Results 21 to 30 of about 2,294 (165)

Effects of Different Concentrations of Alcohol On Spatial Learning and Memory Ability and Hippocampal GFAP/NEUN in Mice [PDF]

open access: yes, 2017
目的 探究长期饮酒对小鼠行为学能力以及空间学习记忆能力的影响。方法 雄性KM小鼠45只,随机分成对照组(Con),低剂量组(Low)和高剂量组(High)。分别每天对照组0.10 ml/10 g自来水,低剂量组0.05 ml/10 g的56度红星二锅头,高剂量组0.10 ml/10 g的56度红星二锅头进行灌胃。连续灌胃13 d后进行衣架实验测行为学能力,最后取海马做免疫荧光染色观察海马神经元和星形胶质细胞。结果衣架实验得分,自主活动数值总体显示Low组高于其他两组,而且与Con组差异显著 ...
夏天   +7 more
core   +1 more source

Using customs data to understand overlooked trade in non‐CITES birds between Africa and Asia

open access: yesConservation Biology, EarlyView.
Abstract The international trade in live birds poses risks to animals, people, and biodiversity. To effectively mitigate these risks, decision‐makers require information on the volume, dynamics, and direction of trade. Despite Africa once being the largest exporter of birds by region, very little data exist on recent trade in live birds not listed on ...
Alisa Davies   +4 more
wiley   +1 more source

The Role of BIN1 in Alzheimer’s Disease [PDF]

open access: yes, 2015
阿尔茨海默症(Alzheimer’sdisease,AD)是与年龄相关的神经退行性疾病,其主要的病理学特征为由β-淀粉样蛋白(-amyloid,Aβ)聚集产生的老年斑(senileplaues,SP)以及由异常磷酸化的tau蛋白组成的神经纤维缠结(neurofibrillarytangles,NFTs)。Aβ是由淀粉样前体蛋白(-amyloidprecursorprotein,APP)经过β-分泌酶和γ-分泌酶的依次顺序剪切而产生 ...
牛萌萌
core  

Use of species’ responses to cryptic anthropogenic disturbances for monitoring biodiversity outcomes in tropical forests

open access: yesConservation Biology, Volume 40, Issue 2, April 2026.
Abstract Measuring area‐based conservation outcomes in tropical forests is challenging due to cryptic human disturbances (e.g., hunting). As a result, comparative studies of management strategies providing quantitative outcomes remain scarce, especially in the Neotropics.
Lucy Perera‐Romero   +5 more
wiley   +1 more source

The neuronal cell cycle regulation mechanism and related animal model in Alzheimer’s disease [PDF]

open access: yes, 2015
阿尔茨海默病(Alzheimer’sDisease,AD)是一种与年龄相关的神经退行性疾病,它的主要临床表现是记忆和认知功能的逐渐衰退。AD是一种严重影响人类健康的神经退行性疾病,至今仍未找到有效的治疗方法。因此从预防和早期治疗角度考虑,对于AD早期病理变化的研究就十分重要。成熟神经元处于细胞周期静止期,而在AD中,大量神经元的细胞周期被重新激活,但这些神经元不会再分裂而是最终走向了凋亡,这是目前在AD小鼠模型中已知最早的细胞功能紊乱。但对细胞周期重新激活导致神经元凋亡的机制目前还不清楚 ...
李小萍
core  

Sun Bear Ecology and Conservation: Multiscale Habitat Associations in Southeast Asia 马来熊的生态与保护:东南亚地区的多尺度生境关联研究

open access: yesIntegrative Conservation, Volume 5, Issue 1, Page 125-136, March 2026.
We collated detections of the sun bear from new and previously published camera trap studies across its range. We then analysed these detections at two different spatial scales to assess the habitat associations and diel activity of this species. We found that the sun bear is tolerant to moderate habitat disturbances. ABSTRACT Degraded tropical forests,
Alexander Hendry   +5 more
wiley   +1 more source

A MRI study of white matter changes in mesial temporal lobe epilepsy patients [PDF]

open access: yes, 2015
目的 运用基于体素的形态学测量(voxel-basedmorphometry,VBM)及基于纤维束骨架的空间统计方法(tract-basedspatialstatistics,TBSS)对内侧颞叶癫痫(mesialtemporallobeepilepsy,MTLE)患者全脑白质体积和白质纤维束弥散张量成像(diffusiontensorimaging,DTI)参数进行分析,并探讨MTLE患者脑白质结构改变与认知水平的关系。 材料和方法 选取24例右利手MTLE患者,其中左侧MTLE12例 ...
席继辉
core  

Are Galliformes of the High Himalayas Well Protected? Identifying Conservation Priority Areas Using an Assemblage‐Level Approach 高喜马拉雅地区的鸡形目鸟类是否得到了有效保护?利用群落水平方法确定优先保护区域

open access: yesIntegrative Conservation, Volume 5, Issue 1, Page 74-85, March 2026.
This study investigates distribution patterns of Galliforms in the Indian Himalayas, focusing on factors influencing their occurrence, regions of high diversity and endemism, and their overlap with protected areas. Our study highlights the need for assemblage‐level conservation strategies in high Himalaya which primarily relies on snow leopard‐focused ...
Manvi Sharma   +5 more
wiley   +1 more source

The effect of overexpressing SNX8 on the phenotype of Alzheimer’s mice [PDF]

open access: yes, 2015
阿尔茨海默病(Alzheimerdisease,AD)是最为常见的神经退行性疾病。神经元胞外Aβ(Amyloidβ,Aβ)聚集形成的淀粉样斑是AD的一个重要的病理特征,而Aβ是由淀粉样前体蛋白APP(AmyloidPrecursorProtein,APP)经β-分泌酶(β-secretase)和γ-分泌酶(γ-secretase)依次切割后生成的(即淀粉样蛋白途径),而APP的另一条剪切途径是α-分泌酶(α-secretase)和γ-分泌酶依次对其进行剪切,释放有神经保护作用的sAPPα ...
纪成香
core  

CHINA’S LAND FINANCE AS ACTIVE MODE OF LAND DEVELOPMENT AND INFRASTRUCTURE DELIVERY: Reality, History and Prospects

open access: yesInternational Journal of Urban and Regional Research, Volume 50, Issue 1, Page 191-220, January 2026.
Abstract Henry George advocated for capturing land value increases for public ends. The active approach of public authorities organizing and financing land development can help capture higher land value increases, as Hartman and Spit indicate. However, this approach hardly happens in developing countries, where the coalition of private developers and ...
Nannan Xu
wiley   +1 more source

Home - About - Disclaimer - Privacy