Results 31 to 40 of about 905 (144)
Pharmacological Research Progress of Cistanches Herba [PDF]
目的探讨肉苁蓉药理作用。方法收集近几年国内外对肉苁蓉药理作用的研究资料,并对其进行综述。结果现代药理研究表明,肉苁蓉有润肠通便、保肝、抗骨质疏松、抗氧化、抗衰老、抗疲劳等作用。结论肉苁蓉药理作用广泛,为其临床应用提供一定的参考依据。Objective Discuss deeply the pharmacological action of cistanches herba.
方鉴
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Effects of Dendrobium nobile Lindl. alkaloids on behavior and hippocampal tissue damage in manganese-exposed rats [PDF]
BackgroundManganese is an essential trace element for the human body and maintains normal development of many organs including the brain. However, long-term exposure to a high manganese environment or excessive manganese intake will lead to manganese ...
Jida LI +8 more
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目的观察血管紧张素酶抑制剂(ACEI)类药物卡托普利对Aβ1-42诱导的阿尔茨海默痴呆模型大鼠的记忆能力,学习能力的影响以及相关机制的探究。方法把SD成年大鼠60只,随机分为,模型组和假手术组,其中模型组四个亚组各12只,假手术组12只。在各组鼠脑部两侧海马区注射Aβ1-42制作大鼠AD(Alzheimer disease)痴呆模型。假手术组,使用生理盐水注射到两侧海马区,作为对照。模型组为使用卡托普利按大、中、小剂量分三亚组和生理盐水亚组。假手术组不使用药物 ...
吴成吉 +5 more
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Research progress on the effects and mechanisms of tonifying traditional Chinese medicine ingredients in the treatment of Alzheimer's disease over the past five years [PDF]
With the intensification of population aging, the number of patients with Alzheimer's disease (AD) continues to rise. However, the exact pathogenesis of AD remains unclear, and existing drugs can only alleviate symptoms without providing a cure ...
GUO Hongwei +4 more
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Research Progress on the Effect of Synthetic Cathinones on Animal Behavior [PDF]
Synthetic cathinones are a class of new psychoactive substances with a structure similar to amphetamine drugs, which can produce excitatory effects similar to drugs such as amphetamine and cocaine after being taken.
HUANG Zhi-bin, CAI Juan, LIN Ze-bin, et al.
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目的探讨不同负荷游泳运动对大鼠学习记忆的认知能力及海马神经型一氧化氮合酶(n-NOS)表达与疲劳机制。方法将40只体重为350-400g的Wistar雄性大鼠分为对照组和每天进行15mins、30mins、60mins的小中大负荷游泳运动的实验组;实验持续8周后采用"Y迷宫"进行学习记忆能力测试;利用S-P免疫组化染色法检测海马神经n-NOS的表达水平。结果学习记忆的达标次数和错误次数,中等负荷组显著低于对照组和大负荷组 ...
刘忠民, 高喆, 牛娜, 董炜达
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生物探测器对气味具备很高的选择性和敏感性,虽然犬(Canis familiaris)一直广泛应用于各个领域,但犬在特殊场合存在局限性,需要开拓生物探测器的选择视角。介绍了犬及现有其他生物探测器的研究现状,并以松鼠(Sciurus vulgaris)作为新型生物探测器需要具备的性能角度,对松鼠的嗅觉敏感性、学习认知能力(如灵活性、持久性、短期记忆能力等)、行为特点、生活习性、社会性和可训练性等方面进行分析评估。结果表明:松鼠在嗅觉敏感性、学习认知能力、行为特点、生活习性等方面的优势明显,松鼠在社会性 ...
孙宁 1 刘慧颖 2 徐澍 1 李彪 1 彭萍 1 胡庭溪 2 尹劲 3 等
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胰岛素降低海马谷氨酸和D-丝氨酸含量改善糖尿病大鼠空间学习记忆能力 [PDF]
目的观察胰岛素对糖尿病(DM)大鼠空间学习记忆及海马组织中谷氨酸和D-丝氨酸含量的影响。方法采用尾静脉注射链脲佐菌素(STZ)制备大鼠DM模型。注射STZ第3天建模成功后,大鼠sc给予胰岛素2 U·kg-1,每天1次,持续82 d。定期检测各组大鼠体质量及空腹血糖。第81天进行Morris水迷宫实验,检测大鼠学习记忆能力;实验结束后取海马组织,观察形态变化,并测定谷氨酸和D-丝氨酸含量。结果与正常对照组比较,DM模型组大鼠体质量明显减轻 ...
宋扬 +6 more
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Study on the neurotoxic effects of different exposure durations of deltamethrin on mice’s neurobehavioral performance [PDF]
Objective To investigate the neurotoxic effects of deltamethrin (DM) on the neurobehavioral performance of mice subjected to different exposure durations.
CHEN Weiqi +6 more
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摘 要 用M orri s水迷宫行为检测方法,以青年组平均逃避潜伏期加2倍标准差为下限,加1倍标准差为 上限将老年大鼠分为学习记忆减退组和学习记忆正常组。取受试大鼠的前脑冰冻切片,行尼克酰胺腺嘌呤二核 苷酸磷酸( ni cotinamide adenine dinucleo tide ph osphat e, N ADPH)组化染色。结果显示: 37.
王怀星 姚志彬 顾耀铭 陈以慈
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