Relationship between IL-17A gene polymorphism and susceptibility to Kawasaki disease. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Yang Y +5 more
europepmc +1 more source
A link between increased temperature and avian body condition in a logged tropical forest
Conservation Biology, EarlyView.Abstract The combined effects of anthropogenic disturbances, such as logging and climate change, remain poorly understood; yet, they are the main threats to tropical biodiversity. Most tropical African countries lack long‐term climate data, so climate impacts on biodiversity cannot be assessed.
Moreen Uwimbabazi +7 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 1998 调查上海部分地区正常人血清ａｐｏＥ浓度，了解它与年龄和性别的关系；建立ａｐｏＥ基因型的检测方法。方法采用夹心ＥＬＩＳＡ法进行ａｐｏＥ定量，应用多聚酶链反应（ＰｏｌｙｍｅｎａｓｅｃｈａｉｎｒｅａｃｔｉｏｎＰＣＲ）和限制性片段长度多态性分析（ＲｅｓｔｒｉａｔｉｏｎｆｒａｇｍｅｕｔｌｅｎｇｔｈＰａｌｙｍｏｒｐｈｉｓｍ，ＲＦＬＰ）建立ａｐｏＥ多态性分析法。结果２００份正常人血清ａｐｏＥ定量确立参考值范围为８０±５３ｍｇ／Ｌ，女性略高于男性，不同年龄无显著差异；建立了快速抽提ＤＮＡ方法和ＰＣＲ扩增及ＲＦＬＰ法 ...
沈霞 +3 more
doaj
[Association between HLA-DRB1 gene polymorphisms and genetic susceptibility of early-onset severe preeclampsia]. [PDF]
Zhongguo Dang Dai Er Ke Za Zhi, 2023 Lai CC +4 more
europepmc +1 more source
The effect of pentosan polysulfate on diabetic nephropathy renal tubular epithelial cells injury through regulating p38 MAPK signaling pathway [PDF]
, 2016 目的：观察戊糖多硫酸钠是否通过调控P38MAPK干预糖尿病肾病肾小管上皮细胞的损伤。方法：利用不同浓度（10mmol/L～50mmol/L）葡萄糖刺激肾小管上皮细胞（HK-2）48h，应用CCK-8比色法检测肾小管上皮细胞增殖的改变。利用不同时间段（0h～48h）葡萄糖刺激细胞，用Westernblot法检测P38MAPK蛋白的表达水平。分为正常对照组（control组）、高糖组（HG组，葡萄糖30mmol/L)、戊糖多硫酸钠（PPS）组（PPS200µg/mL)、高糖＋戊糖多硫酸钠组（HG＋
张天英
core
Distribution, scale, and drivers of mass mortality events in Europe's freshwater bivalves
Conservation Biology, EarlyView.Abstract Mass mortality events (MMEs) are decimating populations and compromising key ecosystem functions around the globe. One taxon particularly vulnerable to MMEs is freshwater bivalve mollusks. This group has important ecosystem engineering capacities and includes highly threatened and highly invasive taxa.
Daniel A. Cossey +39 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2011 【目的】研究EXT1与EXT2基因在我国南方正常人及致病性突变已明确的遗传性多发性骨软骨瘤病人中的多态性。【方法】 选取50例中国南方健康汉族个体及13例致病突变已明确的遗传性多发性骨软骨瘤病人，提取基因组DNA，对包含5’UTR区、编码区、外显子-内含子交界区及3’UTR区的PCR产物进行直接测序。 鉴定基因内的遗传变异，并将结果和国际数据库中的数据进行对比。【结果】 在所有研究对象中共发现15个不同的EXT1基因的单核苷酸多态性(SNPs)：3个在编码区，为同义突变，11个在内含子区，1个在3 ...
doaj
[Association of gene polymorphisms of MyD88 and TICAM1 and their interactions with community-acquired pneumonia in children]. [PDF]
Zhongguo Dang Dai Er Ke Za Zhi, 2023 Yang Y, Yang SY, Chen ZB, Liu L.
europepmc +1 more source
Generation and Characterization of HCMV Specific Human Antibody to Explore Antibody Response Profile in HCMV Naturally Infected Individuals [PDF]
, 2015 人巨细胞病毒（Humancytomegalovirus，HCMV）是一种常见的疱疹病毒，在人群中普遍感染，儿童感染率约为10%-40%，成人为50%-90%，大部分感染者为无临床症状的健康人。但机体免疫功能低下的人群如器官移植患者及AIDS病人，更易发生HCMV病毒的新发或复发感染，引起致命疾病如肺炎、肝炎、脑炎等，从而导致器官移植失败及术后死亡；同时HCMV病毒也是宫内感染中危害最大的病毒之一，感染率占怀孕妇女的0.5%-2%，尤其是在发展中国家较为常见，孕妇感染后自身多无明显症状或轻微症状 ...
夏琳
core
How much biotic nativeness matters across human demographic groups
Conservation Biology, EarlyView.Abstract Many central concepts of conservation biology—such as nativeness—are structured by ecological and social factors. However, the social consequences of using these concepts to make conservation decisions remain inadequately understood. Some researchers argue that nativeness, rather than acting as an objective proxy for important ecological ...
Harold N. Eyster, Rachelle K. Gould
wiley +1 more source