Results 101 to 110 of about 905 (144)

海马干细胞来源的外泌体对血管性痴呆大鼠学习记忆能力改善作用及其机制探究 附视频

Zhongguo shiyan zhenduanxue
目的 分析海马干细胞来源的外泌体对血管性痴呆大鼠学习记忆能力改善作用及其机制。方法 取新生SD大鼠海马组织，提取海马干细胞外泌体。成年特殊清洁级(SPF)健康雄性SD大鼠90只，随机分为假手术组、模型组及外泌体组，每组30只，检测各组大鼠学习记忆能力、氧化应激因子水平、海马组织病理学变化、海马组织因子、脑微血管密度以及凋亡相关因子变化。结果 透射显微镜观察到海马干细胞来源外泌体结构呈圆形或椭圆形杯状结构的小囊泡，其结构完整，直径50～100 nm之间；特异性标记蛋白CD9、CD63表达阳性 ...
doaj   +2 more sources

[Fluoxetine enhances combined learning and memory abilities of mice by promoting neural cell functions in the barrel cortex]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2020
Zhang T, Zhang W, Sun Y, Huo Q.
europepmc   +1 more source

[Yigong San improves learning and memory functions of APP/PS1 transgenic mice by regulating brain fluid metabolism]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zeng J, Hua L, Yang Y, Zhang X, Wei J, Li L.   +5 more
europepmc   +1 more source

[<i>Lactobacillus plantarum</i> alleviates lead exposure-induced learning and memory impairment in mice by regulating bile acid metabolism and inhibiting hippocampal NLRP3 expression]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li L, Yu W, Tan M, Li Y, Liu A, Meng X.
europepmc   +1 more source

褪黑素对不同年龄SAM-P8小鼠学习记忆相关脑区的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2014
摘 要: 【目的】 研究褪黑素的短期干预对不同年龄SAM-P8脑内膈隔-海马胆碱能系统和海马结构退变的影响?【方法】 选用SAM-P8鼠36只,分为中年低?高浓度治疗组(ME1G?ME2G),老年低?高浓度治疗组(AE1G?AE2G)及其相应的对照组ACG?MCG),共6组?中年?老年治疗组分别于小鼠4月龄?7月龄时每日皮下注射褪黑素(5 mg或10 mg/kg)30 d?对照组注射相同剂量的生理盐水,给药结束后继续饲养到11月龄,采用跳台试验测试其学习及记忆能力 ...
doaj  

[Application and progress of artificial intelligence agents in drug development]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Zhao D, Hsieh C.
europepmc   +1 more source

[Drug repositioning prediction based on dynamic feature learning on heterogeneous graphs]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhu H, Guo Y, Xin X, Li C, Zhou D.
europepmc   +1 more source

[Parent-child relationship and preschoolers' social skills: the cross-time chain mediating role of executive function and emotion regulation]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Li YW, Shao YQ, Zeng QY, Tian T, Li D, Yao MM, Chi X.   +6 more
europepmc   +1 more source

[ResLSTM-TemporalSE: an automated classification model for multi-lead ECG signals]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Qu M, Fu R.
europepmc   +1 more source

[Identification of efferocytosis-related genes in osteoarthritis and prediction of traditional Chinese medicines based on bioinformatics and machine learning]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Xiang K, Zhang X, Li Z, Xu Z, Liu S, Chai Y.   +5 more
europepmc   +1 more source