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虎杖中白藜芦醇和大黄素的高效提取技术研究

, 2016
虎杖是一种重要的传统中药材，在东南亚地区有着悠久的应用历史。白藜芦醇和 大黄素作为虎杖中的两种主要有效成分，具有多种药理活性。在虎杖中白藜芦醇和大黄素主要以糖苷形式存在，但糖苷的生物利用度和活性均小于其苷元。因此，有必要将糖苷进行水解以提高虎杖中白藜芦醇和大黄素的得率。目前，关于白藜芦醇苷的水解已有许多报道，但其水解的动力学和机制等仍缺乏深入的研究。本学位论文开展了白藜芦醇苷的酸水解动力学研究；并在此基础上，开发了一种高效的同时提取和水解的方法用于获得虎杖中白藜芦醇和大黄素 ...
刘芬
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