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HIF-1α治疗家兔肢体缺血模型的实验研究

Zhongguo shiyan zhenduanxue, 2008
目的探讨缺氧诱导因子（HIF-1α）基因治疗家兔肢体缺血模型的疗效。方法在家兔缺血模型的肢体内注射携带/HIF-1α基因的重组腺病毒AdHIF-1α,检测HIF-1α基因在缺血肌组织中表达情况,并观察其生物学特点。实验以携带GFP基因的重组腺病毒AdGFP为对照。结果免疫组化染色均检测到HIF-1α的表达。转AdHIF-1α基因治疗组毛细血管计数及小动脉计数均高于AdGFP转导的对照组 ...
孙晓峰, 谭岩, 董春哲, 王琦, 方艳秋, 王中英   +5 more
doaj  

Genomic insights into the diversity of rice cultivars developed in Heilongjiang Province, China. [PDF]

J Zhejiang Univ Sci B
Zhou Y, Liu N, Yang J, Chen B, Li C, Bu F, Wu S, Zhou Z, Yu Q, Shu Q.   +9 more
europepmc   +1 more source

[Diagnostic value of intestinal tissue metagenomic next-generation sequencing in severe diarrhea following haploidentical hematopoietic stem cell transplantation]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Lin QX, Wei JJ, Lian TT, Lin BQ, Ren JH, Zheng XY, Wu XQ, Li J, Chen H, Xie SJ, Yang T.   +10 more
europepmc   +1 more source

[Diagnosis of mucormycosis in three children following hematopoietic stem cell transplantation using metagenomic next-generation sequencing]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Li Y, Zhou XH, Wang XD, Wang CJ, Cao K, Liu SX.   +5 more
europepmc   +1 more source

Efficient genome editing in medaka (Oryzias latipes) using a codon-optimized SaCas9 system. [PDF]

J Zhejiang Univ Sci B
Jiang Y, Pan Q, Wang Z, Lu K, Xia B, Chen T.   +5 more
europepmc   +1 more source

Global analysis of DNA methylation changes during experimented lingual carcinogenesis. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi
Liu H, Yue W, Shao S, Sun J, Yang Y, Dai X.   +5 more
europepmc   +1 more source

Radiogenomics-based prediction of <i>KRAS</i> and <i>EGFR</i> gene mutation in non-small cell lung cancer patients. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Lin J, Yan Z, He L, Zhang H, Xie M.
europepmc   +1 more source

[Mechanisms of Wandai Decoction in Improving Vaginal Flora of Vulvovaginal Candidiasis of the Spleen Deficiency and Excessive Dampness Type: A Study Based on Metagenomics and Metabolomics]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Han Y, Shen S, Fu J, Ren Q.
europepmc   +1 more source

Impact of interaction between individual genomes and preeclampsia on the severity of autism spectrum disorder symptoms. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Wang X, Wu D, Luo T, Fan W, Li J.
europepmc   +1 more source

[Application of metagenomic next-generation sequencing technology in preterm infants with sepsis following antibiotic use]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Lou CY, Liu YN, Zhang X, Guo YY, Zhang L.   +4 more
europepmc   +1 more source