Results 1 to 10 of about 2,874 (102)

Study on Enzymatic Preparation and in vitro Stability of ACE Inhibitory Peptides from Cottonseed Protein(棉籽蛋白ACE抑制肽的酶法制备及其体外稳定性研究) [PDF]

Shipin kexue jishu xuebao, 2023
Angiotensin-I-converting enzyme (ACE) inhibitory peptides play an important role in the prevention and treatment of hypertension to improve human health, because of their characteristics of safety, no side effects, and easy absorption.
CHANG Chang(常畅), LIU Zhiping(刘治平), CHEN Zheyi(陈哲漪), YAN Qiaojuan(闫巧娟), JIANG Zhengqiang(江正强)   +4 more
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Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena 脑啡肽酶和脑啡肽酶抑制剂对葡萄糖稳态的影响:一个有争议的观点和有前景的领域

Journal of Diabetes, Volume 15, Issue 5, Page 397-408, May 2023., 2023
Highlights Neprilysin (NEP) inhibitors may lead to beneficial effects through inhibition of NEP, which involves impairment of glucose homeostasis through modulation of insulin resistance and the development of pancreatic β cell dysfunction as observed in type 2 diabetes mellitus.
Faisal Holil AlAnazi, Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb, Athanasios Alexiou, Marios Papadakis, Hanan A. Ogaly, Yousef Abud Alanazi, Hebatallah M. Saad, Gaber El‐Saber Batiha   +8 more
wiley   +1 more source

Dipeptidyl Peptidase-4 Inhibitory Activity of Casein Glycomacropeptide Hydrolysates(酪蛋白糖巨肽酶解物的二肽基肽酶-4抑制作用) [PDF]

Shipin kexue jishu xuebao, 2015
The aim of the present study was to investigate the dipeptidyl peptidase-4 (DPP-4) inhibitory activity of glycomacropeptide (GMP) hydrolysates obtained with papain, alkaline, trypsin and protease.
WANG Qian(王 倩), BAI Hanyu(白函瑜), MAO Xueying(毛学英)   +2 more
doaj   +1 more source

超声波辅助酶法制备辣木籽ACE抑制肽工艺优化Optimization of preparation of ACE inhibitory peptide from Moringa oleifera seeds by ultrasound-assisted enzymatic hydrolysis

Zhongguo youzhi, 2023
为进一步提高辣木籽蛋白资源的开发利用，采用盐提法提取辣木籽蛋白，再采用超声波辅助酶法制备辣木籽ACE抑制肽。以水解度和ACE抑制率为评价指标，通过单因素实验探究超声波功率、超声酶解时间、超声酶解温度及料液比对制备ACE抑制肽的影响,采用响应面法对制备工艺条件进行优化。结果表明：超声波辅助酶法制备辣木籽ACE抑制肽的最佳酶解工艺条件为碱性蛋白酶添加量5.5 mg/mL、pH 9、超声波功率500 W、超声酶解时间1.7 h、超声酶解温度55 ℃、料液比1∶ 45，在此条件下制备的酶解物ACE抑制率达到78.
钟玉旺，安姝璇，王雪峰，范江平，黄艾祥，田洋 ZHONG Yuwang, AN Shuxuan, WANG Xuefeng , FAN Jiangping, HUANG Aixiang, TIAN Yang
doaj   +1 more source

COVID‐19 and comorbidities: A role for dipeptidyl peptidase 4 (DPP4) in disease severity? 新冠肺炎与合并症:二肽基肽酶4在疾病严重程度中的作用?

Journal of Diabetes, Volume 12, Issue 9, Page 649-658, September 2020., 2020
Highlights Coronavirus disease 2019 (COVID‐19) is caused by SARS‐CoV‐2; recent modeling of the structure of SARS‐CoV‐2 spike glycoprotein, which mediates viral‐host‐cell entry, predicts interactions with dipeptidyl peptidase 4 (DPP4) in addition to angiotensin‐converting enzyme 2.
Margaret F. Bassendine, Simon H. Bridge, Geoffrey W. McCaughan, Mark D. Gorrell   +3 more
wiley   +1 more source

Purification and Characterization of Aminopeptidase B from Oysters (Alectryonella plicatula )(褶牡蛎氨肽酶B的分离纯化和性质研究) [PDF]

Shipin kexue jishu xuebao, 2017
Aminopeptidase is a kind of exopeptidases that specifically cleaves amino acids from the N-terminal of proteins, and thus has wild applications in food industry.
TANG Yi(唐逸), YAN Longjie(颜龙杰), ZHONG Chan(钟婵), ZHANG Lingjing(张凌晶), WENG Ling(翁凌), CAO Minji(曹敏杰)   +5 more
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Study on Isolation, Identification and Activity of Novel α-Glucosidase Inhibitory Peptide Derived from Dahe Black Pig Ham(大河乌猪火腿中新型α-葡萄糖苷酶抑制肽的分离、鉴定及活性研究) [PDF]

Shipin kexue jishu xuebao
Protein degradation during fermentation and maturation of Dahe black pig ham results in abundant bioactive peptides. In order to investigate whether there were α-glucosidase inhibitory peptides in Dahe black pig ham and its activity, ham peptides of ...
WANG Daodian(王道滇), WEI Guangqiang(魏光强), TAO Jifang(陶继芳), LI Xiang(李祥), ZHAO Xingwen(赵兴文), HUANG Aixiang(黄艾祥)   +5 more
doaj   +1 more source

Enzymatic Preparation and Inhibitory Mechanism of Xanthine Oxidase Inhibitory Peptides from Undaria pinnatifida Proteins(裙带菜蛋白黄嘌呤氧化酶抑制肽的酶法制备及作用机制) [PDF]

Shipin kexue jishu xuebao
Foodborne xanthine oxidase (XO) inhibitory peptides can decrease the production of uric acid via inhibiting the activity of XO, in order to relieve hyperuricemia.
CHANG Chang(常畅), CHEN Zheyi(陈哲漪), ZHANG Hong(张泓), YAN Qiaojuan(闫巧娟), JIANG Zhengqiang(江正强)   +4 more
doaj   +1 more source

原料压榨制油的预处理方式对核桃多肽功能特性 和ACE抑制活性的影响Effect of raw material pretreatment method in oil pressing on functional characteristics and ACE inhibitory activity of walnut polypeptide

Zhongguo youzhi, 2023
旨在研究原料压榨制油的预处理方式对核桃多肽性质的影响。对核桃仁分别进行未预处理、去衣、焙烤预处理后，进行压榨提油，以提油后的饼为原料，经正己烷脱脂，碱性蛋白酶酶解制备核桃多肽，测定核桃多肽的功能特性和ACE抑制活性。结果表明：与未预处理、焙烤预处理比较，去衣预处理的核桃多肽的持水性(50 ℃，5.11 g/g)、吸油性(50 ℃，3.25 g/g)、乳化性(pH 9.0,6257%)、乳化稳定性(pH 9.0,84.51%)、起泡性(pH 9.0,117.49%)及ACE抑制率（63.04%）最高 ...
高盼1,2，韩玉博1，杨永2，马开创1，钟武1,2，胡传荣1， 何东平1,2，张晖3，张跃进4，王兴国1,3 GAO Pan1,2, HAN Yubo1, YANG Yong2, MA Kaichuang1, ZHONG Wu1,2, HU Chuanrong1, HE Dongping1,2, ZHANG Hui3, ZHANG Yuejin4, WANG Xingguo1,3
doaj   +1 more source

红仁核桃多肽的制备工艺优化及降血脂功能研究Optimization of the preparation process of red kernel walnut polypeptide and its hypolipidemic effect

Zhongguo youzhi, 2023
为对红仁核桃的精深加工及其保健功能提供参考，以红仁核桃分离蛋白为原料对其进行酶解制备红仁核桃多肽，采用单因素试验和正交试验优化酶解工艺条件，并经超滤分离得到3个组分的红仁核桃多肽，测定其多肽含量、胰脂肪酶抑制率和胆固醇胶束溶解度抑制率。以高血脂SD大鼠为模型，分别以活性最高的红仁核桃多肽的低、中、高剂量（200、400、800 mg/kg）饲喂大鼠28 d，测定大鼠体质量、脏器质量和血清指标，并进行组织切片观察。结果表明：红仁核桃多肽制备的最佳条件为酶解pH 9.0、底物质量分数4.0%、酶加入量 ...
吴淑娟1，王锐2，董兆斌3，夏禹承1，廖玉美4，张润光1，张有林1 WU Shujuan1, WANG Rui2, DONG Zhaobin3, XIA Yucheng1, LIAO Yumei4, ZHANG Runguang1, ZHANG Youlin1
doaj   +1 more source