Results 11 to 20 of about 1,500,514 (193)

儿童持续性蛋白尿血管紧张素转换酶基因多态性的研究

open access: yesZhongguo shiyan zhenduanxue, 2003
目的 探讨儿童持续性蛋白尿与血管紧张素转换酶基因多态性的关系。方法 用PCR方法检测了 186例儿童持续性蛋白尿患儿ACE基因多态性及ACE基因多态性与尿蛋白量、血尿、高血压、氮脂血症的关系。结果 持续性蛋白尿患儿ACE -DD基因频率为 0 .2 0 ,II基因频率为 0 .5 2 ,DI基因频率为 0 .2 8;持续性蛋白尿患儿ACE基因多态性与正常对照组存在明显差异 ;尿蛋白量与ACE基因多态性有关 ,大量蛋白尿多为ACE -II型 ;在紫癜性肾炎组血尿的发生以II型为主 ...
李丽红   +5 more
doaj  

Insights for conservation from the Ecological Knowledge Games project

open access: yesConservation Biology, EarlyView.
Abstract Environmental conservation research requires robust methods for collecting large‐scale behavioral data and engaging diverse stakeholders in decision‐making processes. We (Y.P., A.B.D., and N.B.) created EcoKnowGames (Ecological Knowledge Games), a transdisciplinary project that develops knowledge games for conservation science and data ...
Yuan Pan   +4 more
wiley   +1 more source

谷胱甘肽巯基转移酶基因多态性在原发性肝细胞癌人群中的研究

open access: yesZhongguo shiyan zhenduanxue, 2012
目的探讨原发性肝细胞癌人群中谷胱甘肽巯基转移酶基因多态性与肝癌发生、发展的关系。方法我院2008年10月-2010年4月收治的原发性肝癌患者与健康体检者各150名,提取血样,利用多重PCR和限制性片段长度多态性检测法分别检测肝癌人群与体检健康者的谷胱甘肽巯基转移酶基因多态性,并进行对比分析。结果该肝癌人群中:谷胱甘肽巯基转移酶基因多态性型别在病例和对照组研究对象中出现的频率无显著性差别,P>0.05;GSTM1-null、GSTT1-null、GST01-Ala140Asp、GSTP1 ...
唐耘天   +5 more
doaj  

Scientists’ warning on the global destruction of rock outcrop ecosystems

open access: yesConservation Biology, EarlyView.
Abstract Rock outcrops are geological formations that harbor a highly specialized biota adapted to harsh environmental conditions that differ from their surrounding landscapes. They are globally distributed, especially in old, highly weathered landscapes, and can function as habitat islands containing high levels of endemism and distinct evolutionary ...
Luiza F. A. de Paula   +19 more
wiley   +1 more source

E-选择素基因rs3917422A和rs5355C位点多态性与哈尼族原发性高血压相关性研究

open access: yesZhongguo shiyan zhenduanxue, 2009
目的探讨E-选择素基因rs3917422A\C和rs5355C\T位点多态性与哈尼族原发性高血压的关系。方法采用PCR测序技术,对云南哈尼族172例原发性高血压患者和133例正常对照的E-选择素基因rs3917422A\C和rs5355C\T的错义突变进行检测。结果在哈尼族中未发现有rs3917422A多态存在,发现rs5355C基因有多态存在。rs5355C等位基因频率在原发性高血压组中为10.5%,正常对照组中为13.2%,两组之间无显著性差异(P=0.311,P>0.05)。结论哈尼族中E ...
黎曼侬   +6 more
doaj  

Twelve principles for successful governance of community‐based coastal marine restoration

open access: yesConservation Biology, EarlyView.
Abstract Global agreements, such as the Global Biodiversity Framework, call for urgent, large‐scale action to halt biodiversity loss through a whole‐of‐society approach. Community‐based restoration can play a crucial role in achieving this goal, yet there remains limited understanding of what makes these projects effective and sustainable.
Michelle M. Holian   +2 more
wiley   +1 more source

Integrating fossil data in ecological niche models to improve predictions of future habitat of Caribbean corals

open access: yesConservation Biology, EarlyView.
Abstract Ecological niche models (ENMs) are used to assess the abiotic preferences of species by linking their occurrences to the environmental conditions in which they live. We developed a fossil‐informed ENM framework that integrates mid‐Holocene and modern occurrences to test niche stability and reconstruct abiotic niche characteristics for four ...
Claire. M. Williams   +3 more
wiley   +1 more source

Fbgβ455基因多态性与CRP协同作用对动脉粥样硬化的影响

open access: yesZhongguo shiyan zhenduanxue, 2010
目的研究血浆纤维蛋白原Fbgβ455基因多态性与此反应蛋白CRP的协同作用对动脉粥样硬化的影响。方法采用限制性长度多态性聚合酶链反应检测血浆Fbgβ455基因态性及免疫比浊法检测CRP。结果心肌梗塞组与冠心病组患者外周血基因组DNAFbgβ455多态性分布G/G,G/A,A/A具有显著性差异(P0.05)。结论血浆Fbgβ455等位基因型G/A,A/A可能是急性心肌梗塞发病的遗传性危险因素,Fbgβ455与CRP在动脉硬化的发生过程中无协同作用。
孙晓盈, 王海, 高申, 谢风
doaj  

Assessing and strengthening community‐based coastal governance

open access: yesConservation Biology, EarlyView.
Abstract Community‐based coastal governance is essential for biodiversity conservation and sustainable livelihoods, yet many communities continue to face significant challenges in establishing and sustaining effective governance systems. We sought to improve understanding of the current status of community‐based coastal governance across five countries
Mark Andrachuk   +21 more
wiley   +1 more source

血管紧张素原基因M235T多态性与结直肠癌易感性关系的研究

open access: yesZhongguo shiyan zhenduanxue, 2012
目的探讨血管紧张素原(AGT)基因M235T多态性与中国人群结直肠癌易感性的关系。方法采用聚合酶链反应-限制性片段长度多态性方法检测结直肠癌组151例患者和健康对照组202例AGT基因M235T多态性。结果结直肠癌组与对照组AGT20M235T基因型和等位基因分布差异无统计学意义(P>0.05)。根据临床病理特征进行分层分析,发现携带TT基因型个体患低分化结直肠癌的风险比携带MT/MM基因型高2.50倍(P=0.008,OR=2.50;95%CI,1.26-4.97 ...
侯波
doaj  

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