Results 11 to 20 of about 510 (131)

肾移植术后重症肺炎的诊治

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2008
【目的】 探讨肾移植术后重症肺炎的诊断和治疗经验? 【方法】 对24例肾移植术后重症肺炎患者的临床资料进行回顾性分析.所有患者通过痰?中段尿?咽拭子或支气管肺泡灌洗液(BAL)及血标本的检查进行病原学诊断,并给予减少或者撤除免疫抑制剂?经验性使用抗感染药物?甲基强的松龙?丙种球蛋白?无创通气或者气管插管及全身支持治疗等综合治疗?
doaj   +1 more source

The Study of the Value of High Mobility Group Protein B1 Combined with Acute Physiological Score in the Diagnosis and Prognosis of Children with Severe Pneumonia [PDF]

open access: yes, 2022
BackgroundSevere pneumonia in children is a common respiratory critical illness, and accurate assessment of its prognosis is the key to reasonable clinical decision-making. High mobility group protein B1 (HMGB1) and acute physiology score (APS) have high
KANG Ping, LI Yi, TANG Yu
core   +1 more source

Effect of montelukast on leukotriene B4 metabolism in asthma [PDF]

open access: yes, 2023
Objective·To observe the effect of montelukast on the expressions of key genes in LTB4 (leukotriene B4) metabolic pathway in treating asthma and investigate the candidate intervene targets of asthma.Methods·The acute, subacute, and chronic asthmatic ...
FU Hongling   +6 more
core   +1 more source

Fulminant psittacosis complicated with multiple organ dysfunction syndrome: a case report [PDF]

open access: yes, 2023
The cases of fulminant psittacosis complicated with multiple organ dysfunction syndrome (MODS) have been rarely reported in China. In this article, clinical manifestations and treatment of a patient with fulminant psittacosis complicated with MODS were ...
Qian Xueqin, Wang Yi, Zhang Huitao, Shen Dezhi, Huang Kaizhuang, Zhu Yaoli
core   +1 more source

Latest Research Development in Histone Acetylation in the Pathogenesis of Asthma [PDF]

open access: yes, 2022
Asthma is primarily marked by airway hyperresponsiveness, inflammation, and remodeling. Histone acetylation is one of the most common epigenetic modifications that regulates histone acetyltransferase and histone deacetylase, and imbalanced regulation may
CHEN Shaopeng, ZENG Minjuan, LAI Tianwen
core   +1 more source

Novel Developments in the Relationship of Gut Microbiota and Immune Regulation with Childhood Asthma [PDF]

open access: yes, 2022
Bronchial asthma, commonly known as asthma, is a frequently seen chronic respiratory disease that seriously threatens human health. More than 300 million people have had asthma worldwide, and most of them are children. Epidemiological investigations have
CUI Tianyi, LIU Jiarui, LYU Bin, GAO Xiumei, ZHAO Xin
core   +1 more source

New insights in small airway dysfunction of childhood asthma [PDF]

open access: yes, 2023
Small airway dysfunction (SAD) widely exists in different stages of childhood asthma, which is based on airway inflammation, airway remodeling and airway hyperresponsiveness. Among them, airway inflammation is the main pathological feature of SAD. It has
DONG Xiaoyan, ZHU Siyu
core   +1 more source

Effect of Integrated Chinese and Western Medicine Treatment on Immune Factors in a Rat Model with Phlegm-heat Syndrome in Acute Exacerbation-stable Stage of Chronic Obstructive Pulmonary Disease [PDF]

open access: yes, 2022
BackgroundSecretory immunoglobulin A (sIgA) deficiency and immune imbalance caused by T lymphocyte aggregation in lung tissue are associated with the development of chronic obstructive pulmonary disease (COPD) .
LI Xiaojun, LI Ya, BIAN Qingqing, XUAN Yinshuang, SHEN Tingting, LI Suyun
core   +1 more source

Macrophage differential genes and their functions in silicosis based on single cell RNA sequencing and spatial transcriptome sequencing [PDF]

open access: yes, 2022
BackgroundThe rise of single cell RNA sequencing (scRNA-seq) and spatial transcriptome sequencing technologies has allowed for intensive study of lung diseases, but both have been poorly studied in silicosis.
Jie CHAO, Wei ZHANG, Xinbei ZHOU
core   +2 more sources

Significance of changes in levels of neutrophil extracellular traps during development of silicosis in mice [PDF]

open access: yes
BackgroundSilicosis is an occupational disease mainly characterized by pulmonary progressive fibrosis induced by the accumulation of free silica (SiO2) in the lungs due to long-term exposure to SiO2 dust.
Hailan HE   +7 more
core   +1 more source

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