Results 21 to 30 of about 5,855 (151)
Study on the effect of myocardial injury induced by electrical injury in mice based on metabolomics [PDF]
Objective To study myocardial injury induced by electrical injury in mice based on metabolomics, and to find out the differential metabolites and pathways in cardiac metabolism omics.
CHEN Siyu +9 more
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, 2018 目的观察佐匹克隆与盐酸曲唑酮治疗睡眠障碍的临床疗效和安全性。方法将100例睡眠障碍患者采用随机数字表的方法分为治疗组50例和对照组50例。治疗组给予佐匹克隆治疗,对照组给予盐酸曲唑酮治疗。两组均为睡前30 min给药,疗程4周。比较两组临床治疗效果。结果治疗后,两种药品在延长患者总睡眠时间方面差异无统计学意义[(0.9±0.3)h比(0.9±0.7)h,P>0.05]。佐匹克隆治疗睡眠障碍的入睡时间评分低于盐酸曲唑酮[(0.5±0.2)分比(1.3±0.4)分,P0.05)。治疗组不良反应量表(TESS)
贺王伟, 黄宇, 黄峥嵘
core
, 2016 右佐匹克隆为快速短效非苯二氮 类镇静安眠药,该药为γ-氨基丁酸(GABA)受体激动剂,与苯二氮艹卓类结合于相同的受体和部位,作用区域不同,镇静、抗焦虑、肌肉松弛和抗惊厥的作用明显,且治疗失眠症的疗效与安全性均优于艾司唑仑~([1]),故在临床上较为常用。与此同时 ...
张云琛, 戴成家, 曾莉莉
core
Clinical and literature review of a case of myopathic form of carnitine palmitoyltransferase Ⅱ deficiency [PDF]
Objective To explore the correlations of genotype and phenotype of myopathic form of carnitine palmitoyltransferase Ⅱ (CPT Ⅱ) deficiency and to improve the clinical understanding of the disease.
LU Guangshuang, XIA Mingnong, CHENG Yun, HU Jie, LI Wenbo, ZHANG Fan, YANG Wu
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Giant Brunner’s gland adenoma of the duodenum complicated with bleeding: a case report [PDF]
, 2022 Brunner’s gland adenoma（BGA） of the duodenum is an extremely rare benign tumor in clinical practice. In this article， the diagnosis and treatment of one case of BGA of the duodenum were reported.
Xu Qi, Wang Yan, Tang Jing, Gao Fei, Zhang Jiewei, Zhuang Guifeng
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126例肠道病毒71型和柯萨奇A组共感的临床特征分析* [PDF]
Objective: To explore the attack, prevalence, clinical features, diagnosis, therapy and prognosis of enterovirus 71 and coxsackie A16. Methods: Analyzing the general situation, main symptoms and signs, laboratory examination, virus effect analysis and ...
Wang, Ji +4 more
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Marfan syndrome (MFS) is a dominant inherited connective tissue disease. It has variable clinical manifestations and affects a number of systems, such as the cardiovascular system, eyes, skeletal, lung, skin etc. Fibrillin-1（FBN1）gene mutations are found
Huang, Qi, Xu, Yao-feng
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Development and application of CK-MB specific monoclonal antibodies [PDF]
, 2017 本研究拟建立肌酸激酶同工酶MB(CK-MB)特异性单克隆抗体(mAb)的研制方法,对抗CK-MB单抗进行评价分类及性质鉴定,并初步建立CK-MB; 定量检测试剂。以CK-MB抗原免疫BALB/c小鼠,利用常规单抗制备技术,使用间接和捕获ELISA差异筛选法筛选单抗。利用肌酸激酶同工酶(CK-; MM/BB/MB)抗原对所制备单抗的抗原识别表位进行鉴定,另通过免疫印迹法及合成CK-MM、CK-BB差异性的线性表位肽鉴定对所制备的单抗进行评; 价分类。使用双抗体夹心ELISA方法筛选检测CK ...
周国梁 +7 more
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对数正态模型及饮酒房室模型在血药酒精浓度曲线模拟中的应用 [PDF]
, 2007 将对数正态模型和饮酒房室模型用于血药酒精浓度随时间变化曲线的模拟,对数正态模型和房室模型均能较好的模拟酒精血药浓度变化过程。配对t检验显示,对数正态模型与房室模型的模拟结果相一致;分别计算两种模拟结果的峰浓度和达峰时间 ...
温雅, 黎宁, 黎开书
core
The negative regulatory effect of connexin 43 on myocardial injury in rats with common bile duct ligation and its mechanism [PDF]
Objective To investigate the role and molecular mechanism of connexin 43 (Cx43) in rats with myocardial injury induced by common bile duct ligation (CBDL).
WANG Xiaoyu, LYU Lin, YANG Han, ZHU Lin, DONG Shengnan, DONG He
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