Results 111 to 120 of about 6,735 (193)
Exploring Antibacterial Effect and Mechanism of Flavonoids in Ampelopsis Based on Network Pharmacology, Molecular Docking and Experimental Verification [PDF]
To investigate the antibacterial effect and mechanism of flavonoids in Ampelopsis, network pharmacology was used to select key antibacterial flavonoid components in Ampelopsis and core targets.
ZHANG Lihui, WANG Dandan, MENG Yanlin, WANG Meihui, ZHU Xiaoyong, YAN Zhiqiang, HE Li, HUANG Wei, WANG Qiaoyan
core +1 more source
Exploring the mechanism of platycodin D in inhibiting nasopharyngeal carcinoma based on network pharmacology combined with experimental validation [PDF]
Objective To delve into the underlying mechanism of platycodin D in inhibiting nasopharyngeal carcinoma (NPC) through a combination of network pharmacology and cellular experimental techniques.
CHEN Yanfang +7 more
core +1 more source
Proteomics and Phosphoproteomics Analysis of Effect of Retinoic Acid-Induced Protein 16 Knockout on Human Colon Cancer Cells [PDF]
ObjectiveTo analyze the differences in the expressions of the total and phosphorylated proteins in human colon cancer HCT116 cells after the knockout (KO) of retinoic acid-induced protein 16 (RAI16) and explore the possible mechanism and related ...
Cuiling DING +4 more
core +1 more source
Label-Free Quantitative Comparison of N-Glycoproteomics between Camel and Cow Milk [PDF]
To understand the differential N-glycoprotein characteristics of camel versus cow milk, we employed label-free quantitative N-glycoproteomics to compare the N-glycoprotein composition and the number of N-glycosylation sites between the two milks and ...
LI Danlei, KONG Xiabing, YU Yue, HU Qian, ZHANG Jiukai, CHEN Ying
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Shuitu Baochi Xuebao, 2018 利用钻探和抽水试验资料，结合遥感资料和植被实地样方调查资料，分析了该区地下水富集特征和开发利用对生态环境的影响。结果表明：含水层的厚度是地下水富集的主控因素，二者呈正相关关系；基底古凹陷分布区含水层厚度较大，是地下水的富集区；埋深3 m是滩地地下水开采的约束水位，过量的开采可能造成湖盆滩地植被向沙地植被的演替或退化，甚至消亡，加快沙漠化进程；地下水开采对沙地、沙丘生长的耐干旱植被物种的影响较小。研究结果可为该区内水源地选址、地下水合理开发利用、水土保持和生态环境保护提供基础理论和数据。
范磊, 侯光才, 陶正平
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Analysis of the venom components of necrotic tissue exudates from Naja atra venom-infected Guangxi Bama miniature pigs [PDF]
Objective To investigate the components of snake venom and the dynamic changes in protein expression in the exudates of necrotic tissues affected by the Naja atra venom in Guangxi Bama miniature pigs.
GUAN Zhezhe +7 more
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 1996 用Ｇｅｎｅｐｒｏ程序在计算机上对抗肌萎缩蛋白基因缺失热区部分４４号、５０号和５１号内含子进行分析，结果表明该基因缺失热区ＡＴ（腺嘌呤－胸腺嘧啶）含量高，呈聚集性分布。并存在多个同源顺序。该结果支持作者以前提出的“不同内含子中ＡＴ富集区的同源顺序与ＤＮＡ缺失有关”的结论。
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Zhongguo shiyan zhenduanxue, 2012 北沙参为常用中药,2010版《中华人民共和国药典》收载为伞形科植物珊瑚菜Glehnia littoralisFr.Schmidt ex Miq.的干燥根,其化学成分丰富,类型复杂,具有镇咳祛痰、抗菌、抗癌和滋阴补虚等药理作用。目前对北沙参的相关研究主要集中在栽培种植技术和化学成分鉴定分离分析等方面,
李建业 +4 more
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Zhongshan Daxue xuebao. Yixue kexue ban目的探讨NR2F1分子介导的休眠卵巢癌（OC）细胞对化疗药物耐药的分子机制。方法利用GEPIA数据库分析OC患者中NR2F1分子的表达及其与患者总生存期的关系；采用慢病毒体外转染构建核受体亚家族2组F1（NR2F1）过表达的OC细胞株和对照细胞； CCK-8试剂盒检测OC细胞的增殖；实时荧光定量PCR（qRT-PCR）分析OC细胞中休眠相关分子基因mRNA的表达水平；蛋白质免疫印迹试验分析相关分子蛋白表达水平；台盼蓝排除法分析不同化疗药物作用下OC细胞的活力；Annexin V-FITC ...
郭宁, 居颂文
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