Results 71 to 80 of about 1,777 (140)
Research Progress on Mechanism of NAD+ Metabolic Remodeling in Occurrence and Development of Glioblastoma Multiforme [PDF]
Gliomas, especially high-grade gliomas such as glioblastoma multiforme (GBM), are primary malignant tumors of the central nervous system, characterized by high proliferative capacity, invasiveness, and therapeutic resistance.
Chengwen WANG +6 more
core +1 more source
Biological activity and food application of carboxymethyl pachymaran [PDF]
Carboxymethyl pachymaran （CMP） is a carboxymethylated modification product of the water-insoluble polysaccharides from Poria cocos. It has many biological activities such as immune regulation, antibacterial, anti-inflammatory, anti-tumor, anti-oxidation,
DAI Xinwen +4 more
core +1 more source
Research progress of the immunosuppressive tumor microenvironment in multiple myeloma [PDF]
Multiple myeloma (MM) is a hematological malignancy originating from the immune system, and the immune microenvironment plays a pivotal role in its pathogenesis and progression.
Peng LIU, Yue WANG
core +1 more source
[Regulatory mechanism of deferoxamine on macrophage polarization and wound healing in mice with deep tissue injury]. [PDF]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi, 2022 Shan H +4 more
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban巨噬细胞作为心脏固有免疫系统的关键细胞，具有高度异质性和可塑性，在心脏生理和病理进程中发挥双重作用。近年，巨噬细胞源性外泌体作为细胞间通讯的重要介质，在心脏疾病中的调控机制及潜在治疗应用备受关注。本文系统总结心脏常驻巨噬细胞的起源、分布和功能，探讨M1和M2型巨噬细胞在心脏炎症反应和组织修复中的作用，以及巨噬细胞外泌体在心脏疾病中的调控机制和治疗应用前景。在心脏损伤急性阶段，M1型巨噬细胞通过分泌促炎细胞因子等引发炎症，清除细胞碎片，但过度激活会导致心肌细胞损伤和纤维化；恢复阶段，M2型巨噬细胞主导 ...
谭云科, 杨正飞
doaj
Research progress on the effect of type 2 diabetes and hypoglycemic drugs on the prognosis of patients with colorectal cancer [PDF]
In recent years，the comorbidity of CRC and DM has become more and more common，and has become one of the public health problems that seriously endanger human health.
ZHANG Meng，LEI Xuefen，CHEN Haixia，CHEN Yixuan，JIANG Li
core +2 more sources
Zhongshan Daxue xuebao. Yixue kexue ban目的探讨广州管圆线虫来源的Acan-Gal-1调控巨噬细胞免疫表型和Annexin A2/S100A10膜表面易位的分子机制。方法采用IFA方法检测巨噬细胞中Annexin A2和S100A10的定位；采用流式细胞术和ELISA检测巨噬细胞功能变化；通过siRNA干扰Annexin A2，检测Acan-Gal-1对各指标的影响。通过Western blot、qRT-PCR等方法检测相关基因和蛋白的表达。通过生物信息学方法分析Acan-Gal-1蛋白结构特征，利用软件进行序列比对，预测其与Annexin ...
谢丽莎 +4 more
doaj
Recent Advances on Active Components and Functional Properties of Chinese Yam [PDF]
Yam as a medicinal and edible resource plant, is abundant in bioactive compounds including polysaccharides, polyphenols, allantoin, and saponins, these constituents endow yam with diverse functional properties, such as antioxidant, anti-diabetic, anti ...
Baodang GUO +6 more
core +1 more source