Results 21 to 30 of about 10,299 (119)
ABSTRACT The healing of diabetic chronic wounds is hindered by multiple pathological barriers, including oxidative stress imbalance induced by hyperglycemia, persistent bacterial infection, and impaired neovascular function. This study developed an F127–HA–BiOCl@CeO2 (FHBC) hydrogel dressing with acoustic responsiveness, achieving tissue repair through
Ran Zhao +8 more
wiley +1 more source
ABSTRACT Infected bone defects represent a dual therapeutic challenge demanding concurrent infection inhibition and osteogenesis promotion. Systemic antibiotic administration is taken as a classical treatment protocol but often yields inadequate local antibiotic concentrations and delayed bone repair.
Xucai Wang +8 more
wiley +1 more source
Abstract Constructed value of information (CVoI) is an expert elicitation decision‐analytic tool used to prioritize sources of uncertainty based on their potential to improve decision outcomes if resolved. Despite increased application of CVoI, the robustness of CVoI prioritization of sources of uncertainty relative to differences in expert elicitation
Kristin P. Davis +7 more
wiley +1 more source
Abstract Bycatch in fisheries is one of the most serious threats to pelagic seabirds, causing major population declines. Mitigation measures can reduce bycatch substantially, but many fisheries fail to apply best practices, and seabird mortality remains high.
V. Warwick‐Evans +2 more
wiley +1 more source
Assessing differences among elasmobranch nurseries to aid conservation based on a genomics framework
Abstract Elasmobranch nurseries often differ in environmental conditions, demographics, and use patterns. These differences affect the distribution of genetic variation among nurseries. However, conservation and management strategies often fail to account for such differences because they are difficult to characterize.
Dominic G. Swift +8 more
wiley +1 more source
原发性肝癌属于常见的恶性肿瘤,临床发病率与死亡率均较高。特别是肝炎病毒感染,是诱发原发性肝癌的重要因素。目前阶段,国内以乙型肝炎病毒为主,在单染病毒感染后,会严重损伤肝脏,导致干细胞半持续性增殖[1]。一旦细胞增殖速度加快,就会增加干细胞增殖周期当做调控基因的改变几率[2 ...
史立英 +4 more
doaj
ABSTRACT Objective Infertility affects up to 20% of couples in high‐income countries, which has led to an increased use of assisted reproductive technology (ART). While previous studies have linked ART to a higher risk of major congenital heart defects (CHD), less is known about the associated risk of minor CHD.
F. Kyhl‐Svart +16 more
wiley +1 more source
We developed an effective ex‐situ conservation approach for an endangered orchid species, Dendrobium sinominutiflorum. A compatible fungal strain Tulasnella sp. was obtained by using in‐situ seed baiting technique. The Symbiotic germination with Tulasnella sp. significantly promotes seed germination and seedling growth.
Han‐Xiao Huang +6 more
wiley +1 more source
【目的】观察miR-34a在低氧诱导的大鼠肺动脉平滑肌细胞增殖中的作用并探讨其可能的机制。【方法】原代分离和培养大鼠肺动脉平滑肌细胞(PASMC),并给予3%低氧处理后,用Real-time PCR法检测miR-34a和Notch1mRNA在大鼠PASMC中的表达;低氧条件下用细胞转染法过表达和抑制miR-34a、沉默Notch1基因的表达后用EDU法观察细胞增殖情况,并用Real-time PCR和Western blot法检测细胞核增殖抗原PCNA的表达。【结果】分离和培养大鼠PASMC并给予3 ...
马兰
doaj
ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun +8 more
wiley +1 more source

