Results 1 to 10 of about 326,026 (161)
神经元型一氧化氮合酶在快速衰老小鼠海马中的增龄性改变 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2007 [目的]通过观察快速衰老小鼠（SAM）在衰老过程中海马中nNOS的分布和表达变化,探讨NO/nNOS在中枢神经系统衰老中的作用。[方法]采用雄性快速衰老亚系8小鼠（SAMP8）及抗快速衰老亚系1小鼠（SAMR1）为研究对象,其中SAMP8为实验组,SAMR1为对照组,每组动物再分为青年组（2月龄）和老年组（10月龄）两组,每个年龄组随机分配6只动物。用免疫组织化学法标记SAM海马中nNOS神经元,观察海马CA1,CA2和CA3区nNOS神经元的形态和分布,并计数nNOS神经元的数量;用RT ...
张立红 +4 more
doaj +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2020 【目的】探讨口服益生菌能否改善铝暴露诱发的小鼠海马炎症。【方法】通过给予小鼠口服氯化铝，建立海马炎症模型，将24只8周龄雄性小鼠C57BL/6随机分成对照（CON）组、氯化铝处理（Al）组、益生菌处理（PO）组和联合处理（Al+PO）组，每组各6只，分别持续给予口服氯化铝和（或）益生菌6周。海马神经炎症的评估，采用免疫荧光染色法检测小鼠海马组织中激活的小胶质细胞（Iba-1+/CD68+）数量以及脑源性神经营养因子（BDNF）的表达量，酶联免疫吸附测定法检测血清和海马组织中白介素-1β（IL-1β ...
袁丽芳 +5 more
doaj +1 more source
Review on Non-targeted Detection Technique for Food Safety and Quality(食品非目标性检测技术) [PDF]
Shipin kexue jishu xuebao, 2016 Non-targeted detection technique has been extensively applied in the food safety and quality in recent years. In general, a non-targeted detection combines analytical approaches,fingerprinting techniques and chemometrics to detect toxicants or foreign ...
Liangli (Lucy) Yu(俞良莉) +3 more
doaj +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】探讨海马养生液延缓衰老的作用。【方法】采用果蝇生存实验及大鼠抗氧化作用实验方法。果蝇喂饲分量的质量分数为 0. 78%, 2. 33%, 7%, 14%; 老龄大鼠实验剂量为 0. 58 g/kg, 1. 17 g/kg, 3. 50 g/kg。【结果】海马养生液能明显延长果蝇的平均寿命和平均最 高寿命,降低受试大鼠血清中过氧化脂质降解产物丙二醛(MDA)含量,增高血清中超氧化物歧化酶( SOD)活力。【结论】海马养生液具有延缓 衰老的作用。
李文立, 黄俊明, 陈壁锋
doaj +1 more source
Review of Sn-2 Palmitate Implications for Infant Health(Sn-2棕榈酸酯对婴幼儿健康的促进作用) [PDF]
Shipin kexue jishu xuebao, 2018 Human milk provides the optional balanced nutrition for the growing infant after birth. In recent years, researchers are gradually aware that the specific esterification position of palmitic acid in human milk (about 70% of palmitic acid esterificated in
YANG Puyu(杨普煜) +6 more
doaj +1 more source
高脂饮食诱导
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的探讨高脂饮食引起的慢性炎症反应与阿尔兹海默病神经功能障碍之间的关系。方法12月龄C57BL/6J小鼠和APPswe/PS1ΔE9（APP/PS1）雄性小鼠，按体质量随机分为4组，正常组（C57BL/6J小鼠n=6）、普通高脂组（C57BL/6J小鼠+高脂饲料n=6）、痴呆组（APP/PS1小鼠n=6）、痴呆高脂组（APP/PS1小鼠+高脂饲料n=6）4组；普通饲料/高脂饲料喂养6周。每周监测小鼠体质量变化，免疫组化观察海马小胶质细胞激活情况，RT-qPCR检测海马炎性因子IL-1β、IL-6、TNF-
李泽 +6 more
doaj
鱼藤酮对大鼠认知功能及其海马Warburg效应和小胶质细胞极化的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的探究鱼藤酮（ROT）对大鼠认知功能及其海马Warburg效应和小胶质细胞极化的影响。方法雄性SD大鼠随机分为对照组和ROT处理组。ROT处理组大鼠颈背部皮下注射ROT（2 mg/kg），对照组注射等量的溶剂。Y迷宫实验和新物体识别实验评估大鼠的认知功能，Western blot检测海马Warburg效应相关蛋白己糖激酶2（HK2）、丙酮酸激酶同工酶2（PKM2）、丙酮酸脱氢酶激酶1（PDK-1）、丙酮酸脱氢酶（PDH）、乳酸脱氢酶A（LDHA）和小胶质细胞极化标志性蛋白诱导型一氧化氮合成酶（iNOS）
胡宇 +5 more
doaj
电针对SNI诱导疼痛抑郁模型大鼠海马AcH3/BDNF的影响 [PDF]
, 2023 目的观察电针对疼痛抑郁模型大鼠海马脑源性神经营养因子（BDNF）、乙酰化蛋白（AcH3）表达的影响，探讨电针镇痛抗抑郁的作用机制。方法雄性SD大鼠随机分为假手术组、模型组、电针组、药物组，每组6只。采用坐骨神经选择损伤术（SNI）建立疼痛抑郁模型。SNI术后1周进行相关干预直至术后6 周，电针组于隔日电针百会、印堂2 Hz 30 min治疗；药物组给予每日10 mg/kg丙咪嗪腹腔注射；假手术组、模型组给予相同的抓取。术前及术后1、2、3、4、5、6 周进行机械缩足反射阈值（PWT）测试 ...
马瑞 +6 more
core +1 more source
Tracing change in the public perception of plants: insights from archives and social media in China
PLANTS, PEOPLE, PLANET, EarlyView.As urbanization accelerates, historic gardens serve as vital cultural treasures that offer spiritual and cultural support to the public. This study proposes an innovative approach that merges historical records from the Qing Dynasty with contemporary social media data to explore changes in public perceptions of these gardens.
Dong Xu +4 more
wiley +1 more source
Using customs data to understand overlooked trade in non‐CITES birds between Africa and Asia
Conservation Biology, EarlyView.Abstract The international trade in live birds poses risks to animals, people, and biodiversity. To effectively mitigate these risks, decision‐makers require information on the volume, dynamics, and direction of trade. Despite Africa once being the largest exporter of birds by region, very little data exist on recent trade in live birds not listed on ...
Alisa Davies +4 more
wiley +1 more source