Results 31 to 40 of about 7,319 (164)
The value of exosomes suppressor of cytokine signaling 1， speckled protein 140 and calcyclin binding protein expressions in peritoneal dialysis effluent in the diagnosis of peritoneal fibrosis [PDF]
ObjectiveTo investigate the value of suppressor of cytokine signaling 1 （SOCS1）， speckled protein 140 （SP140）， calcyclin binding protein （CacyBP） expressions in peritoneal dialysis effluent in the diagnosis of peritoneal fibrosis （PF）.MethodsA total of ...
Cao Yan-chun +7 more
core +1 more source
New Phytologist, Volume 247, Issue 1, Page 369-387, July 2025.Summary The butterfly‐shaped keel flower is a highly successful floral form in angiosperms. These flowers steer the mechanical interaction with bees and thus are hypothesized to accelerate pollinator‐driven diversification. The exceptionally labile evolution of keel flowers in Papilionoideae (Fabaceae) provides a suitable system to test this hypothesis.
Liming Cai +10 more
wiley +1 more source
The function of miR-411-5p in proliferation and metastasis of breast cancer cells [PDF]
, 2017 MicroRNA（miRNA）是真核生物中一类小的内源性非编码单链RNA，通过靶向作用于信使RNA（mRNA），其在基因的转录和翻译过程中起到至关重要的作用。MiR-411-5p（之前又被称为miR-411）与人类许多疾病的发生发展相关。然而，miR-411-5p与乳腺癌的关系至今未被研究透彻。本研究中，我们发现，相对于正常乳腺组织，miR-411-5p在乳腺癌中是低表达的；同时，与正常乳腺细胞MCF-10A相比，miR-411-5p在乳腺癌细胞系中也是低表达的。本研究发现，在乳腺癌细胞中过表达miR ...
张运达
core
CRABS CLAW‐independent floral nectary development in Penstemon barbatus
American Journal of Botany, Volume 112, Issue 6, June 2025.Abstract Premise Plants secrete carbohydrate‐rich nectar from specialized floral nectary glands to attract pollinators. Arabidopsis and Petunia (rosid and asterid core eudicots, respectively) share genetic control of nectary development requiring activation of CRABS CLAW by euAGAMOUS and PLENA.
Amanda M. Katzer +3 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2016 外泌体最初是由Johnstone等在哺乳动物网织红细胞研究中发现并命名[1-6]。后来的研究发现,外泌体在细胞内形成小囊泡,可以通过胞吐释放到周围环境中,并能够在血液、尿液等多种体液中检测到[7]。外泌体中携带着它本身来源的细胞的多种成分,如蛋白质、DNA、RNA、脂质等[8]。因此,建立稳定的外泌体分离方法是外泌体以及后续相关研究的前提 ...
周玄博 +5 more
doaj
Effects of exosomes of paratumoral thymus epithelial cells on Treg cell function in patients with thymoma-associated myasthenia gravis [PDF]
Objective To investigate the effects of exosomes derived from paratumoral thymic epithelial cells on the expression of forkhead box protein P3 (FOXP3) and the secretion of transforming growth factor-beta1 (TGF-β1) and interleukin (IL)-10 by regulatory T ...
BAO Xiaoran +4 more
core +1 more source
The developmental basis of floral nectary diversity and evolution
New Phytologist, Volume 246, Issue 6, Page 2462-2477, June 2025.Summary Nectar is a central bridge between angiosperms and animal mutualists. It is produced by specialized structures termed nectaries, which can be found on different plant organs. Consumption of floral nectar by pollinators and the subsequent transfer of pollen contribute to the reproductive success of both angiosperms and their pollinators.
Irene T. Liao +3 more
wiley +1 more source
, 2018 过去近半个世纪的研究表明,间充质干细胞(MSCs)作为肿瘤微环境中细胞成份的重要成员之一,它在肿瘤细胞生长增殖、凋亡调控、侵袭性生长和转移、血管新生、能量代谢以及治疗抗性等诸多恶性生物学特性中均发挥重要的生物学作用,其相关的分子机制也逐步被揭示;相应地,基于这些发现的基因工程修饰和物理(化学)预处理的MSCs在特定肿瘤综合治疗中临床应用研究也取得了令人振奋的结果。本文就目前MSCs在恶性肿瘤发生发展中所起的生物学作用及其分子机制研究的相关进展作一综述 ...
任群, 林婷婷, 王水良
core
Mechanism of alternative splicing in gene transcription and research progress in head and neck squamous cell carcinoma [PDF]
, 2023 Misregulation of alternative splicing may result in splicing defects in different types of cancers under multiple pathological conditions. Alternative splicing events may serve as potential molecular markers during the diagnosis and treatment for cancer.
Meng Guangxue, Ma Hong, Liao Dezhong
core +1 more source
American Journal of Botany, Volume 112, Issue 4, April 2025.Abstract Premise Uncarina contains 14 species of woody plants endemic to Madagascar. Its occurrence across dryland biomes on the island make it an interesting system to study the diversification of the flora. Methods Using samples of all species and 512 nuclear loci, we reconstructed phylogenetic trees to examine species relationships and assess their ...
Jeffrey P. Rose +3 more
wiley +1 more source