[Overwork damages myocardial energy metabolism homeostasis in mice]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoCui J +6 more
europepmc +1 more source
ＨＬＡ－Ａ*０２０１转基因小鼠侵袭性肺曲霉病模型的建立与鉴定
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 摘 要： 【目的】 建立ＨＬＡ－Ａ*０２０１转基因小鼠侵袭性肺曲霉病模型，并进行实验室鉴定。【方法】 在真菌孢子感染前，给予ＨＬＡ－Ａ*０２０１转基因小鼠腹腔注射环磷酰胺。乙醚麻醉后，小鼠经鼻腔吸入３组不同浓度的（３ × １０６、３ × １０７、３ × １０８ ｍＬ－１）烟曲霉孢子悬液。阴性对照组小鼠吸入ＰＢＳ。感染后３６ ｈ，处死各组小鼠，取肺组织病理行ＨＥ、ＰＡＳ以及ＧＭＳ染色分析，以验证感染是否成功并计算肺侵袭性肺烟曲霉感染小鼠模型成模率。肺组织研磨涂皿后行菌落计数，分析小鼠肺烟曲霉负载量。【结果】
doaj
[Establishment of a chronic lymphocytic leukemia mouse model via adoptive transfer of Eμ-TCL1 transgenic splenocytes]. [PDF]
Zhonghua Xue Ye Xue Za ZhiZhang MX +8 more
europepmc +1 more source
[Characterization of the Effect of Tongue on Palatal Shelf Elevation Patterns in a Mouse Model of Palatogenesis]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanZhang Y, Yang H, Zhang D, Li D, Wang X.
europepmc +1 more source
[Development and electrophysiological validation of a temporal interference transcranial magnetic stimulation system for mice]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za ZhiCui C, Wang T, Zhang Y, Zheng W, Xu G.
europepmc +1 more source
大麻素1型受体在实验性自身免疫性脑脊髓炎小鼠中的 动态表达及其作用
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 摘 要: 【目的】 观察大麻素1型受体(CB1R)在C57B/L6小鼠神经元和胶质细胞的表达及其在实验性自身免疫性脑脊髓炎(EAE)小鼠中枢神经系统(CNS)和外周免疫器官的动态变化及其作用?【方法】 取C57B/L6胎鼠的海马培养神经元及新生C57B/L6新生小鼠的皮层培养星形胶质细胞和小胶质细胞, 观察CB1R蛋白的表达;观察正常对照?完全弗氏佐剂?EAE 和特异性CB1R抑制剂(SR141716A,SR1)干预组小鼠的神经功能缺损症状和体质量变化;用real time PCR检测CB1R ...
doaj
[Temporal changes of chronic postsurgical pain in mice: the regulatory role of CX3CL1 in the dorsal root ganglion]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhao B +8 more
europepmc +1 more source
Kir6.1基因敲除小鼠脑梗死周围扩散性去极化波的 内源光信号成像
Zhongshan Daxue xuebao. Yixue kexue ban, 2015 【目的】 观测小鼠脑梗死周围扩散性去极化波(PID)的内源光信号变化特征,了解Kir6.1基因敲除对小鼠PID的影响?【方法】 以Kir6.1基因敲除小鼠及同窝野生型小鼠各10只为研究对象,线栓法制备大脑中动脉梗死(MCAO)模型,应用四波长内源光信号(OIS)成像技术监测PID的发作情况,比较两组之间的差异?【结果】 OIS成像显示PID在空间分布上表现为由发源处向四周缓慢播散的?红蓝相间的弧形波,;PID存在4种不同播散类型:喙-尾播散类型?侧方-内侧播散类型?尾-喙播散类型和对侧播散类型;Kir6.
doaj
[Acupuncture alleviates chronic airway inflammation in obese asthmatic mice by downregulating Vnn1 and FAM126B]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLi X, Ye T, Xi L, Li C, Liu H.
europepmc +1 more source
[Effects and Mechanisms of Yangyin Yiqi Huoxue Formula on the Oral Microecology in Sjögren's Syndrome Model Mice]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanWu F +6 more
europepmc +1 more source