[方法]选取年龄≥65岁广州地区汉族男性个体247例,采用双能X线吸收法(DEXA)测定其全身、腰椎2~4(L2~4)、股骨颈(Neck)、粗隆间(Inter)、Ward'三角和大转子(Troch)区等部位的骨密度(BMD)值,并采用聚合酶链反应限制性片段长度多态性(PCR-RFLP)技术检测外周血白细胞基因组降钙素受体基因多态性.[结果]247例受试对象中,CTR基因型分别为CC型205例(83.0 ...
吴文   +7 more
core  

A Tale of Two Programs? Stigma and Administrative Burdens in CHIP and Medicaid

open access: yesWorld Medical &Health Policy, Volume 18, Issue 1, March 2026.
ABSTRACT One contributing factor to undersubscriptions is administrative burdens. To explore whether program stigma affects attitudes about administrative burdens, a survey (N = 2204) was fielded to assess differences in attitudes about seven policies decreasing administrative burdens and two policies increasing administrative burdens.
Simon F. Haeder
wiley   +1 more source

TaqMan-MGB法检测ACTN3基因R577X多态性

open access: yesZhongguo shiyan zhenduanxue, 2017
目的研制检测ACTN3基因R577X多态性的TaqMan-MGB探针方法。方法根据美国国立医学图书馆网站公布的人类ACTN3基因序列(rs1815739),设计检测ACTN3基因R577X多态性的特异引物和TaqMan-MGB探针,建立和优化实验条件。结果对98例西北大学汉族学生进行ACTN3基因R577X多态性检测,并对上述所有检测标本再进行碱基序列测序,两种检测方法的检测结果经Kappa分析,Kappa=0.99。结论两种检测方法结果一致性较好,建立了检测ACTN3基因R577X多态性的TaqMan-
张志明, 高鹏华, 胡辽辽, 马莹
doaj  

Effects of landscape fragmentation on floodplain fishes as revealed by species–habitat networks

open access: yesConservation Biology, Volume 40, Issue 1, February 2026.
Abstract How species interact with habitat patches is influenced primarily by habitat configuration (e.g., connectivity) and species’ functional traits. As levels of fragmentation increase, identifying the intricate connections between these components is crucial for biodiversity conservation.
Chen Zhang   +8 more
wiley   +1 more source

转化生长因子β1基因多态性与食管癌的关系

open access: yesZhongguo shiyan zhenduanxue, 2010
目的研究转化生长因子β1(TGF-β1)基因启动子区-800G/A和第1外显子+915G/C基因多态性各等位基因及基因型在食管癌患者中的分布频率,初步分析其基因型及血清水平与食管癌的相关性。方法采用序列特异性引物聚合酶链反应(PCR-SSP)和聚合酶链反应-限制性片段长度多态性(PCR-RFLP)技术,检测118例食管癌患者和130例正常对照组TGF-β1的基因多态性,包括TGF-β1基因启动子-800G/A、第1外显子+915G/C位点,同时采用酶联免疫吸附试验(ELISA)检测血清TGF-β1水平 ...
唐任光   +5 more
doaj  

Genetic origins and climate‐induced erosion in economically important Asian walnuts

open access: yesConservation Biology, Volume 40, Issue 1, February 2026.
Abstract The global climate is undergoing unprecedented changes, posing significant threats to species persistence. However, the spatiotemporal impacts on genetic diversity remain poorly understood, hindering species conservation and management. Walnuts, generally referred to as Juglans regia and J. sigillata, are economically vital in Asia, but little
Peng‐Zhen Fan   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy