Interference of Homologous Sequences on the SNP Study of CYP2A13 Gene [PDF]
, 2010 Background and objective It has been proven that cytochrome P450 enzyme 2A13 (CYP2A13) played an important role in the association between single nucleotide polymorphisms (SNP) and human diseases.
Chaorong MEI +7 more
core
Investigation of the association between adult intelligence and Apolipoprotein E genotype in the young Chinese Han population [PDF]
, 2015 载脂蛋白E（ApolipoproteinE）在脂质代谢及分布中具有重要作用。载脂蛋白E基因具有多态性，包含了APOEɛ2、APOEɛ3和APOEɛ4三种。其中，ɛ4等位基因是引起迟发型阿尔茨海默病（Late-onsetAlzheimer’sDisease）最重要的危险因素。尽管许多研究表明在老年人中APOE基因的多态性与认知功能密切相关，但其对青年人认知功能的影响研究非常少，并且有限的研究结果存在争议性。为了进一步探讨APOE基因多态性对青年人认知功能的影响 ...
魏孜辰
core
Genetic Polymorphism and Forensic Application of 47 Autosomal InDel Loci in 5 Chinese Ethnic Groups [PDF]
, 2020 Objective To investigate the population genetic data of 47 autosomal insertion/deletion （InDel） polymorphism genetic markers involved in AGCU InDel 50 kit in Guangdong Han, Guangxi Zhuang, Guangxi Yao, Guangxi Jing, and Guangxi Mulam, and to evaluate ...
PAN Xi-yong, LIU Chang-hui, DU Wei-an, et al
core +1 more source
Research Progress on Individual Identification by Frontal Sinus Imaging [PDF]
, 2021 Frontal sinus imaging is an important research object in forensic individual identification due to the highly specific irregular air cavity shape of frontal sinus, the stability of its shape after maturity, and the wide clinical application of radiology ...
WU Wei, LI Yuan, FAN Fei, et al.
core +1 more source
The screening and function study of risk factors and biomarkers for Leukoaraiosis in Chinese-Han population [PDF]
, 2016 脑白质疏松症(Leukoaraiosis，LA)，也被称作为脑白质损伤(whitematterlesions，WMLs)和脑白质高信号(whitematterhyperintensities，WMHs)，是一种广泛存在于老年人群中的神经影像现象。LA虽不表现出具体的临床症状，但也非良性无危害的。它会增加认知功能下降、步态异常和跌倒、抑郁、中风、痴呆和尿失禁，甚至死亡的发生风险。随着人口老龄化速度的加快，LA正成为全球重大的老年医学问题。在西方国家，科学家们发现LA具有较大的遗传力，其中存在大量的易感基因，
黄文清
core
Evaluation of Detection Efficiency for Trio Full Sibling Testing [PDF]
, 2023 Objective To study the detection efficiency of trio full sibling with another known full sibling reference added under different number of autosomal STR typing systems. Methods Based on 43 detection systems consisting of 13 to 55 representative autosomal
Hui CHEN, Ran LI, Yu ZANG, Jing-yi YANG, Ri-ga WU, Hong-yu SUN
core +1 more source
中国吉林省地区朝鲜族及汉族正常人群内皮型一氧化氮合酶基因4a/bVNTR多态性分布的比较研究
Zhongguo shiyan zhenduanxue, 2013 目的分析我国吉林省地区朝鲜族及汉族健康人群内皮型一氧化氮合酶（endothelial nitric oxide synthase,eNOS）基因4a/bVNTR多态性的分布。方法应用聚合酶链式反应（polymerase chain reaction,PCR）技术,检测183例吉林省正常人（其中朝鲜族人群92例,汉族人群91例）eNOS基因多态性,并结合统计学软件分析其分布特点。结果我国吉林省朝鲜族人群eNOS基因4a/bVNTR的aa、ab和bb基因频率分别为0.043 48、0.304 3和0.652
李淼 +5 more
doaj
吉林省地区朝鲜族和汉族健康人群LPL基因HindⅢ酶切位点多态性分布的研究
Zhongguo shiyan zhenduanxue, 2010 目的分析我国吉林省地区朝鲜族和汉族健康人群脂蛋白酯酶（lipoprotein lipase,LPL）基因HindⅢ酶切位点多态性的分布。方法应用聚合酶链反应（polimerase chain reaction,PCR）等技术检测66例朝鲜族和90例汉族LPL基因多态性,并将其基因型和等位基因在两族人群中的分布进行统计学分析。结果朝鲜族人群LPL基因P+P+基因型,P+P-基因型和P-P-基因型频率分别为57.58%,33.33%和9.09%;汉族人群分别为73.33%,24.44%和2.22 ...
安仙泉 +5 more
doaj
Correlation of ATP Binding Cassette Transporter A1 Gene Polymorphisms and Lower Extremity Atherosclerotic Disease [PDF]
, 2017 目的：进行三磷酸腺苷结合盒转运体A1（ATP binding cassette transporter A1,ABCA1）基因单核苷酸多态性（single nucleotide polymorphisms,SNP）与下肢动脉粥样硬化（lower extremity atherosclerotic disease,LEAD）的关联分析。方法：收集福建省闽南地区630例体检者（314例LEAD者和316例正常者）的临床资料及外周血;采用Sequenom Mass ...
戴成家, 林小凤, 费燕, 连霞
core
From the “Out of Africa Theory” Study to the Application of “DNA Biogeographic Ancestry Inference” in Criminal Investigation [PDF]
, 2019 Genetic markers, such as single nucleotide polymorphism （SNP）, insertion/deletion （InDel）, were discovered and widely used with the development of whole genome sequencing and bioinformatics technology.
JIANG Li, LIU Jing, LI Cai-xia
core +1 more source