Results 1 to 10 of about 2,198 (117)
高脂饮食诱导
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的探讨高脂饮食引起的慢性炎症反应与阿尔兹海默病神经功能障碍之间的关系。方法12月龄C57BL/6J小鼠和APPswe/PS1ΔE9（APP/PS1）雄性小鼠，按体质量随机分为4组，正常组（C57BL/6J小鼠n=6）、普通高脂组（C57BL/6J小鼠+高脂饲料n=6）、痴呆组（APP/PS1小鼠n=6）、痴呆高脂组（APP/PS1小鼠+高脂饲料n=6）4组；普通饲料/高脂饲料喂养6周。每周监测小鼠体质量变化，免疫组化观察海马小胶质细胞激活情况，RT-qPCR检测海马炎性因子IL-1β、IL-6、TNF-
李泽 +6 more
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四神聪电针预防急性睡眠剥夺大鼠海马神经元凋亡的机制及对焦虑行为的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2022 目的探讨四神聪电针预防急性睡眠剥夺大鼠海马神经元凋亡的机制及对焦虑行为的影响。方法将SD大鼠随机分为Sham组（对照组）、sleep deprivation（SD，睡眠剥夺组）、EA+SD组（eletroacupuncture，电针干预组）。采用改良水平台法对SD组、EA+SD组进行连续4天的急性睡眠剥夺，电针组在睡眠剥夺期间于四神聪穴位进行电针治疗，连续4 d，每天20 min。采用旷场实验检测大鼠探索能力以评估大鼠焦虑程度，并通过免疫荧光染色检测海马中CA1、CA2、CA3、DG1 ...
焦博钰 +5 more
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Integrative Conservation, Volume 5, Issue 2, Page 225-235, June 2026.This study used camera trap data from 6 years between 2016 and 2021 and generalized linear mixed models to explore the factors that influence the spatial density distribution of lynx and its prey populations in warm and cold seasons in Inner Mongolia Hanma National Nature Reserve, China.
Wentao Zhang +11 more
wiley +1 more source
Integrative Conservation, Volume 5, Issue 2, Page 177-191, June 2026.A survey of IUCN Bear Specialist Group (BSG) members revealed that habitat loss, degradation and fragmentation is the greatest threat to each of the 7 species of terrestrial bears. Poaching and human–bear conflicts are also high threats for some of these species.
David L. Garshelis +3 more
wiley +1 more source
Harnessing social media data to track species range shifts
Conservation Biology, Volume 40, Issue 3, June 2026.Abstract Biodiversity monitoring programs and citizen science data remain heavily biased toward the Global North. Especially in megadiverse countries with limited biodiversity records, incorporating social media data can help address existing data gaps.
Shawan Chowdhury +15 more
wiley +1 more source
Conservation Biology, Volume 40, Issue 2, April 2026.Abstract Measuring area‐based conservation outcomes in tropical forests is challenging due to cryptic human disturbances (e.g., hunting). As a result, comparative studies of management strategies providing quantitative outcomes remain scarce, especially in the Neotropics.
Lucy Perera‐Romero +5 more
wiley +1 more source
Integrative Conservation, Volume 5, Issue 1, Page 125-136, March 2026.We collated detections of the sun bear from new and previously published camera trap studies across its range. We then analysed these detections at two different spatial scales to assess the habitat associations and diel activity of this species. We found that the sun bear is tolerant to moderate habitat disturbances. ABSTRACT Degraded tropical forests,
Alexander Hendry +5 more
wiley +1 more source
实验性阿尔茨海默模型大鼠海马内病理和PCNAmRNA表达的变化及rLent/NT4-NAP对其的影响
Zhongguo shiyan zhenduanxue, 2011 目的探讨实验性阿尔茨海默病模型大鼠脑内海马光镜下的变化和DNA修复蛋白PCNAmRNA表达的变化,进一步探讨神经保护肽慢病毒rLent/NT4-NAP（NAP）对其具有神经保护作用机制。方法选择无菌级雄性大鼠Wister大鼠40只,随机分为对照组,假手术组,阿尔茨海默（AD）模型大鼠组,rLent/NT4-NAP（NAP）组,每组10只。建立Aβ1-40联合应用转移生长因子β1（TGFβ1）注入实验大鼠左侧海马区制备阿尔茨海默动物模型,通过HE染色观察各组大鼠海马区的形态学改变 ...
白晶, 房绍宽, 张影, 周春奎
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Integrative Conservation, Volume 5, Issue 1, Page 74-85, March 2026.This study investigates distribution patterns of Galliforms in the Indian Himalayas, focusing on factors influencing their occurrence, regions of high diversity and endemism, and their overlap with protected areas. Our study highlights the need for assemblage‐level conservation strategies in high Himalaya which primarily relies on snow leopard‐focused ...
Manvi Sharma +5 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2007 [目的]通过观察快速衰老小鼠（SAM）在衰老过程中海马中nNOS的分布和表达变化,探讨NO/nNOS在中枢神经系统衰老中的作用。[方法]采用雄性快速衰老亚系8小鼠（SAMP8）及抗快速衰老亚系1小鼠（SAMR1）为研究对象,其中SAMP8为实验组,SAMR1为对照组,每组动物再分为青年组（2月龄）和老年组（10月龄）两组,每个年龄组随机分配6只动物。用免疫组织化学法标记SAM海马中nNOS神经元,观察海马CA1,CA2和CA3区nNOS神经元的形态和分布,并计数nNOS神经元的数量;用RT ...
张立红 +4 more
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