Results 11 to 20 of about 3,483 (117)

鱼藤酮对大鼠认知功能及其海马Warburg效应和小胶质细胞极化的影响

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2021
目的探究鱼藤酮(ROT)对大鼠认知功能及其海马Warburg效应和小胶质细胞极化的影响。方法雄性SD大鼠随机分为对照组和ROT处理组。ROT处理组大鼠颈背部皮下注射ROT(2 mg/kg),对照组注射等量的溶剂。Y迷宫实验和新物体识别实验评估大鼠的认知功能,Western blot检测海马Warburg效应相关蛋白己糖激酶2(HK2)、丙酮酸激酶同工酶2(PKM2)、丙酮酸脱氢酶激酶1(PDK-1)、丙酮酸脱氢酶(PDH)、乳酸脱氢酶A(LDHA)和小胶质细胞极化标志性蛋白诱导型一氧化氮合成酶(iNOS)
胡宇   +5 more
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口服益生菌改善铝诱发的小鼠海马炎症

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2020
【目的】探讨口服益生菌能否改善铝暴露诱发的小鼠海马炎症。【方法】通过给予小鼠口服氯化铝,建立海马炎症模型,将24只8周龄雄性小鼠C57BL/6随机分成对照(CON)组、氯化铝处理(Al)组、益生菌处理(PO)组和联合处理(Al+PO)组,每组各6只,分别持续给予口服氯化铝和(或)益生菌6周。海马神经炎症的评估,采用免疫荧光染色法检测小鼠海马组织中激活的小胶质细胞(Iba-1+/CD68+)数量以及脑源性神经营养因子(BDNF)的表达量,酶联免疫吸附测定法检测血清和海马组织中白介素-1β(IL-1β ...
袁丽芳   +5 more
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Using customs data to understand overlooked trade in non‐CITES birds between Africa and Asia

open access: yesConservation Biology, Volume 40, Issue 4, August 2026.
Abstract The international trade in live birds poses risks to animals, people, and biodiversity. To effectively mitigate these risks, decision‐makers require information on the volume, dynamics, and direction of trade. Despite Africa once being the largest exporter of birds by region, very little data exist on recent trade in live birds not listed on ...
Alisa Davies   +4 more
wiley   +1 more source

Seasonal Spatial Population Density Distribution Dynamics of Lynx and Ungulate Prey in Cold‐Temperate Coniferous Forests 寒温带针叶林猞猁和有蹄类猎物种群密度空间分布的季节性动态研究

open access: yesIntegrative Conservation, Volume 5, Issue 2, Page 225-235, June 2026.
This study used camera trap data from 6 years between 2016 and 2021 and generalized linear mixed models to explore the factors that influence the spatial density distribution of lynx and its prey populations in warm and cold seasons in Inner Mongolia Hanma National Nature Reserve, China.
Wentao Zhang   +11 more
wiley   +1 more source

Threats to the World's Bears and Efforts to Conserve Them: Perspectives and Actions of IUCN Bear Specialist Group Members 世界熊类面临的威胁及其保护努力:IUCN熊类专家组成员的观点与行动

open access: yesIntegrative Conservation, Volume 5, Issue 2, Page 177-191, June 2026.
A survey of IUCN Bear Specialist Group (BSG) members revealed that habitat loss, degradation and fragmentation is the greatest threat to each of the 7 species of terrestrial bears. Poaching and human–bear conflicts are also high threats for some of these species.
David L. Garshelis   +3 more
wiley   +1 more source

Harnessing social media data to track species range shifts

open access: yesConservation Biology, Volume 40, Issue 3, June 2026.
Abstract Biodiversity monitoring programs and citizen science data remain heavily biased toward the Global North. Especially in megadiverse countries with limited biodiversity records, incorporating social media data can help address existing data gaps.
Shawan Chowdhury   +15 more
wiley   +1 more source

Policy, Waste, and Power: Textile Dumping in Chile's Atacama Desert

open access: yesLatin American Policy, Volume 17, Issue 2, June 2026.
ABSTRACT Globally, 87% of textile fibers end up incinerated or in landfills, with Chile bearing the brunt of this crisis. Every year, 39,000 tons of discarded clothing are illegally dumped in the Atacama Desert, turning it into a sacrifice zone for the Global North's waste economy.
Emma Minerva Brambilla
wiley   +1 more source

海洛因及补偿AMP和GMP对大鼠海马组织腺苷脱氨酶的影响

open access: yesZhongguo shiyan zhenduanxue, 2010
目的探讨海洛因及补偿AMP和GMP对海马组织嘌呤核苷酸分解代谢关键酶ADA的影响。方法剂量递增腹腔注射海洛因及嘌呤核苷酸,建立了海洛因及补偿AMP和GMP的给药与依赖大鼠模型,用试剂盒检测海马组织腺苷脱氨酶(ADA)的活性。提取海马组织总RNA,采用逆转录聚合酶链反应检测海马组织ADA mRNA的水平,以β-actin mRNA为内标。结果海马组织中ADA含量测定结果显示,与盐水对照组相比,核苷酸组和海洛因组的海马组织ADA含量明显升高 ...
阚慕洁, 付海英, 洪敏, 刘畅
doaj  

Use of species’ responses to cryptic anthropogenic disturbances for monitoring biodiversity outcomes in tropical forests

open access: yesConservation Biology, Volume 40, Issue 2, April 2026.
Abstract Measuring area‐based conservation outcomes in tropical forests is challenging due to cryptic human disturbances (e.g., hunting). As a result, comparative studies of management strategies providing quantitative outcomes remain scarce, especially in the Neotropics.
Lucy Perera‐Romero   +5 more
wiley   +1 more source

兴奋毒损伤海马神经细胞机制的研究

open access: yesZhongguo shiyan zhenduanxue, 2003
目的 探讨谷氨酸 (Glutamicacid ,Glu)的神经性兴奋毒损伤作用机制。方法 在体外快速剥离新生大鼠 (0 1天 )双侧海马 ,制成海马神经细胞悬液 ,用Fura 2 /AM负载 ,建立了Fura 2 /AM检测海马神经细胞胞内游离钙离子浓度 ([Ca2 + ]i)的方法 ,并检测Glu兴奋毒对海马神经细胞 [Ca2 + ]i的影响。结果 Fura 2单细胞检测表明 ,静息状态下海马神经细胞 [Ca2 + ]i=2 5 2 .6± 36 .1(nmol/L) ,Glu可使海马神经细胞 ...
咸云淑, 熊文, 程刚
doaj  

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