Results 21 to 30 of about 1,893,250 (143)
应用CSC-GE-80基因芯片筛查人子宫内膜早期异位种植的血管生长相关基因 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2007 【目的】探讨子宫内膜异位早期种植的相关基因,特别是与早期种植相关的血管生长基因。【方法】采用裸鼠人子宫内膜皮下种植的方法,建立裸鼠人子宫内膜异位症模型,在种植后14d,取出成模病灶与未种植内膜进行CSC-GE-80基因芯片筛查比较。【结果】在基因表达谱中最有显著性上调基因50个,最有显著性下调基因47个,包括生长因子和细胞因子及其受体的变化,其中生长因子受体结合蛋白10（growth factor receptor-bound protein10,Grb10）与丁酸盐反应因子1（butyrate ...
王宁宁 +9 more
doaj +1 more source
Prevalence of adenomyosis in women with subfertility: systematic review and meta‐analysis
Ultrasound in Obstetrics &Gynecology, Volume 62, Issue 1, Page 23-41, July 2023., 2023 ABSTRACT Objective To determine the prevalence of adenomyosis in women with subfertility. Methods A systematic search was conducted in MEDLINE, EMBASE, CINAHL Plus, Google Scholar, PsycINFO and Web of Science Core Collection from database inception to October 2022. The included studies evaluated the prevalence of adenomyosis in women with subfertility,
I. Mishra +5 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 60, Issue 4, Page 477-486, October 2022., 2022 ABSTRACT Objective The aim of this systematic review and meta‐analysis was to evaluate the diagnostic accuracy of the sliding sign on transvaginal ultrasound (TVS) in detecting pouch of Douglas obliteration and bowel involvement in patients with suspected endometriosis, using laparoscopy as the reference standard.
J. L. Alcázar +6 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 探索建立人子宫内膜异位症荧光体外与在体模型的具体方法65377;【方法】 采用增强型绿色荧光蛋白腺病毒(Ad-eGFP)分别转染原代培养人子宫内膜腺上皮细胞和基质细胞(细胞转染注射法,即方法1)和子宫内膜组织块(组织转染注射法,即方法2),比较两种体外转染的差异;然后采用方法1将绿色荧光腺病毒转染后的腺上皮细胞和基质细胞注入裸鼠皮下形成荧光病灶,并且与方法2相比较,观察直至建模后25 d,计算病灶荧光成模率与病灶荧光存在时间,并给予组织鉴定65377;【结果】 方法1与2建模后5 ...
doaj +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 60, Issue 1, Page 118-131, July 2022., 2022 ABSTRACT Objectives To evaluate whether the Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis need to be better defined and, if deemed necessary, to reach consensus on the updated definitions. Methods A modified Delphi procedure was performed among European gynecologists with expertise in ultrasound diagnosis of adenomyosis. To
M. J. Harmsen +17 more
wiley +1 more source
, 2023 目的为了探索杂交捕获二代测序技术在子宫内膜癌分子亚型的临床应用。方法收集中山大学附属肿瘤医院经病理确诊的子宫内膜癌112例，均进行基于1 021个基因panel的杂交捕获二代测序检测，分析各分子亚型的分子变异谱及与临床病理特征之间的关系。结果DNA聚合酶ε（POLE）突变型8例（7.1%），错配修复功能缺陷型34例（30.4%），TP53突变型26例（23.2%），非特异性分子谱型44例（39.3%），4个亚型肿瘤突变负荷中位数分别为252.0、38.4、5.8及5.4 Muts/Mb ...
刘叶 +5 more
core +1 more source
糖代谢异常与Ⅰ期子宫内膜样腺癌临床病理及预后的相关性 [PDF]
, 2021 目的探讨糖代谢异常的Ⅰ期子宫内膜样腺癌（EA）患者预后差异及其影响因素。方法选取2015年1月至2019年12月期间在中山大学孙逸仙纪念医院妇科肿瘤专科行手术治疗的Ⅰ期EA患者共387例，根据糖代谢是否正常分为糖代谢异常（IGM）组和糖耐量正常（NGT）组。其中IGM组分三个亚组，即糖尿病（DM）组、糖耐量异常（IGT）组、空腹血糖受损（IFG）组。回顾性分析各组临床病理指标及预后，探讨糖代谢异常对Ⅰ期子宫内膜样腺癌患者预后的影响及影响预后的相关因素 ...
李晶 +4 more
core +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 1, Page 7-14, January 2026.ABSTRACT Objective To perform an updated meta‐analysis evaluating the diagnostic performance of transvaginal ultrasound (TVS) for detecting lateral parametrial involvement in women with suspected deep pelvic endometriosis. Methods A literature search was performed in the Web of Science, PubMed and Scopus databases from January 2021 to May 2024 for ...
J. L. Alcázar +7 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2022 目的 分析血液学指标在子宫内膜异位症患者与子宫内膜异位症相关性卵巢癌（EAOC）患者中的差异，探讨对内异症恶变具有诊断价值的临床指标。方法 比较子宫内膜异位症患者与子宫内膜异位症相关性卵巢癌患者外周血指标（NEUT%、LYM%、MXD%、EO%、NEUT#、LYM#、MXD#、WBC、PLT、TBIL、DBIL、IBIL、ALB、CRP、CA125、HE4、NLR、MLR、PLR、ELR、CRP/ALB、SII、SIRI）的水平差异，并通过Logistic回归分析构建联合诊断指标。结果 ...
奚晓雪 +10 more
doaj
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 3, Page 372-383, March 2025.ABSTRACT Objective To assess whether premenopausal women diagnosed with deep or ovarian endometriosis on transvaginal sonography (TVS) were more likely to suffer from dyspareunia and pelvic pain symptoms, and have a lower quality of life, compared to women without sonographically diagnosed deep or ovarian endometriosis.
P. Chaggar +5 more
wiley +1 more source