Results 21 to 30 of about 3,809 (118)

Injectable Biomimetic Composite Hydrogel Scaffold With Tissue‐Engineered Cartilage Matrix for Articular Cartilage Regeneration

Rare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu, Jun‐Jie Jiang, Hang Yao, Xian‐Feng Shang, Ming‐Di Zheng, Xu Hu, Shuo Xu, Jun‐Li Shi, Yan Han, Chi‐Run Wang, Qi Tao, Huai‐Guo Xue, Dong‐An Wang, Yu‐Chi Zhao   +13 more
wiley   +1 more source

Effect of a ceruminolytic ear cleaner on clinical, microbiological and ear canal microbiome evolution in canine erythemato‐ceruminous otitis externa associated with proliferation of Malassezia yeasts

Veterinary Dermatology, Volume 36, Issue 5, Page 668-678, October 2025.
Background – Erythemato‐ceruminous otitis externa (ECOE) is commonly associated with Malassezia spp. and microbial imbalance. Hypothesis/Objective – To assess the clinical performance of an ear cleaner in dogs suffering from ECOE associated with Malassezia spp. overgrowth and to measure its impact on the microbiota. Conclusions and Clinical Relevance –
Amaury Briand, Emmanuel Bensignor, Hélène Dropsy, Odile Crosaz, Louis Humeau, Justine Cheval, Vanessa Demontant, Melissa N. Debi, Oscar Fantini, Hélène Dal, Jacques Guillot, Noelle Cochet Faivre   +11 more
wiley   +1 more source

Implications of Tobacco Use on Pathogen‐Driven Diseases: A Public Health and Policy Perspective

World Medical &Health Policy, Volume 17, Issue 3, Page 468-474, September 2025.
ABSTRACT The tobacco epidemic remains one of the most significant global public health challenges, responsible for over 8 million deaths annually, with a substantial portion occurring among non‐smokers exposed to second‐hand smoke. While cigarette smoking remains the most prevalent form of tobacco use worldwide, the rise of electronic nicotine delivery
Nadine Kabbani, James L. Olds
wiley   +1 more source

Updated insights into the molecular pathogenesis of canine atopic dermatitis

Veterinary Dermatology, Volume 36, Issue 4, Page 375-384, August 2025.
Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley   +1 more source

Comparison of commercial next‐generation sequencing assays to conventional culture methods for bacterial identification and antimicrobial susceptibility of samples obtained from clinical cases of canine superficial bacterial folliculitis

Veterinary Dermatology, Volume 36, Issue 1, Page 14-23, February 2025.
Background – Bacterial identification and antimicrobial susceptibility testing is an important step in timely therapeutic decisions for canine superficial bacterial folliculitis (SBF), commonly caused by Staphylococcus pseudintermedius. Next‐generation sequencing (NGS) offers the appeal of potentially expedited results with complete detection of ...
Kimberly Smart, Jason B. Pieper, Austin K. Viall, James O. Noxon, Darren J. Berger   +4 more
wiley   +1 more source

PTEN and GATA3 as Key Molecular Mediators Linking Diabetes Mellitus to Osteoarthritis: A Comprehensive Mendelian Randomization, Bioinformatics, and Experimental Study

International Journal of Endocrinology, Volume 2025, Issue 1, 2025.
Background Epidemiological studies suggest a potential link between diabetes mellitus (DM) and osteoarthritis (OA), but the molecular mechanisms underlying this association remain unclear. Identifying these mechanisms is crucial for developing targeted therapies for diabetic patients with OA.
Jian Ding, Xuqiang Liu, Jun Zhang, Zhiping Zhang, Xiaofeng Li, Suraiya Saleem   +5 more
wiley   +1 more source

Gut microbiota dynamics of adult and sub‐adult sika deer during reintroduction 重引入过程中成年和亚成年梅花鹿肠道微生物的动态变化

Integrative Conservation, Volume 3, Issue 3, Page 257-270, September 2024.
Natural training enclosure design schematic. We selected 12 sika deer including six adults and six sub‐adults. Key considerations in the design of the natural training were to divide the training spatial ground into two parts (30 × 30 m small areas for isolation of new individuals and large areas measuring 200 × 600 m for free walking), and the ...
Wentao Zhang, Feifei Yang, Heng Bao, Jiale Sun, Wannian Cheng, Shiyu Chen, Nathan J. Roberts, Yanhui Guan, Shixian Guo, Jixu Sun, Guangshun Jiang   +10 more
wiley   +1 more source

Harnessing green microbiology for sustainable water management, agriculture, and energy generation: Current advances and future prospects

World Water Policy, Volume 10, Issue 3, Page 649-697, August 2024.
Abstract This article presents an in‐depth overview of recent developments and prospects in utilizing green microbiology for sustainable water management. It highlights its vital role across various aspects of water management while underscoring its significance for global development. This article delves deep into microbial processes integral to water
Adenike A. Akinsemolu, Helen Onyeaka, Foluke V. Arijeniwa   +2 more
wiley   +1 more source

microRNA-218通过靶向HOXA10抑制肝癌细胞的实验研究

Zhongguo shiyan zhenduanxue, 2019
微小RNA(microRNA,miRNAs)是一类长约22个核苷酸的单链非编码RNA,通过与靶mRNAs完全或不完全互补配对,导致靶基因降解或抑制其翻译,从而在基因的表达调控中发挥着重要作用。研究表明microRNAs参与了肝癌的发生、发展和侵袭转移的全过程[1,2]但是有关miR-218在肝癌(HCC)的生物学功能仍然未知 ...
肖钟迪, 王雅丽, 付凯
doaj  

环状RNA对心血管疾病的诊断价值

Zhongguo shiyan zhenduanxue, 2019
近年来随着非编码RNA的不段发现,越来越多的疾病和非编码RNA异常改变相关[1]。非编码RNA占据全部基因的99%以上[2],被认为在调控编码基因方面起到重要作用。随着微小RNA(miRNA),长链非编码RNA(lncRNA)研究的深入证实上述2种非编码RNA参与到包括肿瘤、神经、血液、心血管等疾病的发病和预后过程[3,4]。随后人们又发现更加稳定的非编码RNA-环状RNA,其广泛的存在于有机体内,因为不同于线性RNA,环状结构使其更加稳定的存在于体内 ...
张云飞, 陈晨, 赵惠敏, 刘杨
doaj