Results 11 to 20 of about 16,526 (215)

Transformation of social‐ecological systems in the Songhua River Basin, Northeast China: Lessons for a more sustainable development

open access: yesPeople and Nature, Volume 7, Issue 7, Page 1749-1768, July 2025.
Abstract Social‐ecological systems (SES) are coupled systems formed by the intricate interactions between humans and nature. Our movement towards sustainable lifestyles requires a robust understanding of these interactions. Achieving a sustainable win‐win situation for both social and ecological systems, therefore, necessitates a sound scientific ...
Na Sa   +6 more
wiley   +1 more source

Simple sequence repeats and their expansions: role in plant development, environmental response and adaptation

open access: yesNew Phytologist, Volume 247, Issue 2, Page 504-517, July 2025.
Summary Repetitive DNA is a feature of all organisms, ranging from archaea and plants to humans. DNA repeats can be seen both in coding and in noncoding regions of the genome. Due to the recurring nature of the sequences, simple DNA repeats tend to be more prone to errors during replication and repair, resulting in variability in their unit length ...
Sridevi Sureshkumar   +3 more
wiley   +1 more source

Breaking the Mold: Brazil's Foreign Policy Insights

open access: yesLatin American Policy, Volume 16, Issue 2, June 2025.
ABSTRACT Brazilian foreign policy studies have traditionally focused on the institutional role of Itamaraty, often overlooking the influence of academia in shaping diplomatic debates. While the Ministry of Foreign Affairs has historically led policy formulation, academic actors have contributed with intellectual frameworks that shape diplomatic ...
Diego S. Crescentino
wiley   +1 more source

Intragenic PNPLA1 duplication in Labrador retrievers with nonepidermolytic ichthyosis

open access: yesVeterinary Dermatology, Volume 36, Issue 3, Page 314-320, June 2025.
Background – Ichthyoses represent a heterogeneous group of cornification disorders characterised by epidermal scaling. Objectives – To describe the clinical, histopathological and genetic analysis of a Labrador retriever with nonepidermolytic ichthyosis, and the results of a Labrador retriever population screening for a newly detected PNPLA1 genomic ...
Stefan J. Rietmann   +7 more
wiley   +1 more source

Essential skills for the training of conservation social scientists

open access: yesConservation Biology, Volume 39, Issue 2, April 2025.
Abstract Since 2000, the field of biodiversity conservation has been reckoning with the historical lack of effective engagement with the social sciences in parallel with rapid declines in biodiversity and escalating concerns regarding socioecological justice exacerbated by many common conservation practices.
Laura Thomas‐Walters   +9 more
wiley   +1 more source

Social protection and resilience in protracted crises

open access: yesInternational Social Security Review, Volume 78, Issue 2-3, Page 173-190, April-September 2025.
Abstract This article critically examines perspectives on social protection’s role in strengthening resilience capacities in protracted crises – contexts where conflict and displacement persist for five years or longer. These crises shape how stakeholders navigate their mandates to provide support, while influencing how affected communities seek to ...
Carolina Holland‐Szyp, Jeremy Lind
wiley   +1 more source

The research of the detection of thalassaemia multiple mutations by next-generation sequencing technology [PDF]

open access: yes, 2015
地中海贫血又称珠蛋白生成障碍性贫血,早期的病例来自地中海地区,故称为地中海贫血,是世界范围内影响最大的单基因病之一,遵循孟德尔遗传定律。该病是由珠蛋白基因的缺失或点突变所致,根据其变异的肽链可分为α地贫和β地贫。由于其基因缺陷的复杂、多样,使缺乏的珠蛋白链类型、数量、临床症状变异较大。临床上对中、重度地中海贫血无行之有效的治疗方法,给社会、家庭、个人带来了沉重的经济及精神负担。故有效检出地中海贫血患者、进行婚前孕前指导、产前诊断、避免地中海贫血患儿的出生,有着极其重要的社会意义 ...
成明
core  

Lessons for Transboundary Snow Leopard Conservation: Findings From a GPS Telemetry Study in Kangchenjunga Conservation Area, Nepal 跨境雪豹保护经验:来自尼泊尔Kangchenjunga保护区的GPS追踪研究结果

open access: yesIntegrative Conservation, Volume 4, Issue 1, Page 45-56, March 2025.
Understanding the spatial ecology and movement of snow leopards is crucial for their long‐term conservation. Our first GPS telemetry study in Nepal revealed that snow leopards of Nepal have much larger home ranges than previously thought and frequently cross international borders.
Samundra Ambuhang Subba   +21 more
wiley   +1 more source

中国南方三个Hunter综合征家系的病因学研究

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2023
目的揭示中国南方3个Hunter综合征家系的分子发病机制,阐明患者表型和基因型的相关性,为今后的产前或植入前基因诊断奠定基础。方法在临床初诊和系谱分析的基础上,首先进行尿糖胺聚糖定性检测,然后抽取患儿及其亲属的抗凝血,提取DNA并通过PCR、Sanger测序对IDS基因进行序列分析。对发现的新变异采用RT-PCR和生物信息分析等多种方法进行致病性鉴定。结果3个家系的患者尿检结果均为强阳性(++)。家系1~3先证者为男性,IDS基因均发生半合子突变且突变均来自其母,突变位点分别为:c ...
郑诗瑶   +6 more
doaj  

The fMRI study of the hypothalamus function in the patients with pituitary adenoma before and after operation [PDF]

open access: yes, 2015
目的:利用静息态功能磁共振影像记录技术,以垂体腺瘤患者手术前后的下丘脑区为研究对象,探讨下丘脑区功能变化与垂体腺瘤的相关性。 方法:连续性收集自2013年1月至2014年2月来我院神经外科就诊的剔除不符合标准后的78例垂体腺瘤患者进行本课题研究。纳入标准:①具有完整的诊疗记录,包括术前、术后MRI(含fMRI)检查,术前及术后1天、3天、7天、1个月、6个月的激素检测,术中完整手术录像、手术记录、日常病程记录及护理记录;②术后经过病理学(免疫组织化学法)检测后确定为垂体腺瘤的患者;排除标准 ...
肖勇
core  

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