Regulation of bioactive peptides of oyster(BPO)on the cell cycle and gene expression of human gastric adenocarcinoma cell-line BGC-823 [PDF]
目的比较研究牡蛎天然活性肽(BPO)对人胃腺癌BGC-823细胞凋亡的生物学效应,并进一步探索其对胃癌细胞的作用机制。方法采用酸抽提、凝胶柱层析等方法,从牡蛎体内分离提取到牡蛎天然活性多肽组分BPO-1,以姜黄素和HMBA处理组为平行对照,流式细胞仪检测细胞周期变化及以免疫细胞化学方法检测相关癌基因、抑癌基因表达变化。结果BPO-1能有效抑制BGC-823细胞增殖活动,出现亚G1期细胞,细胞进入凋亡现象。BPO-1,姜黄素及其组合均能不同程度地上调BGC-823细胞p16,c-myc,Fas ...
李祺福, 李鹏, 梁盈, 石松林
core
Effect of Curcumin on Physicochemical and Gel Properties of Pork Myofibrillar Proteins under Oxidative Condition [PDF]
To explore the effects of different curcumin concentrations on the gel properties of pork myofibrillar proteins (MPs), changes in gel whiteness, cooking loss, water retention capacity, texture, dynamic rheology, intermolecular forces, microstructure, and
CHANG Haijun, SHI Yuanwei, BO Zhaoying, ZHOU Wenbin, HU Yu
core +1 more source
Preparation of Hydrogel Films Loaded with Curcumin-Zinc Oxide Nanoparticles and Its Preservation Effect on Low-temperature Chilled Chicken Meat [PDF]
This study aimed to extend the shelf-life of chilled chicken meat by preparing curcumin-zinc oxide nanoparticles (CUR-ZnO NPs) using curcumin and zinc oxide.
Long DU +5 more
core +1 more source
Study on the changes of nuclear matrix proteins during the apoptosis of the osteosarcoma MG-63 cells [PDF]
本文在鉴定姜黄素(curcumin,Cur)诱导人成骨肉瘤MG-63细胞凋亡的基础上,应用选择性抽提整装透射电镜和蛋白质组学分析技术,对MG-63细胞诱导凋亡过程中核基质-中间纤维系统的构型变化和核基质蛋白组成的变化进行系统研究。分析鉴定与肿瘤细胞凋亡相关的特异核基质蛋白,并探索它们在肿瘤细胞凋亡过程中的调控作用,以期能够在较为整体的水平上进一步认识肿瘤细胞凋亡及其机理,从而找出肿瘤细胞凋亡研究的新方向。实验结果显示,经7.5μg/mL姜黄素处理之后,人成骨肉瘤MG-63细胞的增殖受到明显抑制 ...
郑燕彬
core
Curcumin alleviates myocardial inflammatory responses by inhibiting Wnt5a/β-Catennin pathway after coronary microembolization in rats [PDF]
Objective To explore the potential mechanisms of curcumin on myocardial inflammatory responses following coronary microembolization (CME) in rats. Methods Thirty-two SD rats were randomly divided into a sham group, a CME group (model group), a CME ...
LI Lang +4 more
core +1 more source
[Curcumin induces human lens epithelial cell apoptosis and cell cycle arrest by inhibiting Wnt/β-catenin signaling pathway]. [PDF]
Zhu M +7 more
europepmc +1 more source
【目的】观察姜黄素对兔单肺通气导致的肺损伤的影响。【方法】12只新西兰白兔随机分为单肺通气组(组Ⅰ)和单肺通气+姜黄素组(组Ⅱ),每组6只。于实验前七天开始灌胃给药,组Ⅰ给予对照剂,组Ⅱ给予姜黄素40mg/kg,每天早晚各一次。两组动物均气管切开插入单腔气管导管(ID:3.5mm)建立右侧单肺通气模型,采用容量通气模式(潮气量 12 mL/kg,呼吸频率40 min-1,I:E=1:2)并模拟左侧开胸手术。先双肺通气30min,再单肺通气3h,恢复双肺通气30min。监测两组兔血气及气道峰压 ...
doaj
Research Progress on Photodynamic Antifungal Technology [PDF]
Fungal pathogens pose serious threats in the food field, not only causing food spoilage, but also potentially causing foodborne illnesses, thereby leading to food safety and public health issues.
CHEN Miaofeng, YANG Haoqing, LU Yihui, HU Jiamiao, LIN Shaoling
core +1 more source
[Effects of calcium phosphate cement combined with hyaluronic acid/curcumin on the proliferation and osteogenesis of osteoblasts]. [PDF]
Zhang Y +6 more
europepmc +1 more source
Preliminary Research on Roles of Special Nuclear Matrix Proteins during Apoptosis of Human Esophageal Cancer EC9706 Cells [PDF]
本论文以姜黄素(curcumin,Cur)处理人食管癌EC9706细胞,在鉴定姜黄素对人食管癌EC9706细胞凋亡诱导效果的基础上,综合应用亚细胞蛋白质组学分析、免疫细胞化学、细胞分子生物学等技术,对EC9706细胞凋亡过程中核基质蛋白的变化进行了较为系统的研究。分析鉴定和确证与EC9706细胞凋亡相关的特异核基质蛋白,并研究特异核基质蛋白与人食管癌EC9706细胞凋亡相关基因在细胞内的共定位关系与变化,探索它们在人食管癌细胞凋亡诱导过程中的调控作用 ...
刘用金
core

