Results 101 to 110 of about 6,153 (166)

Nestin-GFP小鼠胚胎干细胞的建系及体外神经分化

Zhongshan Daxue xuebao. Yixue kexue ban, 2011
【目的】 建立Nestin-GFP转基因小鼠的胚胎干细胞(mESC)系，并观察其示踪ES细胞系的神经分化过程【方法】将E3.5的Nestin-GFP小鼠囊胚接种于小鼠胚胎成纤维细胞上(MEF经γ射线照射失去增殖活性)4 ~ 6 d后将自囊胚长出的内细胞团(ICM)继续培养并传代扩增 ，检测所得细胞Oct-4SSEA-1和AKP等胚胎干细胞特异性标志物的表达及在体内外向三胚层分化的能力；之后，诱导细胞向神经元样细胞及神经胶质样细胞分化，利用免疫荧光检测其标志性抗原【结果】 免疫组化可见Nestin ...
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[Kahweol improves motor function of mice with spinal cord injury by inhibiting microglial activation <i>via</i> regulating the IκBα/NF-κB pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Xia J, Chen Y, Ren L, Li J, Song X, Tao L, Hu J.   +6 more
europepmc   +1 more source

EGR2 maintains neuropathic pain by promoting microglial phagocytosis. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Xi C, Zhang J, Huang Z, He L, Zou K, Xu X, Guo Q, Sun B, Huang C.   +8 more
europepmc   +1 more source

[Effect of removing microglia from spinal cord on nerve repair after spinal cord injury in mice]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Jiang Q, Qi C, Sun Y, Xue S, Wei X, Fu H.   +5 more
europepmc   +1 more source

[Hypericin ameliorates stress-induced depressive-like behaviors in mice by modulating the CN-NFAT calcium signaling pathway in microglia]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Gao Z, Lin P, Zhou B, Chen M, Liu E, Lei T, Ni H, Liu H, Lin Y, Xu Q.   +9 more
europepmc   +1 more source

紫云英苷调控炎性痛模型小鼠L_4-5脊髓背角星形胶质细胞自噬与凋亡

Zhongshan Daxue xuebao. Yixue kexue ban
目的探究紫云英苷（AST）对完全弗氏佐剂（CFA）诱发的炎性痛小鼠L4-5脊髓背角星形胶质细胞自噬及凋亡的影响。方法将24只雄性6月龄C57BL/6小鼠随机分为正常组（control）、生理盐水组（saline）、CFA模型组、CFA+AST组，每组6只小鼠。于小鼠右侧腓骨外踝窝注射10 µL CFA建立炎性痛小鼠模型。saline组小鼠注射等量生理盐水。CFA+AST组小鼠在疼痛造模成功后腹腔注射给药60 mg/kg AST，每日一次，连续给药21 d。采用多重免疫荧光染色法检测各组小鼠L4 ...
张维珊, 林佳泓, 王灿, 张润恒, 杨俊华, 刘靖, 李国营, 马宇昕   +7 more
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[Impact of chaperone-mediated autophagy on bilirubin-induced damage of mouse microglial cells]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Pan ZF, Li SY, Li L, Zhang Y, Hua ZY.
europepmc   +1 more source

[Gastrodin alleviates microglia-mediated inflammatory responses in neonatal mice with hypoxic-ischemic brain damage by regulating CCR5/AKT signaling]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Shi J, Zhang H, Zhang X, Shi H, Zuo H, Guo T, Wang Z, Yu H, Li J.   +8 more
europepmc   +1 more source

[Gastrodin improves microglia-mediated inflammatory response after hypoxic-ischemic brain damage in neonatal rats via PI3K/AKT pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zuo H, Duan Z, Wang Z, Guo T, Shi J, Shi H, Li J.   +6 more
europepmc   +1 more source

[Experimental study of M2 microglia transplantation promoting spinal cord injury repair in mice]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhang J, Zhang X, Jiang Q, Qu D, Hu Y, Qi C, Fu H.   +6 more
europepmc   +1 more source